Cannabis Compound Database: Showing Protein Ubiquitin carboxyl-terminal hydrolase 17 (CDBP04685)

Identification Biological properties Gene properties Protein properties External links References XML Show 0 compounds

Identification

HMDB Protein ID

CDBP04685

Secondary Accession Numbers

Not Available

Name

Ubiquitin carboxyl-terminal hydrolase 17

Description

Not Available

Synonyms

Deubiquitinating enzyme 17
Ubiquitin thiolesterase 17
Ubiquitin-specific-processing protease 17

Gene Name

USP17A

Protein Type

Enzyme

Biological Properties

General Function

Involved in ubiquitin thiolesterase activity

Specific Function

Functions in cell apoptosis. Cleaves ubiquitin fusion protein substrates. May also bind hyaluronan and RNA

GO Classification

Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
ubiquitin thiolesterase activity
thiolester hydrolase activity
Process
ubiquitin-dependent protein catabolic process
metabolic process
catabolic process
macromolecule catabolic process
cellular macromolecule catabolic process
modification-dependent macromolecule catabolic process
modification-dependent protein catabolic process

Cellular Location

Nucleus
nucleolus

Pathways

Not Available

Gene Properties

Chromosome Location

Not Available

Locus

Not Available

SNPs

USP17A

Gene Sequence

>1593 bp
ATGGAGGACGACTCACTCTACTTGGGAGGTGAGTGGCAGTTCAACCACTTTTCAAAACTC
ACATCTTCTCGGCCAGATGCAGCTTTTGCTGAAATCCAGCGGACTTCTCTCCCTGAGAAG
TCACCACTTTCATGTGAGACCCGTGTCGACCTCTGTGACGATTTGGCTCCTGTGGCAAGA
CAGCTTGCTCCCAGGGAGAAGCTTCCTCTGAGTAGCAGGAGACCTGCTGCGGTGGGGGCT
GGGCTCCAGAATATGGGAAATACCTGCTACGTGAACGCTTCCTTGCAGTGCCTGACATAC
ACACCGCCCCTTGCCAACTACATGCTGTCCCGGGAGCACTCTCAAACGTGTCATCGTCAC
AAGGGCTGCATGCTCTGTACTATGCAAGCTCACATCACACGGGCCCTCCACAATCCTGGC
CACGTCATCCAGCCCTCACAGGCATTGGCTGCTGGCTTCCATAGAGGCAAGCAGGAAGAT
GCCCATGAATTTCTCATGTTCACTGTGGATGCCATGAAAAAGGCATGCCTTCCCGGGCAC
AAGCAGGTAGATCATCACTCTAAGGACACCACCCTCATCCACCAAATATTTGGAGGCTAC
TGGAGATCTCAAATCAAGTGTCTCCACTGCCACGGCATTTCAGACACTTTTGACCCTTAC
CTGGACATCGCCCTGGATATCCAGGCAGCTCAGAGTGTCCAGCAAGCTTTGGAACAGTTG
GTGAAGCCCGAAGAACTCAATGGAGAGAATGCCTATCATTGTGGTGTTTGTCTCCAGAGG
GCGTCGGCCTCCAAGACGTTAACTTTACACACCTCTGCCAAGGTCCTCATCCTTGTATTG
AAGAGATTCTCCGATGTCACAGGCAACAAGATTGCCAAGAATGTGCAATATCCTGAGTGC
CTTGACATGCAGCCATACATGTCTCAGCAGAACACAGGACCTCTTGTCTATGTCCTCTAT
GCTGTGCTGGTCCACGCTGGGTGGAGTTGTCACAACGGACATTACTTCTCTTATGTCAAA
GCTCAAGAAGGCCAGTGGTATAAAATGGATGATGCCGAGGTCACCGCCTCTAGCATCACT
TCTGTCCTGAGTCAACAGGCCTACGTCCTCTTTTACATCCAGAAGAGTGAATGGGAAAGA
CACAGTGAGAGTGTGTCAAGAGGCAGGGAACCAAGAGCCCTTGGCGCAGAAGACACAGAC
AGGCGAGCAACGCAAGGAGAGCTCAAGAGAGACCACCCCTGCCTCCAGGCCCCCGAGTTG
GACGAGCACTTGGTGGAAAGAGCCACTCAGGAAAGCACCTTAGACCACTGGAAATTCCTT
CAAGAGCAAAACAAAACGAAGCCTGAGTTCAACGTCAGAAAAGTCGAAGGTACCCTGCCT
CCCGACGTACTTGTGATTCATCAATCAAAATACAAGTGTGGGATGAAGAACCATCATCCT
GAACAGCAAAGCTCCCTGCTAAACCTCTCTTCGACGACACCGACACATCAGGAGTCCATG
AACACTGGCACACTCGCTTCCCTGCGAGGGAGGGCCAGGAGATCCAAAGGGAAGAACAAA
CACAGCAAGAGGGCTCTGCTTGTGTGCCAGTGA

Protein Properties

Number of Residues

530

Molecular Weight

59710.3

Theoretical pI

8.14

Pfam Domain Function

UCH (PF00443 )
HABP4_PAI-RBP1 (PF04774 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Ubiquitin carboxyl-terminal hydrolase 17
MEDDSLYLRGEWQFNHFSKLTSSRPDAAFAEIQRTSLPEKSPLSCETRVDLCDDLAPVAR
QLAPREKLPLSSRRPAAVGAGLQNMGNTCYVNASLQCLTYTPPLANYMLSREHSQTCHRH
KGCMLCTMQAHITRALHNPGHVIQPSQALAAGFHRGKQEDAHEFLMFTVDAMKKACLPGH
KQVDHHSKDTTLIHQIFGGYWRSQIKCLHCHGISDTFDPYLDIALDIQAAQSVQQALEQL
VKPEELNGENAYHCGVCLQRAPASKTLTLHTSAKVLILVLKRFSDVTGNKIAKNVQYPEC
LDMQPYMSQPNTGPLVYVLYAVLVHAGWSCHNGHYFSYVKAQEGQWYKMDDAEVTASSIT
SVLSQQAYVLFYIQKSEWERHSESVSRGREPRALGAEDTDRRATQGELKRDHPCLQAPEL
DEHLVERATQESTLDHWKFLQEQNKTKPEFNVRKVEGTLPPDVLVIHQSKYKCGMKNHHP
EQQSSLLNLSSSTPTHQESMNTGTLASLRGRARRSKGKNKHSKRALLVCQ

External Links

GenBank ID Protein

33333160

UniProtKB/Swiss-Prot ID

Q0WX57

UniProtKB/Swiss-Prot Entry Name

UBP17_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF544011

GeneCard ID