Identification
HMDB Protein ID CDBP04711
Secondary Accession Numbers Not Available
Name Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
Description Not Available
Synonyms
  1. hLHPP
Gene Name LHPP
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency (By similarity).
GO Classification
Biological Process
protein dephosphorylation
Cellular Component
cytosol
nucleus
Function
catalytic activity
hydrolase activity
Molecular Function
magnesium ion binding
phosphohistidine phosphatase activity
inorganic diphosphatase activity
Process
metabolic process
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location 10
Locus 10q26.13
SNPs LHPP
Gene Sequence
>813 bp
ATGGCACCGTGGGGCAAGCGGCTGGCTGGCGTGCGCGGGGTGCTGCTTGACATCTCGGGC
GTGCTGTACGACAGCGGCGCGGGCGGCGGCACGGCCATCGCCGGCTCGGTGGAGGCGGTG
GCCAGACTGAAGCGTTCCCGGCTGAAGGTGAGGTTCTGCACCAACGAGTCGCAGAAGTCC
CGGGCAGAGCTGGTGGGGCAGCTTCAGAGGCTGGGATTTGACATCTCTGAGCAGGAGGTG
ACCGCCCCGGCACCAGCTGCCTGCCAGATCCTGAAGGAGCGAGGCCTGCGACCATACCTG
CTCATCCATGACGGAGTCCGCTCAGAATTTGATCAGATCGACACATCCAACCCAAACTGT
GTGGTAATTGCAGACGCAGGAGAAAGCTTTTCTTATCAAAACATGAATAACGCCTTCCAG
GTGCTCATGGAGCTGGAAAAACCTGTGCTCATATCACTGGGAAAAGGGCGTTACTACAAG
GAGACCTCTGGCCTGATGCTGGACGTTGGTCCCTACATGAAGGCGCTTGAGTATGCCTGT
GGCATCAAAGCCGAGGTGGTGGGGAAGCCTTCTCCTGAGTTTTTCAAGTCTGCCCTGCAA
GCGATAGGAGTGGAAGCCCACCAGGCCGTCATGATTGGGGACGATATCGTGGGCGACGTC
GGCGGTGCCCAGCGGTGTGGAATGAGAGCGCTGCAGGTGCGCACCGGGAAGTTCAGGCCC
AGTGACGAGCACCATCCGGAAGTGAAGGCTGATGGGTACGTGGACAACCTCGCAGAGGCA
GTGGACCTGCTGCTGCAGCACGCCGACAAGTGA
Protein Properties
Number of Residues 270
Molecular Weight 22695.865
Theoretical pI 7.208
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Phospholysine phosphohistidine inorganic pyrophosphate phosphatase
MAPWGKRLAGVRGVLLDISGVLYDSGAGGGTAIAGSVEAVARLKRSRLKVRFCTNESQKS
RAELVGQLQRLGFDISEQEVTAPAPAACQILKEQGLRPYLLIHDGVRSEFDQIDTSNPNC
VVIADAGESFSYQNMNNAFQVLMELEKPVLISLGKGRYYKETSGLMLDVGPYMKALEYAC
GIKAEVVGKPSPEFFKSALQAIGVEAHQAVMIGDDIVGDVGGAQRCGMRALQVRTGKFRP
SDEHHPEVKADGYVDNLAEAVDLLLQHADK
GenBank ID Protein 10716807
UniProtKB/Swiss-Prot ID Q9H008
UniProtKB/Swiss-Prot Entry Name LHPP_HUMAN
PDB IDs
GenBank Gene ID AB049629
GeneCard ID LHPP
GenAtlas ID LHPP
HGNC ID HGNC:30042
References
General References Not Available