| Identification |
|---|
| HMDB Protein ID
| CDBP04572 |
| Secondary Accession Numbers
| Not Available |
| Name
| MAPK/MAK/MRK overlapping kinase |
| Description
| Not Available |
| Synonyms
|
- MOK protein kinase
- RAGE-1
- Renal tumor antigen 1
|
| Gene Name
| RAGE |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| Able to phosphorylate several exogenous substrates and to undergo autophosphorylation |
| GO Classification
|
| Function |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 14q32 |
| SNPs
| RAGE |
| Gene Sequence
|
>1260 bp
ATGAAGAACTATAAAGCAATTGGCAAAATAGGAGAGGGAACGTTTTCTGAAGTTATGAAG
ATGCAAAGCCTGAGAGATGGAAACTACTATGCATGTAAACAAATGAAGCAGCGCTTTGAA
AGTATTGAGCAAGTCAACAACCTACGAGAGATCCAAGCACTGAGGCGCCTGAATCCGCAC
CCAAACATTCTTATGTTGCATGAAGTGGTTTTTGACAGAAAATCTGGTTCTCTTGCACTA
ATATGTGAACTTATGGACATGAATATTTATGAGCTAATACGAGGGAGAAGATACCCATTA
TCAGAAAAAAAAATTATGCACTATATGTACCAGTTATGTAAGTCCCTGGATCATATTCAC
AGAAATGGAATATTTCACAGAGATGTAAAACCAGAAAATATACTAATAAAGCAGGATGTC
CTGAAATTAGGGGACTTTGGCTCCTGCCGGAGTGTCTATTCCAAGCAGCCGTACACGGAA
TACATCTCCACCCGCTGGTACCGGGCCCCGGAGTGTCTCCTCACTGATGGGTTCTACACG
TACAAGATGGACCTGTGGAGCGCCGGCTGTGTGTTCTACGAGATCGCCAGTCTGCAGCCC
CTCTTTCCTGGAGTAAATGAACTGGACCAAATCTCAAAAATCCACGATGTCATCGGCACA
CCCGCTCAGAAGATCCTCACCAAGTTCAAACAGTCGAGAGCTATGAATTTTGATTTTCCT
TTTAAAAAGGGATCAGGAATACCTCTACTAACAACCAATTTGTCCCCACAATGCCTCTCC
CTCCTGCACGCAATGGTGGCCTATGATCCCGATGAGAGAATCGCCGCCCACCAGGCCCTG
CAGCACCCCTACTTCCAAGAACAGAGGAAAACAGAGAAGCGGGCTCTGGGCAGCCACAGA
AAAGCTGGCTTTCCGGAGCACCCTGTGGCACCGGAACCACTCAGTAACAGCTGCCAGATT
TCCAAGGAGGGCAGAAAGCAGAAACAGTCCCTAAAGCAAGAGGAGGACCGTCCCAAGAGA
CGAGGACCGGCCTATGTCATGGAACTGCCCAAACTAAAGCTTTCGGGAGTGGTCAGACTG
TCGTCTTACTCCAGCCCCACGCTGCAGTCCGTGCTTGGATCTGGAACAAATGGAAGAGTG
CCGGTGCTGAGACCCTTGAAGTGCATCCCTGCGAGCAAGAAGACAGATCCGCAGAAGGAC
CTTAAGCCTGCCCCGCAGCAGTGTCGCCTGCCCACCATAGTGCGGAAAGGCGGAAGATAA
|
| Protein Properties |
|---|
| Number of Residues
| 419 |
| Molecular Weight
| 48013.4 |
| Theoretical pI
| 10.1 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>MAPK/MAK/MRK overlapping kinase
MKNYKAIGKIGEGTFSEVMKMQSLRDGNYYACKQMKQRFESIEQVNNLREIQALRRLNPH
PNILMLHEVVFDRKSGSLALICELMDMNIYELIRGRRYPLSEKKIMHYMYQLCKSLDHIH
RNGIFHRDVKPENILIKQDVLKLGDFGSCRSVYSKQPYTEYISTRWYRAPECLLTDGFYT
YKMDLWSAGCVFYEIASLQPLFPGVNELDQISKIHDVIGTPAQKILTKFKQSRAMNFDFP
FKKGSGIPLLTTNLSPQCLSLLHAMVAYDPDERIAAHQALQHPYFQEQRKTEKRALGSHR
KAGFPEHPVAPEPLSNSCQISKEGRKQKQSLKQEEDRPKRRGPAYVMELPKLKLSGVVRL
SSYSSPTLQSVLGSGTNGRVPVLRPLKCIPASKKTDPQKDLKPAPQQCRLPTIVRKGGR
|
| External Links |
|---|
| GenBank ID Protein
| 5139689 |
| UniProtKB/Swiss-Prot ID
| Q9UQ07 |
| UniProtKB/Swiss-Prot Entry Name
| MOK_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AB022694 |
| GeneCard ID
| RAGE |
| GenAtlas ID
| RAGE |
| HGNC ID
| HGNC:9833 |
| References |
|---|
| General References
| Not Available |