| Identification |
|---|
| HMDB Protein ID
| CDBP04623 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ubiquitin carboxyl-terminal hydrolase 29 |
| Description
| Not Available |
| Synonyms
|
- Deubiquitinating enzyme 29
- Ubiquitin thiolesterase 29
- Ubiquitin-specific-processing protease 29
|
| Gene Name
| USP29 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ubiquitin thiolesterase activity |
| Specific Function
| Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal) |
| GO Classification
|
| Function |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| ubiquitin thiolesterase activity |
| thiolester hydrolase activity |
| Process |
| cellular macromolecule catabolic process |
| modification-dependent macromolecule catabolic process |
| modification-dependent protein catabolic process |
| ubiquitin-dependent protein catabolic process |
| metabolic process |
| catabolic process |
| macromolecule catabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 19q13.43 |
| SNPs
| USP29 |
| Gene Sequence
|
>2769 bp
ATGATATCTCTAAAGGTATGTGGATTCATCCAAATTTGGAGCCAGAAGACTGGGATGACT
AAGCTGAAAGAAGCTCTCATTGAAACAGTGCAAAGACAAAAGGAAATTAAACTGGTGGTC
ACTTTCAAATCTGGAAAATTTATAAGAATTTTTCAGCTGAGCAACAACATTAGAAGTGTG
GTCCTTAGACATTGTAAAAAAAGACAAAGTCACCTGCGTTTAACTTTGAAAAACAACGTG
TTCTTGTTTATTGACAAATTATCCTACAGAGATGCTAAACAGTTGAATATGTTCCTGGAC
ATAATCCACCAAAACAAATCTCAGCAACCCATGAAATCTGATGATGATTGGAGTGTGTTT
GAAAGCAGGAATATGCTGAAGGAAATTGACAAAACTTCATTTTACAGCATTTGTAACAAG
CCAAGTTATCAGAAGATGCCTTTGTTTATGTCAAAATCACCAACACATGTGAAAAAGGGG
ATATTAGAAAATCAAGGTGGGAAGGGGCAAAACACACTATCATCTGATGTACAGACAAAT
GAGGACATTCTGAAGGAAGATAACCCTGTACCAAACAAGAAATATAAGACAGATTCCTTG
AAATATATACAAAGCAATAGGAAGAACCCATCAAGTTTAGAGGATTTAGAAAAAGATAGA
GATTTGAAACTCGGGCCTTCATTCAATACCAACTGTAATGGAAATCCTAACCTAGATGAG
ACTGTTCTTGCAACCCAGACTCTCAATGCCAAAAATGGTTTGACATCTCCATTGGAACCA
GAGCACAGCCAGGGTGACCCAAGATGCAACAAAGCCCAGGTGCCTCTTGACTCTCATTCA
CAGCAACTGCAGCAGGGGTTCCCCAATTTGGGAAACACCTGTTACATGAATGCAGTTTTA
CAATCGCTATTTGCAATTCCATCTTTTGCTGATGACTTACTCACTCAAGGTGTCCCATGG
GAATATATTCCCTTTGAGGCTCTTATTATGACCTTGACCCAGCTGCTTGCTTTGAAAGAT
TTCTGTAGTACAAAGATCAAGAGAGAATTACTTGGGAATGTTAAAAAAGTCATTTCAGCA
GTTGCAGAAATATTTTCTGGCAACATGCAGAATGATGCTCATGAGTTTTTAGGTCAGTGT
TTAGACCAGCTGAAAGAAGACATGGAAAAATTAAATGCCACTTTGAATACTGGGAAAGAA
TGTGGGGATGAAAATTCATCTCCACAAATGCATGTTGGTAGTGCTGCCACCAAAGTGTTT
GTTTGCCCTGTTGTTGCTAATTTTGAGTTTGAATTGCAGCTCTCCCTTATTTGTAAAGCT
TGTGGTCATGCTGTTCTCAAGGTAGAACCTAATAATTATCTCTCCATCAACCTGCACCAA
GAAACAAAACCACTTCCTTTGTCCATTCAGAATTCTTTAGATCTTTTCTTTAAAGAAGAA
GAGCTTGAATATAACTGTCAGATGTGTAAGCAGAAGAGTTGTGTTGCAAGGCATACATTT
AGTAGGCTCTCCAGGGTCCTTATCATTCATCTGAAACGCTATAGCTTCAACAATGCTTGG
TTGCTGGTGAAGAATAACGAGCAAGTTTATATTCCCAAATCTTTAAGTTTATCTTCTTAT
TGCAATGAAAGCACCAAACCACCTCTTCCCTTGAGCAGTAGTGCACCTGTTGGGAAATGT
GAAGTCCTGGAAGTCTCTCAGGAGATGATTTCTGAGATCAACAGCCCATTGACACCATCA
ATGAAGCTGACCTCAGAATCCAGTGATTCCCTGGTTCTACCCGTTGAACCAGACAAGAAT
GCCGACCTACAAAGATTCCAGAGAGACTGTGGAGATGCAAGCCAAGAGCAGCATCAGAGA
GACCTGGAAAATGGCTCTGCACTAGAGTCAGAATTGGTCCACTTTAGAGATAGGGCAATC
GGTGAAAAGGAGCTTCCAGTGGCTGACTCACTGATGGACCAGGGAGACATTTCTCTTCCT
GTGATGTATGAAGATGGAGGGAAGCTGATCAGCAGCCCAGACACAAGGCTTGTCGAGGTT
CATCTTCAAGAGGTGCCTCAACATCCAGAACTTCAGAAGTATGAGAAAACCAATACATTC
GTAGAGTTCAATTTTGACAGTGTCACTGAGTCCACCAATGGCTTTTATGACTGTAAAGAA
AACAGGATTCCAGAAGGATCTCAAGGAATGGCTGAACAGCTCCAGCAGTGTATTGAGGAG
AGCATCATAGATGAATTTCTTCAGCAGGCACCACCTCCAGGTGTTAGGAAGCTGGATGCC
CAGGAACATACAGAAGAGACCCTCAATCAGTCTACAGAATTAAGACTTCAAAAGGCTGAC
CTGAATCACCTTGGGGCACTGGGTTCTGACAACCCAGGAAACAAAAACATTTTAGATGCA
GAGAACACAAGAGGTGAAGCCAAGGAACTAACAAGAAACGTGAAGATGGGGGATCCTCTC
CAGGCCTACAGACTCATCAGTGTTGTCAGCCATATCGGGAGCTCCCCAAATTCAGGCCAT
TACATCAGCGATGTGTATGACTTTCAGAAGCAGGCCTGGTTCACATACAACGATCTATGT
GTATCAGAAATCTCAGAGACCAAAATGCAGGAGGCGAGGCTTCACTCTGGGTATATCTTC
TTTTACATGCACAATGGGATTTTTGAGGAGCTGTTAAGAAAAGCAGAGAACTCTCGGCTA
CCTAGCACACAGGCAGGGGTGATCCCTCAGGGGGAATACGAAGGTGACTCTTTGTACAGA
CCTGCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 922 |
| Molecular Weight
| 104155.2 |
| Theoretical pI
| 5.74 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ubiquitin carboxyl-terminal hydrolase 29
MISLKVCGFIQIWSQKTGMTKLKEALIETVQRQKEIKLVVTFKSGKFIRIFQLSNNIRSV
VLRHCKKRQSHLRLTLKNNVFLFIDKLSYRDAKQLNMFLDIIHQNKSQQPMKSDDDWSVF
ESRNMLKEIDKTSFYSICNKPSYQKMPLFMSKSPTHVKKGILENQGGKGQNTLSSDVQTN
EDILKEDNPVPNKKYKTDSLKYIQSNRKNPSSLEDLEKDRDLKLGPSFNTNCNGNPNLDE
TVLATQTLNAKNGLTSPLEPEHSQGDPRCNKAQVPLDSHSQQLQQGFPNLGNTCYMNAVL
QSLFAIPSFADDLLTQGVPWEYIPFEALIMTLTQLLALKDFCSTKIKRELLGNVKKVISA
VAEIFSGNMQNDAHEFLGQCLDQLKEDMEKLNATLNTGKECGDENSSPQMHVGSAATKVF
VCPVVANFEFELQLSLICKACGHAVLKVEPNNYLSINLHQETKPLPLSIQNSLDLFFKEE
ELEYNCQMCKQKSCVARHTFSRLSRVLIIHLKRYSFNNAWLLVKNNEQVYIPKSLSLSSY
CNESTKPPLPLSSSAPVGKCEVLEVSQEMISEINSPLTPSMKLTSESSDSLVLPVEPDKN
ADLQRFQRDCGDASQEQHQRDLENGSALESELVHFRDRAIGEKELPVADSLMDQGDISLP
VMYEDGGKLISSPDTRLVEVHLQEVPQHPELQKYEKTNTFVEFNFDSVTESTNGFYDCKE
NRIPEGSQGMAEQLQQCIEESIIDEFLQQAPPPGVRKLDAQEHTEETLNQSTELRLQKAD
LNHLGALGSDNPGNKNILDAENTRGEAKELTRNVKMGDPLQAYRLISVVSHIGSSPNSGH
YISDVYDFQKQAWFTYNDLCVSEISETKMQEARLHSGYIFFYMHNGIFEELLRKAENSRL
PSTQAGVIPQGEYEGDSLYRPA
|
| External Links |
|---|
| GenBank ID Protein
| 9971757 |
| UniProtKB/Swiss-Prot ID
| Q9HBJ7 |
| UniProtKB/Swiss-Prot Entry Name
| UBP29_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF229438 |
| GeneCard ID
| USP29 |
| GenAtlas ID
| USP29 |
| HGNC ID
| HGNC:18563 |
| References |
|---|
| General References
| Not Available |