Identification |
HMDB Protein ID
| CDBP04741 |
Secondary Accession Numbers
| Not Available |
Name
| Fibroblast growth factor 6 |
Description
| Not Available |
Synonyms
|
- FGF-6
- HBGF-6
- HST-2
- HSTF-2
- Heparin secretory-transforming protein 2
- Heparin-binding growth factor 6
|
Gene Name
| FGF6 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in growth factor activity |
Specific Function
| Can transform NIH 3T3 cells. Exhibits strong mitogenic and angiogenic properties |
GO Classification
|
Function |
binding |
protein binding |
receptor binding |
growth factor activity |
|
Cellular Location
|
- Secreted
- extracellular space
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 12p13 |
SNPs
| FGF6 |
Gene Sequence
|
>627 bp
ATGGCCCTGGGACAGAAACTGTTCATCACTATGTCCCGGGGAGCAGGACGTCTGCAGGGC
ACGCTGTGGGCTCTCGTCTTCCTAGGCATCCTAGTGGGCATGGTGGTGCCCTCGCCTGCA
GGCACCCGTGCCAACAACACGCTGCTGGACTCGAGGGGCTGGGGCACCCTGCTGTCCAGG
TCTCGCGCGGGGCTAGCTGGAGAGATTGCCGGGGTGAACTGGGAAAGTGGCTATTTGGTG
GGGATCAAGCGGCAGCGGAGGCTCTACTGCAACGTGGGCATCGGCTTTCACCTCCAGGTG
CTCCCCGACGGCCGGATCAGCGGGACCCACGAGGAGAACCCCTACAGCCTGCTGGAAATT
TCCACTGTGGAGCGAGGCGTGGTGAGTCTCTTTGGAGTGAGAAGTGCCCTCTTCGTTGCC
ATGAACAGTAAAGGAAGATTGTACGCAACGCCCAGCTTCCAAGAAGAATGCAAGTTCAGA
GAAACCCTCCTGCCCAACAATTACAATGCCTACGAGTCAGACTTGTACCAAGGGACCTAC
ATTGCCCTGAGCAAATACGGACGGGTAAAGCGGGGCAGCAAGGTGTCCCCGATCATGACT
GTCACTCATTTCCTTCCCAGGATCTAA
|
Protein Properties |
Number of Residues
| 208 |
Molecular Weight
| 22904.3 |
Theoretical pI
| 10.39 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Fibroblast growth factor 6
MALGQKLFITMSRGAGRLQGTLWALVFLGILVGMVVPSPAGTRANNTLLDSRGWGTLLSR
SRAGLAGEIAGVNWESGYLVGIKRQRRLYCNVGIGFHLQVLPDGRISGTHEENPYSLLEI
STVERGVVSLFGVRSALFVAMNSKGRLYATPSFQEECKFRETLLPNNYNAYESDLYQGTY
IALSKYGRVKRGSKVSPIMTVTHFLPRI
|
External Links |
GenBank ID Protein
| 45934424 |
UniProtKB/Swiss-Prot ID
| P10767 |
UniProtKB/Swiss-Prot Entry Name
| FGF6_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AY581424 |
GeneCard ID
| FGF6 |
GenAtlas ID
| FGF6 |
HGNC ID
| HGNC:3684 |
References |
General References
| Not Available |