Identification |
HMDB Protein ID
| CDBP04737 |
Secondary Accession Numbers
| Not Available |
Name
| Fibroblast growth factor 4 |
Description
| Not Available |
Synonyms
|
- FGF-4
- HBGF-4
- HST
- HST-1
- HSTF-1
- Heparin secretory-transforming protein 1
- Heparin-binding growth factor 4
- Transforming protein KS3
|
Gene Name
| FGF4 |
Protein Type
| Receptor |
Biological Properties |
General Function
| Involved in growth factor activity |
Specific Function
| Can transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity |
GO Classification
|
Function |
binding |
protein binding |
receptor binding |
growth factor activity |
|
Cellular Location
|
- Secreted (Potential)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 11q13.3 |
SNPs
| FGF4 |
Gene Sequence
|
>621 bp
ATGTCGGGGCCCGGGACGGCCGCGGTAGCGCTGCTCCCGGCGGTCCTGCTGGCCTTGCTG
GCGCCCTGGGCGGGCCGAGGGGGCGCCGCCGCACCCACTGCACCCAACGGCACGCTGGAG
GCCGAGCTGGAGCGCCGCTGGGAGAGCCTGGTGGCGCTCTCGTTGGCGCGCCTGCCGGTG
GCAGCGCAGCCCAAGGAGGCGGCCGTCCAGAGCGGCGCCGGCGACTACCTGCTGGGCATC
AAGCGGCTGCGGCGGCTCTACTGCAACGTGGGCATCGGCTTCCACCTCCAGGCGCTCCCC
GACGGCCGCATCGGCGGCGCGCACGCGGACACCCGCGACAGCCTGCTGGAGCTCTCGCCC
GTGGAGCGGGGCGTGGTGAGCATCTTCGGCGTGGCCAGCCGGTTCTTCGTGGCCATGAGC
AGCAAGGGCAAGCTCTATGGCTCGCCCTTCTTCACCGATGAGTGCACGTTCAAGGAGATT
CTCCTTCCCAACAACTACAACGCCTACGAGTCCTACAAGTACCCCGGCATGTTCATCGCC
CTGAGCAAGAATGGGAAGACCAAGAAGGGGAACCGAGTGTCGCCCACCATGAAGGTCACC
CACTTCCTCCCCAGGCTGTGA
|
Protein Properties |
Number of Residues
| 206 |
Molecular Weight
| 22047.4 |
Theoretical pI
| 10.19 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Fibroblast growth factor 4
MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV
AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP
VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA
LSKNGKTKKGNRVSPTMKVTHFLPRL
|
External Links |
GenBank ID Protein
| 386788 |
UniProtKB/Swiss-Prot ID
| P08620 |
UniProtKB/Swiss-Prot Entry Name
| FGF4_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| J02986 |
GeneCard ID
| FGF4 |
GenAtlas ID
| FGF4 |
HGNC ID
| HGNC:3682 |
References |
General References
| Not Available |