Identification
HMDB Protein ID CDBP04737
Secondary Accession Numbers Not Available
Name Fibroblast growth factor 4
Description Not Available
Synonyms
  1. FGF-4
  2. HBGF-4
  3. HST
  4. HST-1
  5. HSTF-1
  6. Heparin secretory-transforming protein 1
  7. Heparin-binding growth factor 4
  8. Transforming protein KS3
Gene Name FGF4
Protein Type Receptor
Biological Properties
General Function Involved in growth factor activity
Specific Function Can transform NIH 3T3 cells from a human stomach tumor (hst) and from karposi's sarcoma (KS3). It has a mitogenic activity
GO Classification
Function
binding
protein binding
receptor binding
growth factor activity
Cellular Location
  1. Secreted (Potential)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 11q13.3
SNPs FGF4
Gene Sequence
>621 bp
ATGTCGGGGCCCGGGACGGCCGCGGTAGCGCTGCTCCCGGCGGTCCTGCTGGCCTTGCTG
GCGCCCTGGGCGGGCCGAGGGGGCGCCGCCGCACCCACTGCACCCAACGGCACGCTGGAG
GCCGAGCTGGAGCGCCGCTGGGAGAGCCTGGTGGCGCTCTCGTTGGCGCGCCTGCCGGTG
GCAGCGCAGCCCAAGGAGGCGGCCGTCCAGAGCGGCGCCGGCGACTACCTGCTGGGCATC
AAGCGGCTGCGGCGGCTCTACTGCAACGTGGGCATCGGCTTCCACCTCCAGGCGCTCCCC
GACGGCCGCATCGGCGGCGCGCACGCGGACACCCGCGACAGCCTGCTGGAGCTCTCGCCC
GTGGAGCGGGGCGTGGTGAGCATCTTCGGCGTGGCCAGCCGGTTCTTCGTGGCCATGAGC
AGCAAGGGCAAGCTCTATGGCTCGCCCTTCTTCACCGATGAGTGCACGTTCAAGGAGATT
CTCCTTCCCAACAACTACAACGCCTACGAGTCCTACAAGTACCCCGGCATGTTCATCGCC
CTGAGCAAGAATGGGAAGACCAAGAAGGGGAACCGAGTGTCGCCCACCATGAAGGTCACC
CACTTCCTCCCCAGGCTGTGA
Protein Properties
Number of Residues 206
Molecular Weight 22047.4
Theoretical pI 10.19
Pfam Domain Function
Signals
  • ["1-30"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Fibroblast growth factor 4
MSGPGTAAVALLPAVLLALLAPWAGRGGAAAPTAPNGTLEAELERRWESLVALSLARLPV
AAQPKEAAVQSGAGDYLLGIKRLRRLYCNVGIGFHLQALPDGRIGGAHADTRDSLLELSP
VERGVVSIFGVASRFFVAMSSKGKLYGSPFFTDECTFKEILLPNNYNAYESYKYPGMFIA
LSKNGKTKKGNRVSPTMKVTHFLPRL
GenBank ID Protein 386788
UniProtKB/Swiss-Prot ID P08620
UniProtKB/Swiss-Prot Entry Name FGF4_HUMAN
PDB IDs
GenBank Gene ID J02986
GeneCard ID FGF4
GenAtlas ID FGF4
HGNC ID HGNC:3682
References
General References Not Available