Identification |
HMDB Protein ID
| CDBP04603 |
Secondary Accession Numbers
| Not Available |
Name
| Protein tyrosine phosphatase domain-containing protein 1 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| PTPDC1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in phosphatase activity |
Specific Function
| Not Available |
GO Classification
|
Function |
phosphoprotein phosphatase activity |
protein tyrosine phosphatase activity |
hydrolase activity, acting on ester bonds |
catalytic activity |
hydrolase activity |
phosphoric ester hydrolase activity |
phosphatase activity |
protein tyrosine/serine/threonine phosphatase activity |
Process |
protein amino acid dephosphorylation |
metabolic process |
cellular metabolic process |
phosphorus metabolic process |
phosphate metabolic process |
dephosphorylation |
|
Cellular Location
|
- Cytoplasmic
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:9 |
Locus
| 9q22.32 |
SNPs
| PTPDC1 |
Gene Sequence
|
>2265 bp
ATGGCTGCAGGAGTCTTGCCTCAGAATGAACAACCATATTCTACCTTGGTGAATAACAGC
GAGTGTGTTGCAAACATGAAAGGAAATTTAGAACGTCCAACACCAAAGTACACAAAAGTA
GGGGAGCGTTTACGGCATGTCATTCCTGGACACATGGCATGTTCCATGGCGTGTGGCGGT
AGAGCTTGCAAGTATGAGAACCCAGCCCGCTGGAGTGAGCAGGAGCAAGCCATTAAGGGG
GTTTACTCATCCTGGGTCACTGATAATATACTGGCCATGGCCCGCCCATCCTCTGAGCTC
CTGGAGAAGTACCACATCATTGATCAGTTCCTCAGCCATGGCATAAAAACAATAATCAAC
CTCCAGCGCCCTGGTGAGCATGCTAGCTGTGGGAACCCTCTGGAACAAGAAAGTGGCTTC
ACATACCTTCCTGAGGCTTTCATGGAGGCTGGCATTTACTTCTACAATTTCGGATGGAAG
GATTATGGTGTAGCGTCTCTTACTACTATCCTAGATATGGTGAAGGTGATGACATTTGCC
TTACAGGAAGGAAAAGTAGCTATCCATTGTCATGCAGGGCTTGGTCGAACAGGTGTTTTA
ATAGCCTGTTACTTAGTTTTTGCAACGAGAATGACTGCTGACCAAGCAATTATATTTGTG
CGGGCAAAGCGACCCAATTCCATACAAACCAGAGGACAGCTCCTCTGTGTAAGGGAATTT
ACTCAGTTTCTAACTCCTCTCCGCAATATATTCTCTTGCTGTGATCCCAAAGCACATGCT
GTCACCTTACCTCAATATCTAATTCGCCAGCGTCATCTGCTTCATGGTTATGAGGCACGA
CTTCTGAAACACGTGCCAAAAATTATCCACCTAGTTTGCAAATTGCTGCTGGACTTAGCG
GAGAACAGGCCAGTGATGATGAAGGATGTGTCCGAAGGACCTGGTCTCTCTGCTGAAATA
GAAAAGACAATGTCTGAGATGGTCACCATGCAGCTGGATAAAGAGTTACTGAGGCATGAC
AGTGATGTGTCCAACCCGCCTAACCCCACTGCAGTGGCAGCAGATTTTGACAATCGAGGC
ATGATTTTCTCCAATGAGCAACAGTTTGACCCTCTTTGGAAAAGGCGGAATGTTGAGTGC
CTTCAACCCCTGACTCATCTGAAAAGGCGGCTCAGCTACAGTGACTCAGATTTAAAGAGG
GCCGAGAACCTCCTGGAGCAAGGGGAGACTCCACAGACAGTGCCTGCCCAGATCTTGGTT
GGCCACAAGCCCAGGCAGCAGAAGCTCATAAGCCATTGTTACATCCCACAGTCTCCAGAA
CCAGACTTACACAAGGAAGCCTTGGTTCGCAGCACACTTTCTTTCTGGAGTCAGTCAAAG
TTTGGAGGCCTGGAAGGACTCAAAGATAATGGGTCACCAATTTTCCATGGAAGGATCATT
CCAAAGGAAGCACAGCAGAGTGGAGCTTTCTCTGCAGATGTTTCAGGCTCACACAGCCCT
GGGGAGCCAGTTTCACCCAGCTTTGCAAATGTCCATAAGGATCCAAACCCTGCTCACCAG
CAAGTGTCTCACTGTCAGTGTAAAACTCATGGTGTTGGGAGCCCTGGCTCTGTCAGGCAG
AACAGCAGGACACCCCGAAGCCCTCTGGACTGTGGCTCCAGTCCCAAAGCACAGTTCTTG
GTTGAACATGAAACCCAGGACAGTAAAGATCTGTCTGAAGCAGCTTCACACTCTGCATTA
CAGTCTGAATTGAGTGCTGAGGCAAGAAGAATACTGGCGGCCAAAGCCCTAGCAAATTTA
AATGAATCTGTAGAAAAGGAGGAACTAAAAAGGAAGGTAGAAATGTGGCAGAAAGAGCTT
AATTCCCGAGATGGAGCTTGGGAAAGAATATGTGGCGAGAGGGACCCTTTCATCCTATGC
AGCTTGATGTGGTCTTGGGTGGAGCAACTGAAGGAGCCTGTAATCACCAAAGAGGATGTG
GACATGTTGGTTGACAGGCGAGCAGATGCCGCAGAAGCACTTTTTTTATTAGAGAAGGGA
CAGCACCAGACTATTCTCTGCGTGTTGCACTGCATAGTGAACCTGCAGACAATTCCCGTG
GATGTGGAGGAAGCTTTCCTTGCCCATGCCATTAAGGCATTCACTAAGGTTAATTTTGAT
TCTGAAAATGGACCAACAGTTTACAACACCCTGAAGAAAATATTTAAGCACACGCTGGAA
GAAAAAAGAAAAATGACAAAAGATGGCCCTAAGCCTGGCCTCTAG
|
Protein Properties |
Number of Residues
| 754 |
Molecular Weight
| 84456.0 |
Theoretical pI
| 7.57 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Protein tyrosine phosphatase domain-containing protein 1
MAAGVLPQNEQPYSTLVNNSECVANMKGNLERPTPKYTKVGERLRHVIPGHMACSMACGG
RACKYENPARWSEQEQAIKGVYSSWVTDNILAMARPSSELLEKYHIIDQFLSHGIKTIIN
LQRPGEHASCGNPLEQESGFTYLPEAFMEAGIYFYNFGWKDYGVASLTTILDMVKVMTFA
LQEGKVAIHCHAGLGRTGVLIACYLVFATRMTADQAIIFVRAKRPNSIQTRGQLLCVREF
TQFLTPLRNIFSCCDPKAHAVTLPQYLIRQRHLLHGYEARLLKHVPKIIHLVCKLLLDLA
ENRPVMMKDVSEGPGLSAEIEKTMSEMVTMQLDKELLRHDSDVSNPPNPTAVAADFDNRG
MIFSNEQQFDPLWKRRNVECLQPLTHLKRRLSYSDSDLKRAENLLEQGETPQTVPAQILV
GHKPRQQKLISHCYIPQSPEPDLHKEALVRSTLSFWSQSKFGGLEGLKDNGSPIFHGRII
PKEAQQSGAFSADVSGSHSPGEPVSPSFANVHKDPNPAHQQVSHCQCKTHGVGSPGSVRQ
NSRTPRSPLDCGSSPKAQFLVEHETQDSKDLSEAASHSALQSELSAEARRILAAKALANL
NESVEKEELKRKVEMWQKELNSRDGAWERICGERDPFILCSLMWSWVEQLKEPVITKEDV
DMLVDRRADAAEALFLLEKGQHQTILCVLHCIVNLQTIPVDVEEAFLAHAIKAFTKVNFD
SENGPTVYNTLKKIFKHTLEEKRKMTKDGPKPGL
|
External Links |
GenBank ID Protein
| 30089950 |
UniProtKB/Swiss-Prot ID
| A2A3K4 |
UniProtKB/Swiss-Prot Entry Name
| PTPC1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_177995.1 |
GeneCard ID
| PTPDC1 |
GenAtlas ID
| PTPDC1 |
HGNC ID
| HGNC:30184 |
References |
General References
| Not Available |