| Identification |
|---|
| HMDB Protein ID
| CDBP04673 |
| Secondary Accession Numbers
| Not Available |
| Name
| Glycylpeptide N-tetradecanoyltransferase |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| NMT1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in glycylpeptide N-tetradecanoyltransferase activity |
| Specific Function
| Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins |
| GO Classification
|
| Function |
| acyltransferase activity |
| n-acyltransferase activity |
| glycylpeptide n-tetradecanoyltransferase activity |
| catalytic activity |
| transferase activity |
| transferase activity, transferring acyl groups |
| transferase activity, transferring acyl groups other than amino-acyl groups |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein amino acid lipidation |
| macromolecule modification |
| protein modification process |
| n-terminal protein lipidation |
| n-terminal protein myristoylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 17q21.31 |
| SNPs
| NMT1 |
| Gene Sequence
|
>1485 bp
GACGAGAGTGAGACAGCAGTGAAGCCGCCGGCACCTCCGCTGCCGCAGATGATGGAAGGG
AACGGGAACGGCCATGAGCACTGCAGCGATTGCGAGAATGAGGAGGACAACAGCTACAAC
CGGGGTGGTTTGAGTCCAGCCAATGACACTGGAGCCAAAAAGAAGAAAAAGAAACAAAAA
AAGAAGAAAGAAAAAGGCAGTGAGACAGATTCAGCCCAGGATCAGCCTGTGAAGATGAAC
TCTTTGCCAGCAGAGAGGATCCAGGAAATACAGAAGGCCATTGAGCTGTTCTCAGTGGGT
CAGGGACCTGCCAAAACCATGGAGGAGGCTAGCAAGCGAAGCTACCAGTTCTGGGATACG
CAGCCCGTCCCCAAGCTGGGCGAAGTGGTGAACACCCATGGCCCCGTGGAGCCTGACAAG
GACAATATCCGCCAGGAGCCCTACACCCTGCCCCAGGGCTTCACCTGGGATGCTTTGGAC
CTGGGCGATCGTGGTGTGCTAAAAGAACTGTACACCCTCCTGAATGAGAACTATGTGGAA
GATGATGACAACATGTTCCGATTTGATTATTCCCCGGAGTTTCTTTTGTGGGCTCTCCGG
CCACCCGGCTGGCTCCCCCAGTGGCACTGTGGGGTTCGAGTGGTCTCAAGTCGGAAATTG
GTTGGGTTCATTAGCGCCATCCCAGCAAACATCCATATCTATGACACAGAGAAGAAGATG
GTAGAGATCAACTTCCTGTGTGTCCACAAGAAGCTGCGTTCCAAGAGGGTTGCTCCAGTT
CTGATCCGAGAGATCACCAGGCGGGTTCACCTGGAGGGCATCTTCCAAGCAGTTTACACT
GCCGGGGTGGTACTACCAAAGCCTGTTGGCACCTGCAGGTATTGGCATCGGTCCCTAAAC
CCACGGAAGCTGATTGAAGTGAAGTTCTCCCACCTGAGCAGAAATATGACCATGCAGCGC
ACCATGAAGCTCTACCGACTGCCAGAGACTCCCAAGACAGCTGGGCTGCGACCAATGGAA
ACAAAGGACATTCCAGTAGTGCACCAGCTCCTCACCAGGTACTTGAAGCAATTTCACCTT
ACGCCCGTCATGAGCCAGGAGGAGGTGGAGCACTGGTTCTACCCCCAGGAGAATATCATC
GACACTTTCGTGGTGGAGAACGCAAACGGAGAGGTGACAGATTTCCTGAGCTTTTATACG
CTGCCCTCCACCATCATGAACCATCCAACCCACAAGAGTCTCAAAGCTGCTTATTCTTTC
TACAACGTTCACACCCAGACCCCTCTTCTAGACCTCATGAGCGACGCCCTTGTCCTCGCC
AAAATGAAAGGGTTTGATGTGTTCAATGCACTGGATCTCATGGAGAACAAAACCTTCCTG
GAGAAGCTCAAGTTTGGCATAGGGGACGGCAACCTGCAGTATTACCTTTACAATTGGAAA
TGCCCCAGCATGGGGGCAGAGAAGGTTGGACTGGTGCTACAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 494 |
| Molecular Weight
| 56603.6 |
| Theoretical pI
| 7.91 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Glycylpeptide N-tetradecanoyltransferase
DESETAVKPPAPPLPQMMEGNGNGHEHCSDCENEEDNSYNRGGLSPANDTGAKKKKKKQK
KKKEKGSETDSAQDQPVKMNSLPAERIQEIQKAIELFSVGQGPAKTMEEASKRSYQFWDT
QPVPKLGEVVNTHGPVEPDKDNIRQEPYTLPQGFTWDALDLGDRGVLKELYTLLNENYVE
DDDNMFRFDYSPEFLLWALRPPGWLPQWHCGVRVVSSRKLVGFISAIPANIHIYDTEKKM
VEINFLCVHKKLRSKRVAPVLIREITRRVHLEGIFQAVYTAGVVLPKPVGTCRYWHRSLN
PRKLIEVKFSHLSRNMTMQRTMKLYRLPETPKTAGLRPMETKDIPVVHQLLTRYLKQFHL
TPVMSQEEVEHWFYPQENIIDTFVVENANGEVTDFLSFYTLPSTIMNHPTHKSLKAAYSF
YNVHTQTPLLDLMSDALVLAKMKGFDVFNALDLMENKTFLEKLKFGIGDGNLQYYLYNWK
CPSMGAEKVGLVLQ
|
| External Links |
|---|
| GenBank ID Protein
| 48257074 |
| UniProtKB/Swiss-Prot ID
| Q96HI4 |
| UniProtKB/Swiss-Prot Entry Name
| Q96HI4_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| BC008579 |
| GeneCard ID
| NMT1 |
| GenAtlas ID
| NMT1 |
| HGNC ID
| HGNC:7857 |
| References |
|---|
| General References
| Not Available |