Identification
HMDB Protein ID CDBP04741
Secondary Accession Numbers Not Available
Name Fibroblast growth factor 6
Description Not Available
Synonyms
  1. FGF-6
  2. HBGF-6
  3. HST-2
  4. HSTF-2
  5. Heparin secretory-transforming protein 2
  6. Heparin-binding growth factor 6
Gene Name FGF6
Protein Type Receptor
Biological Properties
General Function Involved in growth factor activity
Specific Function Can transform NIH 3T3 cells. Exhibits strong mitogenic and angiogenic properties
GO Classification
Function
binding
protein binding
receptor binding
growth factor activity
Cellular Location
  1. Secreted
  2. extracellular space
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12p13
SNPs FGF6
Gene Sequence
>627 bp
ATGGCCCTGGGACAGAAACTGTTCATCACTATGTCCCGGGGAGCAGGACGTCTGCAGGGC
ACGCTGTGGGCTCTCGTCTTCCTAGGCATCCTAGTGGGCATGGTGGTGCCCTCGCCTGCA
GGCACCCGTGCCAACAACACGCTGCTGGACTCGAGGGGCTGGGGCACCCTGCTGTCCAGG
TCTCGCGCGGGGCTAGCTGGAGAGATTGCCGGGGTGAACTGGGAAAGTGGCTATTTGGTG
GGGATCAAGCGGCAGCGGAGGCTCTACTGCAACGTGGGCATCGGCTTTCACCTCCAGGTG
CTCCCCGACGGCCGGATCAGCGGGACCCACGAGGAGAACCCCTACAGCCTGCTGGAAATT
TCCACTGTGGAGCGAGGCGTGGTGAGTCTCTTTGGAGTGAGAAGTGCCCTCTTCGTTGCC
ATGAACAGTAAAGGAAGATTGTACGCAACGCCCAGCTTCCAAGAAGAATGCAAGTTCAGA
GAAACCCTCCTGCCCAACAATTACAATGCCTACGAGTCAGACTTGTACCAAGGGACCTAC
ATTGCCCTGAGCAAATACGGACGGGTAAAGCGGGGCAGCAAGGTGTCCCCGATCATGACT
GTCACTCATTTCCTTCCCAGGATCTAA
Protein Properties
Number of Residues 208
Molecular Weight 22904.3
Theoretical pI 10.39
Pfam Domain Function
Signals
  • ["1-37"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Fibroblast growth factor 6
MALGQKLFITMSRGAGRLQGTLWALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSR
SRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEI
STVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTY
IALSKYGRVKRGSKVSPIMTVTHFLPRI
GenBank ID Protein 45934424
UniProtKB/Swiss-Prot ID P10767
UniProtKB/Swiss-Prot Entry Name FGF6_HUMAN
PDB IDs Not Available
GenBank Gene ID AY581424
GeneCard ID FGF6
GenAtlas ID FGF6
HGNC ID HGNC:3684
References
General References Not Available