Identification
HMDB Protein ID CDBP04581
Secondary Accession Numbers Not Available
Name Vacuolar-type H(+)-ATPase
Description Not Available
Synonyms Not Available
Gene Name Not Available
Protein Type Enzyme
Biological Properties
General Function Involved in hydrogen ion transmembrane transporter activity
Specific Function Not Available
GO Classification
Component
macromolecular complex
protein complex
proton-transporting two-sector atpase complex, proton-transporting domain
Function
transporter activity
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
cation transmembrane transporter activity
inorganic cation transmembrane transporter activity
monovalent inorganic cation transmembrane transporter activity
hydrogen ion transmembrane transporter activity
Process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
atp synthesis coupled proton transport
atp biosynthetic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Not Available
Locus Not Available
SNPs Not Available
Gene Sequence
>2496 bp
ATGGGGGAGCTTTTCCGGAGTGAAGAAATGACACTGGCCCAGCTTTTTCTACAGTCAGAG
GCTGCTTATTGTTGTGTCAGTGAATTAGGAGAACTTGGAAAGGTTCAGTTTCGTGACTTA
AATCCAGATGTGAATGTTTTCCAACGGAAATTTGTGAATGAAGTTAGAAGATGTGAAGAA
ATGGATCGAAAGCTTCGATTTGTTGAGAAAGAGATAAGAAAAGCTAACATTCCGATTATG
GACACCGGTGAAAACCCAGAGGTTCCCTTCCCCCGGGACATGATCGACTTAGAGGCCAAT
TTTGAGAAGATTGAAAATGAACTGAAGGAAATCAACACAAACCAGGAAGCTCTGAAGAGA
AACTTCCTGGAACTGACCGAATTAAAATTTATACTTCGCAAAACTCAGCAATTTTTTGAT
GAGATGGCGGATCCAGACTTGTTGGAAGAGTCCTCATCCCTCTTGGAGCCAAGTGAGATG
GGAAGAGGCACTCCTTTAAGACTTGGCTTCGTGGCTGGTGTCATTAACCGGGAGCGCATC
CCTACTTTTGAGCGCATGCTTTGGCGGGTATGCCGGGGAAATGTGTTCCTGCGACAGGCT
GAAATCGAGAACCCCCTGGAGGATCCTGTGACTGGCGACTACGTGCACAAGTCTGTGTTT
ATCATTTTCTTCCAAGGCGATCAGCTGAAAAACAGAGTCAAGAAAATCTGTGAAGGGTTC
CGAGCCTCACTCTATCCCTGTCCTGAGACACCACAGGAGAGGAAGGAAATGGCTTCTGGA
GTGAATACCAGGATTGATGATCTCCAAATGGTTCTGAATCAAACGGAGGATCACCGCCAG
AGGGTTCTGCAGGCAGCTGCTAAGAACATCCGTGTCTGGTTCATCAAAGTGCGGAAGATG
AAGGCCATCTATCACACCCTGAACCTGTGCAACATAGATGTGACTCAGAAATGCTTGATT
GCAGAGGTCTGGTGCCCTGTCACCGACCTTGACTCCATCCAGTTTGCACTCAGAAGGGGC
ACGGAACACAGTGGTTCCACTGTACCTTCCATTTTGAACAGGATGCAGACAAACCAGACT
CCCCCAACCTATAACAAAACCAACAAGTTTACCTATGGCTTTCAGAACATAGTAGATGCT
TATGGAATTGGAACTTACCGAGAGATAAATCCAGCTCCGTATACTATTATCACGTTCCCT
TTTCTATTTGCTGTGATGTTTGGAGACTTCGGTCATGGCATTTTAATGACCCTTTTTGCT
GTGTGGATGGTACTGAGGGAGAGCCGGATCCTTTCCCAGAAGAATGAGAATGAGATGTTT
AGCACTGTGTTCAGTGGTCGATACATTATTTTATTGATGGGTGTGTTCTCCATGTACACT
GGCCTCATCTACAATGATTGCTTTTCCAAGTCTCTTAATATCTTTGGGTCATCCTGGAGT
GTACGGCCGATGTTTACTTATAATTGGACTGAAGAGACGCTTCGGGGGAACCCTGTTCTA
CAGCTGAACCCAGCCCTCCCTGGAGTGTTTGGTGGACCATACCCTTTTGGCATTGATCCA
ATTTGGAACATTGCTACCAATAAACTGACGTTCTTGAACTCCTTTAAGATGAAGATGTCT
GTTATCCTTGGTATCATCCATATGCTGTTTGGAGTCAGCCTGAGTCTGTTCAACCATATC
TATTTCAAGAAGCCCCTGAATATCTACTTTGGATTTATTCCTGAAATAATCTTCATGACC
TCTTTGTTTGGCTATTTGGTTATCCTTATTTTTTACAAGTGGACGGCCTATGATGCTCAT
ACCTCTGAGAATGCACCAAGCCTTCTGATCCATTTCATAAACATGTTCCTCTTTTCCTAC
CCAGAGTCTGGTTATTCAATGTTGTATTCTGGACAGAAAGGAATTCAGTGTTTCCTGGTA
GTGGTTGCACTACTGTGTGTACCTTGGATGCTGCTGTTTAAACCATTGGTCCTTCGCCGT
CAGTATTTGAGGAGAAAGCATTTGGGAACTCTCAACTTTGGTGGGATCAGGGTGGGCAAC
GGACCGACAGAGGAGGATGCTGAGATTATTCAGCATGACCAGCTCTCCACCCACTCAGAG
GACGCAGACGAGTTTGACTTTGGGGACACCATGGTCCACCAGGCCATCCACACCATCGAG
TACTGCCTGGGCTGCATCTCCAACACTGCCTCCTACTTGCGGCTCTGGGCCCTCAGCCTC
GCTCATGCGCACGTGTCTGAGGTGCTTTGGACCATGGTGATCCACATCGGCCTGAGCGTG
AAGAGCTTGGCGGGAGGTTTGGTGCTGTTCTTCTTCTTCACTGCCTTTGCCACCCTGACC
GTGGCCATCCTCCTGATCATGGAGGGCCTCTCGGCCTTTCTCCACGCACTGCGCTTACAC
TGGGTTGAGTTCCAGAATAAATTCTACAGCGGGACCGGTTTCAAGTTCTTACCCTTCTCC
TTCGAGCATATTCGGGAAGGGAAGTTTGAAGAGTGA
Protein Properties
Number of Residues 831
Molecular Weight 95750.3
Theoretical pI 6.67
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Vacuolar-type H(+)-ATPase
MGELFRSEEMTLAQLFLQSEAAYCCVSELGELGKVQFRDLNPDVNVFQRKFVNEVRRCEE
MDRKLRFVEKEIRKANIPIMDTGENPEVPFPRDMIDLEANFEKIENELKEINTNQEALKR
NFLELTELKFILRKTQQFFDEMADPDLLEESSSLLEPSEMGRGTPLRLGFVAGVINRERI
PTFERMLWRVCRGNVFLRQAEIENPLEDPVTGDYVHKSVFIIFFQGDQLKNRVKKICEGF
RASLYPCPETPQERKEMASGVNTRIDDLQMVLNQTEDHRQRVLQAAAKNIRVWFIKVRKM
KAIYHTLNLCNIDVTQKCLIAEVWCPVTDLDSIQFALRRGTEHSGSTVPSILNRMQTNQT
PPTYNKTNKFTYGFQNIVDAYGIGTYREINPAPYTIITFPFLFAVMFGDFGHGILMTLFA
VWMVLRESRILSQKNENEMFSTVFSGRYIILLMGVFSMYTGLIYNDCFSKSLNIFGSSWS
VRPMFTYNWTEETLRGNPVLQLNPALPGVFGGPYPFGIDPIWNIATNKLTFLNSFKMKMS
VILGIIHMLFGVSLSLFNHIYFKKPLNIYFGFIPEIIFMTSLFGYLVILIFYKWTAYDAH
TSENAPSLLIHFINMFLFSYPESGYSMLYSGQKGIQCFLVVVALLCVPWMLLFKPLVLRR
QYLRRKHLGTLNFGGIRVGNGPTEEDAEIIQHDQLSTHSEDADEFDFGDTMVHQAIHTIE
YCLGCISNTASYLRLWALSLAHAHVSEVLWTMVIHIGLSVKSLAGGLVLFFFFTAFATLT
VAILLIMEGLSAFLHALRLHWVEFQNKFYSGTGFKFLPFSFEHIREGKFEE
GenBank ID Protein 18653904
UniProtKB/Swiss-Prot ID Q53X12
UniProtKB/Swiss-Prot Entry Name Q53X12_HUMAN
PDB IDs Not Available
GenBank Gene ID L78933
GeneCard ID Not Available
GenAtlas ID Not Available
HGNC ID HGNC:865
References
General References Not Available