Identification |
HMDB Protein ID
| CDBP04596 |
Secondary Accession Numbers
| Not Available |
Name
| Carboxypeptidase B |
Description
| Not Available |
Synonyms
|
- PASP
- Pancreas-specific protein
|
Gene Name
| CPB1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in metallocarboxypeptidase activity |
Specific Function
| Preferential release of a C-terminal lysine or arginine amino acid |
GO Classification
|
Function |
transition metal ion binding |
zinc ion binding |
metallocarboxypeptidase activity |
carboxypeptidase activity |
peptidase activity |
peptidase activity, acting on l-amino acid peptides |
exopeptidase activity |
ion binding |
cation binding |
metal ion binding |
binding |
catalytic activity |
hydrolase activity |
Process |
metabolic process |
macromolecule metabolic process |
protein metabolic process |
proteolysis |
|
Cellular Location
|
- Secreted
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:3 |
Locus
| 3q24 |
SNPs
| CPB1 |
Gene Sequence
|
>1254 bp
ATGTTGGCACTCTTGGTTCTGGTGACTGTGGCCCTGGCATCTGCTCATCATGGTGGTGAG
CACTTTGAAGGCGAGAAGGTGTTCCGTGTTAACGTTGAAGATGAAAATCACATTAACATA
ATCCGCGAGTTGGCCAGCACGACCCAGATTGACTTCTGGAAGCCAGATTCTGTCACACAA
ATCAAACCTCACAGTACAGTTGACTTCCGTGTTAAAGCAGAAGATACTGTCACTGTGGAG
AATGTTCTAAAGCAGAATGAACTACAATACAAGGTACTGATAAGCAACCTGAGAAATGTG
GTGGAGGCTCAGTTTGATAGCCGGGTTCGTGCAACAGGACACAGTTATGAGAAGTACAAC
AAGTGGGAAACGATAGAGGCTTGGACTCAACAAGTCGCCACTGAGAATCCAGCCCTCATC
TCTCGCAGTGTTATCGGAACCACATTTGAGGGACGCGCTATTTACCTCCTGAAGGTTGGC
AAAGCTGGACAAAATAAGCCTGCCATTTTCATGGACTGTGGTTTCCATGCCAGAGAGTGG
ATTTCTCCTGCATTCTGCCAGTGGTTTGTAAGAGAGGCTGTTCGTACCTATGGACGTGAG
ATCCAAGTGACAGAGCTTCTCAACAAGTTAGACTTTTATGTCCTGCCTGTGCTCAATATT
GATGGCTACATCTACACCTGGACCAAGAGCCGATTTTGGAGAAAGACTCGCTCCACCCAT
ACTGGATCTAGCTGCATTGGCACAGACCCCAACAGAAATTTTGATGCTGGTTGGTGTGAA
ATTGGAGCCTCTCGAAACCCCTGTGATGAAACTTACTGTGGACCTGCCGCAGAGTCTGAA
AAGGAGACCAAGGCCCTGGCTGATTTCATCCGCAACAAACTCTCTTCCATCAAGGCATAT
CTGACAATCCACTCGTACTCCCAAATGATGATCTACCCTTACTCATATGCTTACAAACTC
GGTGAGAACAATGCTGAGTTGAATGCCCTGGCTAAAGCTACTGTGAAAGAACTTGCCTCA
CTGCACGGCACCAAGTACACATATGGCCCGGGAGCTACAACAATCTATCCTGCTGCTGGG
GGCTCTGACGACTGGGCTTATGACCAAGGAATCAGATATTCCTTCACCTTTGAACTTCGA
GATACAGGCAGATATGGCTTTCTCCTTCCAGAATCCCAGATCCGGGCTACCTGCGAGGAG
ACCTTCCTGGCAATCAAGTATGTTGCCAGCTACGTCCTGGAACACCTGTACTAG
|
Protein Properties |
Number of Residues
| 417 |
Molecular Weight
| 47367.1 |
Theoretical pI
| 6.59 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Carboxypeptidase B
MLALLVLVTVALASAHHGGEHFEGEKVFRVNVEDENHINIIRELASTTQIDFWKPDSVTQ
IKPHSTVDFRVKAEDTVTVENVLKQNELQYKVLISNLRNVVEAQFDSRVRATGHSYEKYN
KWETIEAWTQQVATENPALISRSVIGTTFEGRAIYLLKVGKAGQNKPAIFMDCGFHAREW
ISPAFCQWFVREAVRTYGREIQVTELLDKLDFYVLPVLNIDGYIYTWTKSRFWRKTRSTH
TGSSCIGTDPNRNFDAGWCEIGASRNPCDETYCGPAAESEKETKALADFIRNKLSSIKAY
LTIHSYSQMMIYPYSYAYKLGENNAELNALAKATVKELASLHGTKYTYGPGATTIYPAAG
GSDDWAYDQGIRYSFTFELRDTGRYGFLLPESQIRATCEETFLAIKYVASYVLEHLY
|
External Links |
GenBank ID Protein
| 2960072 |
UniProtKB/Swiss-Prot ID
| P15086 |
UniProtKB/Swiss-Prot Entry Name
| CBPB1_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AJ224866 |
GeneCard ID
| CPB1 |
GenAtlas ID
| CPB1 |
HGNC ID
| HGNC:2299 |
References |
General References
| Not Available |