Showing Protein GDP-fucose protein O-fucosyltransferase 2 (CDBP04702)
| Identification | |
|---|---|
| HMDB Protein ID | CDBP04702 |
| Secondary Accession Numbers | Not Available |
| Name | GDP-fucose protein O-fucosyltransferase 2 |
| Description | Not Available |
| Synonyms |
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| Gene Name | POFUT2 |
| Protein Type | Enzyme |
| Biological Properties | |
| General Function | Involved in peptide-O-fucosyltransferase activity |
| Specific Function | Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in thrombospondin type 1 repeats |
| GO Classification | Not Available |
| Cellular Location |
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| Pathways | Not Available |
| Gene Properties | |
| Chromosome Location | Chromosome:2 |
| Locus | 21q22.3 |
| SNPs | POFUT2 |
| Gene Sequence |
>1290 bp ATGGCGACACTCAGCTTCGTCTTCCTGCTGCTGGGGGCAGTGTCCTGGCCTCCGGCTTCT GCCTCCGGCCAGGAGTTCTGGCCCGGACAATCGGCGGCCGATATTCTGTCGGGGGCGGCT TCCCGCAGACGGTATCTTCTGTATGACGTCAACCCCCCGGAAGGCTTCAACCTGCGCAGG GATGTCTATATCCGAATCGCCTCTCTCCTGAAGACTCTGCTGAAGACGGAGGAGTGGGTG CTTGTCCTGCCTCCATGGGGCCGCCTCTATCACTGGCAGAGTCCTGACATCCACCAGGTC CGGATTCCCTGGTCTGAGTTTTTTGATCTTCCAAGTCTCAATAAAAACATCCCCGTCATC GAGTATGAGCAGTTCATCGCAGAATCTGGTGGGCCCTTTATTGACCAGGTTTACGTCCTG CAAAGTTACGCAGAGGGGTGGAAAGAAGGGACCTGGGAAGAGAAGGTGGACGAGCGGCCG TGTATTGATCAGCTCCTGTACTCCCAGGACAAGCACGAGTACTACAGAGGATGGTTTTGG GGTTATGAGGAGACCAGGGGTCTAAACGTCTCCTGTCTGTCCGTCCAGGGCTCAGCCTCC ATCGTGGCGCCCCTGCTGCTGAGAAACACATCAGCCCGGTCCGTGATGTTAGACAGAGCC GAGAACCTACTTCACGACCACTATGGAGGGAAAGAATACTGGGATACCCGTCGCAGCATG GTGTTTGCCAGGCACCTGCGGGAGGTGGGAGACGAGTTCAGGAGCAGACATCTCAACTCC ACGGACGACGCAGACAGGATCCCCTTCCAGGAGGACTGGATGAAGATGAAGGTCAAGCTG GGCTCCGCGCTAGGGGGCCCCTACCTGGGAGTCCACCTGAGAAGAAAAGATTTCATCTGG GGTCACAGACAGGATGTACCCAGTCTGGAAGGGGCCGTGAGGAAGATCCGCAGCCTCATG AAGACCCACCGGCTGGACAAGGTGTTTGTGGCCACAGATGCCGTCAGAAAGGAATATGAA GAGCTAAAAAAGCTGTTACCCGAGATGGTGAGGTTTGAACCCACGTGGGAGGAGCTGGAG CTCTACAAGGACGGAGGCGTTGCGATTATTGACCAGTGGATCTGCGCACACGCCAGGTTT TTTATTGGCACCTCAGTCTCAACATTTTCTTTTCGGATTCATGAGGAAAGAGAAATCCTG GGGTTGGACCCCAAGACGACGTACAACAGGTTCTGCGGAGACCAAGAGAAGGCGTGTGAG CAACCCACCCACTGGAAGATCACCTACTGA |
| Protein Properties | |
| Number of Residues | 429 |
| Molecular Weight | 49975.4 |
| Theoretical pI | 6.58 |
| Pfam Domain Function |
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| Signals |
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| Transmembrane Regions |
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| Protein Sequence |
>GDP-fucose protein O-fucosyltransferase 2 MATLSFVFLLLGAVSWPPASASGQEFWPGQSAADILSGAASRRRYLLYDVNPPEGFNLRR DVYIRIASLLKTLLKTEEWVLVLPPWGRLYHWQSPDIHQVRIPWSEFFDLPSLNKNIPVI EYEQFIAESGGPFIDQVYVLQSYAEGWKEGTWEEKVDERPCIDQLLYSQDKHEYYRGWFW GYEETRGLNVSCLSVQGSASIVAPLLLRNTSARSVMLDRAENLLHDHYGGKEYWDTRRSM VFARHLREVGDEFRSRHLNSTDDADRIPFQEDWMKMKVKLGSALGGPYLGVHLRRKDFIW GHRQDVPSLEGAVRKIRSLMKTHRLDKVFVATDAVRKEYEELKKLLPEMVRFEPTWEELE LYKDGGVAIIDQWICAHARFFIGTSVSTFSFRIHEEREILGLDPKTTYNRFCGDQEKACE QPTHWKITY |
| External Links | |
| GenBank ID Protein | 34147487 |
| UniProtKB/Swiss-Prot ID | Q9Y2G5 |
| UniProtKB/Swiss-Prot Entry Name | OFUT2_HUMAN |
| PDB IDs | Not Available |
| GenBank Gene ID | NM_133635.4 |
| GeneCard ID | POFUT2 |
| GenAtlas ID | POFUT2 |
| HGNC ID | HGNC:14683 |
| References | |
| General References | Not Available |