Cannabis Compound Database: Showing Protein Ubiquitin carboxyl-terminal hydrolase 51 (CDBP04616)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP04616

Secondary Accession Numbers

Not Available

Name

Ubiquitin carboxyl-terminal hydrolase 51

Description

Not Available

Synonyms

Deubiquitinating enzyme 51
Ubiquitin thiolesterase 51
Ubiquitin-specific-processing protease 51

Gene Name

USP51

Protein Type

Enzyme

Biological Properties

General Function

Involved in ubiquitin thiolesterase activity

Specific Function

Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C- terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal)

GO Classification

Function
thiolester hydrolase activity
ion binding
cation binding
metal ion binding
hydrolase activity, acting on ester bonds
binding
catalytic activity
hydrolase activity
transition metal ion binding
zinc ion binding
ubiquitin thiolesterase activity
Process
metabolic process
catabolic process
macromolecule catabolic process
cellular macromolecule catabolic process
modification-dependent macromolecule catabolic process
modification-dependent protein catabolic process
ubiquitin-dependent protein catabolic process

Cellular Location

Cytoplasmic

Pathways

Not Available

Gene Properties

Chromosome Location

Not Available

Locus

Not Available

SNPs

USP51

Gene Sequence

>2136 bp
ATGGCCCAGGTTCGAGAAACTTCTTTGCCCTCCGGCTCTGGGGTCCGCTGGATCTCCGGA
GGTGGGGGAGGAGCCTCTCCTGAGGAGGCGGTTGAGAAGGCGGGGAAAATGGAGGAGGCG
GCGGCGGGGGCTACGAAGGCGTCTTCGAGACGTGAAGCCGAGGAGATGAAGCTGGAGCCA
TTACAAGAGCGTGAGCCCGCGCCGGAGGAGAACTTGACGTGGAGCAGCAGCGGCGGCGAC
GAGAAGGTGCTCCCTTCAATCCCCCTTCGCTGTCACAGCAGCTCCTCGCCCGTTTGCCCG
CGCCGCAAGCCCCGCCCTCGGCCCCAGCCCCGGGCCCGCTCCCGCAGCCAGCCTGGGCTC
TCGGCCCCACCCCCGCCTCCAGCCCGGCCCCCGCCCCCGCCGCCACCCCCGCCCCCACCC
GCACCGCGGCCCAGGGCCTGGCGTGGATCCCGGCGCAGATCCCGGCCTGGGTCCAGGCCT
CAGACACGGAGAAGCTGCTCTGGTGACCTAGACGGGTCGGGGGATCCTGGCGGCTTAGGG
GACTGGTTGCTGGAGGTCGAGTTTGGTCAGGGTCCCACAGGCTGCTCTCATGTGGAGAGC
TTTAAAGTAGGTAAGAACTGGCAGAAGAACCTGAGGTTGATCTACCAGCGTTTCGTTTGG
AGTGGGACCCCAGAGACTAGGAAACGTAAAGCAAAGTCATGCATCTGTCACGTATGTAGT
ACCCATATGAACAGACTCCACTCTTGTCTCTCCTGTGTCTTTTTTGGCTGCTTCACTGAG
AAACATATTCACAAACATGCAGAAACAAAGCAGCACCATTTAGCTGTAGACCTTTATCAT
GGGGTCATATATTGCTTCATGTGTAAGGATTATGTATATGACAAAGACATAGAACAGATT
GCCAAAGAAACAAAAGAAAAAATTTTGAGATTATTAACTTCCACCTCAACAGATGTTTCT
CATCAACAGTTTATGACATCAGGGTTTGAAGACAAGCAATCAACCTGTGAGACAAAGGAA
CAGGAGCCAAAATTGGTGAAACCCAAGAAAAAGAGAAGAAAAAAGTCAGTCTATACTGTA
GGCCTGAGAGGGCTAATCAATCTTGGGAACACTTGTTTTATGAATTGTATTGTCCAGGCA
CTTACCCATATTCCTCTACTGAAAGATTTCTTCCTCTCTGACAAGCACAAATGTATAATG
ACAAGCCCCAGCTTGTGTCTGGTCTGTGAAATGTCTTCGCTTTTTCATGCTATGTACTCT
GGGAGCCGAACTCCTCACATTCCCTATAAGTTACTGCATCTGATATGGATCCATGCAGAA
CATTTAGCAGGGTACAGGCAGCAGGATGCCCATGAGTTCCTTATTGCAATATTAGACGTG
CTACATAGACACAGCAAAGATGATAGTGGTGGGCAGGAGGCCAATAACCCCAACTGCTGT
AACTGCATCATAGACCAAATCTTTACAGGTGGCCTGCAATCAGATGTCACATGTCAAGCC
TGCCATAGTGTTTCTACCACCATAGACCCATGCTGGGACATCAGTTTGGACTTGCCTGGC
TCTTGTGCCACATTCGATTCCCAGAACCCAGAGAGGGCTGACAGCACAGTGAGCAGGGAT
GACCACATACCAGGAATCCCCTCACTTACAGACTGTCTACAGTGGTTTACAAGGCCAGAG
CACCTAGGAAGCAGTGCCAAAATCAAATGCAATAGTTGCCAAAGCTACCAGGAGTCTACT
AAACAGCTCACAATGAAAAAATTACCCATTGTGGCTTGTTTTCATCTCAAGCGGTTTGAG
CATGTAGGCAAACAGAGGCGAAAGATTAATACCTTTATCTCCTTTCCCTTGGAGCTGGAC
ATGACTCCGTTTTTGGCCTCTACTAAAGAGAGCAGAATGAAAGAAGGCCAGCCACCAACA
GATTGTGTGCCCAATGAGAATAAGTATTCCTTGTTTGCAGTGATTAATCACCATGGAACT
TTGGAAAGTGGCCACTATACCAGCTTCATCCGGCAACAAAAGGACCAGTGGTTCAGCTGT
GATGATGCCATCATCACCAAGGCTACCATTGAGGACTTACTCTACAGTGAAGGGTATTTA
CTGTTCTATCACAAACAGGGTCTAGAGAAAGACTAG

Protein Properties

Number of Residues

711

Molecular Weight

79755.2

Theoretical pI

8.44

Pfam Domain Function

UCH (PF00443 )
zf-UBP (PF02148 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Ubiquitin carboxyl-terminal hydrolase 51
MAQVRETSLPSGSGVRWISGGGGGASPEEAVEKAGKMEEAAAGATKASSRREAEEMKLEP
LQEREPAPEENLTWSSSGGDEKVLPSIPLRCHSSSSPVCPRRKPRPRPQPRARSRSQPGL
SAPPPPPARPPPPPPPPPPPAPRPRAWRGSRRRSRPGSRPQTRRSCSGDLDGSGDPGGLG
DWLLEVEFGQGPTGCSHVESFKVGKNWQKNLRLIYQRFVWSGTPETRKRKAKSCICHVCS
THMNRLHSCLSCVFFGCFTEKHIHKHAETKQHHLAVDLYHGVIYCFMCKDYVYDKDIEQI
AKETKEKILRLLTSTSTDVSHQQFMTSGFEDKQSTCETKEQEPKLVKPKKKRRKKSVYTV
GLRGLINLGNTCFMNCIVQALTHIPLLKDFFLSDKHKCIMTSPSLCLVCEMSSLFHAMYS
GSRTPHIPYKLLHLIWIHAEHLAGYRQQDAHEFLIAILDVLHRHSKDDSGGQEANNPNCC
NCIIDQIFTGGLQSDVTCQACHSVSTTIDPCWDISLDLPGSCATFDSQNPERADSTVSRD
DHIPGIPSLTDCLQWFTRPEHLGSSAKIKCNSCQSYQESTKQLTMKKLPIVACFHLKRFE
HVGKQRRKINTFISFPLELDMTPFLASTKESRMKEGQPPTDCVPNENKYSLFAVINHHGT
LESGHYTSFIRQQKDQWFSCDDAIITKATIEDLLYSEGYLLFYHKQGLEKD

External Links

GenBank ID Protein

40788183

UniProtKB/Swiss-Prot ID

Q70EK9

UniProtKB/Swiss-Prot Entry Name

UBP51_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AJ583823

GeneCard ID