Showing Protein Ubiquitin carboxyl-terminal hydrolase 40 (CDBP04620)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 1 compounds
Identification
HMDB Protein ID CDBP04620
Secondary Accession Numbers Not Available
Name Ubiquitin carboxyl-terminal hydrolase 40
Description Not Available
Synonyms
  1. Deubiquitinating enzyme 40
  2. Ubiquitin thiolesterase 40
  3. Ubiquitin-specific-processing protease 40
Gene Name USP40
Protein Type Enzyme
Biological Properties
General Function Involved in ubiquitin thiolesterase activity
Specific Function May be catalytically inactive
GO Classification
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
ubiquitin thiolesterase activity
thiolester hydrolase activity
Process
metabolic process
catabolic process
macromolecule catabolic process
cellular macromolecule catabolic process
modification-dependent macromolecule catabolic process
modification-dependent protein catabolic process
ubiquitin-dependent protein catabolic process
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q37.1
SNPs USP40
Gene Sequence 
>3744 bp
ATGTCACTTTTTTTAAGGGTAGTATTTAGTTTCACAATGTTTGGGGACCTGTTTGAAGAG
GAGTATTCCACTGTGTCTAATAATCAGTATGGAAAAGGGAAGAAATTAAAGACTAAAGCT
TTGGAGCCACCTGCTCCTAGAGAATTCACCAATTTAAGCGGAATCAGAAATCAGGGTGGA
ACCTGTTACCTCAATTCCCTTCTTCAGACTCTTCATTTCACACCTGAATTCAGAGAAGCT
CTATTTTCTCTTGGCCCAGAAGAGCTTGGTTTGTTTGAAGATAAGGATAAACCCGATGCA
AAGGTTCGAATCATCCCTTTACAGTTACAGCGCTTGTTTGCTCAGCTTCTGCTCTTAGAC
CAGGAAGCTGCATCCACAGCAGACCTCACTGACAGCTTTGGGTGGACCAGTAATGAGGAA
ATGAGGCAACATGATGTGCAGGAACTGAATCGAATCCTCTTCAGCGCTTTGGAAACTTCT
TTAGTTGGGACCTCCGGTCATGACCTCATCTATCGTCTGTACCATGGAACCATTGTTAAC
CAGATTGTTTGTAAAGAATGTAAGAACGTTAGCGAGAGGCAGGAAGACTTCTTAGATCTA
ACAGTAGCAGTCAAAAATGTATCCGGTTTGGAAGATGCTCTCTGGAACATGTATGTAGAA
GAGGAAGTTTTTGATTGTGACAACTTGTACCACTGTGGAACTTGTGACAGGCTGGTTAAA
GCAGCAAAGTCGGCCAAATTACGTAAGCTGCCTCCTTTTCTTACTGTTTCATTACTAAGA
TTTAATTTTGATTTTGTGAAATGCGAACGCTACAAGGAAACTAGCTGTTATACATTCCCT
CTCCGGATTAATCTCAAGCCCTTTTGTGAACAGAGTGAATTGGATGACTTAGAATATATA
TATGACCTCTTCTCAGTTATTATACACAAAGGTGGCTGCTACGGAGGCCATTACCATGTA
TATATTAAAGATGTTGATCATTTGGGAAACTGGCAGTTTCAAGAGGAAAAAAGTAAACCA
GATGTGAATCTGAAAGATCTCCAGAGTGAAGAAGAGATTGATCATCCACTGATGATTCTA
AAAGCAATCTTATTAGAGGAGAATAATCTAATTCCTGTTGATCAGCTGGGCCAGAAACTT
TTGAAAAAGATAGGAATATCTTGGAACAAGAAGTACAGAAAACAGCATGGACCACTGCGG
AAGTTCTTACAGCTCCATTCTCAGATATTTCTACTCAGTTCAGATGAAAGTACAGTTCGT
CTCTTGAAGAATAGTTCTCTCCAGGCTGAGTCTGATTTCCAAAGGAATGACCAGCAAATT
TTCAAGATGCTTCCTCCAGAATCCCCAGGTTTAAACAATAGCATCTCCTGTCCCCACTGG
TTTGATATAAATGATTCTAAAGTCCAGCCAATCAGGGAAAAGGATATTGAACAGCAATTT
CAGGGTAAAGAAAGTGCCTACATGTTGTTTTATCGGAAATCCCAGTTGCAGAGACCCCCT
GAAGCTCGAGCTAATCCAAGATATGGGGTTCCATGTCATTTACTGAATGAAATGGATGCA
GCTAACATTGAACTGCAAACCAAAAGGGCAGAATGTGATTCTGCAAACAATACTTTTGAA
TTGCATCTTCACCTGGGCCCTCAGTATCATTTCTTCAATGGGGCTCTGCACCCAGTAGTC
TCTCAAACAGAAAGCGTGTGGGATTTGACCTTTGATAAAAGAAAAACTTTAGGAGATCTC
CGGCAGTCAATATTTCAGCTGTTAGAATTTTGGGAAGGAGACATGGTTCTTAGTGTTGCA
AAGCTTGTACCAGCAGGACTTCACATTTACCAGTCACTTGGCGGGGATGAACTGACACTG
TGTGAAACTGAAATTGCTGATGGGGAAGACATCTTTGTGTGGAATGGGGTGGAGGTTGGT
GGAGTCCACATTCAAACTGGTATTGACTGCGAACCTCTACTTTTAAATGTTCTTCATCTA
GACACAAGCAGTGATGGAGAAAAGTGTTGTCAGGTGATAGAATCTCCACATGTCTTTCCA
GCTAATGCAGAAGTGGGCACTGTCCTCACAGCCTTAGCAATCCCAGCAGGTGTCATCTTC
ATCAACAGTGCTGGATGTCCAGGTGGGGAGGGTTGGACGGCCATCCCCAAGGAAGACATG
AGGAAGACGTTCAGGGAGCAAGGGCTCAGAAATGGAAGCTCAATTTTAATTCAGGATTCT
CATGATGATAACAGCTTGTTGACCAAGGAAGAGAAATGGGTCACTAGTATGAATGAGATT
GACTGGCTCCACGTTAAAAATTTATGCCAGTTAGAATCTGAAGAGAAGCAAGTTAAAATA
TCAGCAACTGTTAACACAATGGTGTTTGATATTCGAATTAAAGCCATAAAGGAATTAAAA
TTAATGAAGGAACTAGCTGACAACAGCTGTTTGAGACCTATTGATAGAAATGGGAAGCTT
CTTTGTCCAGTGCCGGACAGCTATACTTTGAAGGAAGCAGAATTGAAGATGGGAAGTTCA
TTGGGACTGTGTCTTGGAAAAGCACCAAGTTCGTCTCAGTTGTTCCTGTTTTTTGCAATG
GGGAGTGACGTTCAACCTGGGACAGAAATGGAAATCGTAGTAGAAGAAACAATATCTGTG
AGAGATTGTTTAAAGTTAATGCTGAAGAAATCTGGCCTACAAGGAGATGCCTGGCATTTA
CGAAAAATGGATTGGTGCTATGAAGCTGGAGAGCCTTTATGTGAAGAAGATGCAACACTG
AAAGAACTTCTGATATGTTCTGGAGATACTTTGCTTTTAATTGAAGGACAACTTCCTCCT
CTGGGTTTCCTGAAGGTGCCCATCTGGTGGTACCAGCTTCAGGGTCCCTCAGGACACTGG
GAGAGTCATCAGGACCAGACCAACTGTACTTCGTCTTGGGGCAGAGTTTGGAGAGCCACT
TCCAGCCAAGGTGCTTCTGGGAACGAGCCTGCGCAAGTTTCTCTCCTCTACTTGGGAGAC
ATAGAGATCTCAGAAGATGCCACGCTGGCGGAGCTGAAGTCTCAGGCCATGACCTTGCCT
CCTTTCCTGGAGTTCGGTGTCCCGTCCCCAGCCCACCTCAGAGCCTGGACGGTGGAGAGG
AAGCGCCCAGGCAGGCTTTTACGAACTGACCGGCAGCCACTCAGGGAATATAAACTAGGA
CGGAGAATTGAGATCTGCTTAGAGCCCCTTCAGAAAGGCGAAAACTTGGGCCCCCAGGAC
GTGCTGCTGAGGACACAGGTGCGCATCCCTGGTGAGAGGACCTATGCCCCTGCCCTGGAC
CTGGTGTGGAACGCGGCCCAGGGTGGGACTGCCGGCTCCCTGAGGCAGAGAGTTGCCGAT
TTCTATCGTCTTCCCGTGGAGAAGATTGAAATTGCCAAATACTTTCCCGAAAAGTTCGAG
TGGCTTCCGATATCTAGCTGGAACCAACAAATAACCAAGAGGAAAAAGAAAAAAAAACAA
GATTATTTGCAAGGGGCACCGTATTACTTGAAAGACGGAGATACTATTGGTGTTAAGAAT
CTCCTGATTGACGACGATGATGATTTCAGTACAATCAGAGATGACACTGGAAAAGAAAAG
CAGAAACAACGGGCCCTGGGGAGAAGGAAAAGCCAAGAAGCCCTCCATGAGCAGAGCAGC
TACATCCTCTCCAGTGCAGAGACGCCTGCCCGGCCCCGAGCCCCGGAAACTTCTCTCTCC
ATCCACGTGGGGAGCTTCAGATAA
Protein Properties
Number of Residues 1235
Molecular Weight 140128.4
Theoretical pI 5.4
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Ubiquitin carboxyl-terminal hydrolase 40
MFGDLFEEEYSTVSNNQYGKGKKLKTKALEPPAPREFTNLSGIRNQGGTCYLNSLLQTLH
FTPEFREALFSLGPEELGLFEDKDKPDAKVRIIPLQLQRLFAQLLLLDQEAASTADLTDS
FGWTSNEEMRQHDVQELNRILFSALETSLVGTSGHDLIYRLYHGTIVNQIVCKECKNVSE
RQEDFLDLTVAVKNVSGLEDALWNMYVEEEVFDCDNLYHCGTCDRLVKAAKSAKLRKLPP
FLTVSLLRFNFDFVKCERYKETSCYTFPLRINLKPFCEQSELDDLEYIYDLFSVIIHKGG
CYGGHYHVYIKDVDHLGNWQFQEEKSKPDVNLKDLQSEEEIDHPLMILKAILLEENNLIP
VDQLGQKLLKKIGISWNKKYRKQHGPLRKFLQLHSQIFLLSSDESTVRLLKNSSLQAESD
FQRNDQQIFKMLPPESPGLNNSISCPHWFDINDSKVQPIREKDIEQQFQGKESAYMLFYR
KSQLQRPPEARANPRYGVPCHLLNEMDAANIELQTKRAECDSANNTFELHLHLGPQYHFF
NGALHPVVSQTESVWDLTFDKRKTLGDLRQSIFQLLEFWEGDMVLSVAKLVPAGLHIYQS
LGGDELTLCETEIADGEDIFVWNGVEVGGVHIQTGIDCEPLLLNVLHLDTSSDGEKCCQV
IESPHVFPANAEVGTVLTALAIPAGVIFINSAGCPGGEGWTAIPKEDMRKTFREQGLRNG
SSILIQDSHDDNSLLTKEEKWVTSMNEIDWLHVKNLCQLESEEKQVKISATVNTMVFDIR
IKAIKELKLMKELADNSCLRPIDRNGKLLCPVPDSYTLKEAELKMGSSLGLCLGKAPSSS
QLFLFFAMGSDVQPGTEMEIVVEETISVRDCLKLMLKKSGLQGDAWHLRKMDWCYEAGEP
LCEEDATLKELLICSGDTLLLIEGQLPPLGFLKVPIWWYQLQGPSGHWESHQDQTNCTSS
WGRVWRATSSQGASGNEPAQVSLLYLGDIEISEDATLAELKSQAMTLPPFLEFGVPSPAH
LRAWTVERKRPGRLLRTDRQPLREYKLGRRIEICLEPLQKGENLGPQDVLLRTQVRIPGE
RTYAPALDLVWNAAQGGTAGSLRQRVADFYRLPVEKIEIAKYFPEKFEWLPISSWNQQIT
KRKKKKKQDYLQGAPYYLKDGDTIGVKNLLIDDDDDFSTIRDDTGKEKQKQRALGRRKSQ
EALHEQSSYILSSAETPARPRAPETSLSIHVGSFR
GenBank ID Protein 41055953
UniProtKB/Swiss-Prot ID Q9NVE5
UniProtKB/Swiss-Prot Entry Name UBP40_HUMAN
PDB IDs Not Available
GenBank Gene ID Not Available
GeneCard ID USP40
GenAtlas ID USP40
HGNC ID HGNC:20069
References
General References Not Available