Identification |
HMDB Protein ID
| CDBP04570 |
Secondary Accession Numbers
| Not Available |
Name
| Cyclin-dependent kinase-like 3 |
Description
| Not Available |
Synonyms
|
- Serine/threonine-protein kinase NKIAMRE
|
Gene Name
| CDKL3 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in protein kinase activity |
Specific Function
| ATP + a protein = ADP + a phosphoprotein |
GO Classification
|
Function |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
nucleoside binding |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
protein kinase activity |
protein serine/threonine kinase activity |
binding |
Process |
phosphorylation |
phosphorus metabolic process |
phosphate metabolic process |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
|
Cellular Location
|
- Cytoplasm
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q31 |
SNPs
| CDKL3 |
Gene Sequence
|
>1779 bp
ATGGAGATGTATGAAACCCTTGGAAAAGTGGGAGAGGGAAGTTACGGAACAGTCATGAAA
TGTAAACATAAGAATACTGGGCAGATAGTGGCCATTAAGATATTTTATGAGAGACCAGAA
CAATCTGTCAACAAAATTGCGATGAGAGAAATAAAGTTTCTAAAGCAATTTCATCACGAA
AACCTGGTCAATCTGATTGAAGTTTTTAGACAGAAAAAGAAAATTCATTTGGTATTTGAA
TTTATTGACCACACAGTATTAGATGAGTTACAACATTATTGTCATGGACTAGAGAGTAAG
CGACTTAGAAAATACCTCTTCCAGATCCTTCGAGCAATTGACTATCTTCACAGTAATAAT
ATCATTCATCGAGATATAAAACCTGAGAATATTTTAGTATCCCAGTCAGGAATTACTAAG
CTCTGTGATTTTGGTTTTGCACGAACACTAGCAGCTCCTGGGGACATTTATACGGACTAT
GTGGCCACACGCTGGTATAGAGCTCCCGAATTAGTATTAAAAGATACTTCTTATGGAAAA
CCTGTGGATATCTGGGCTTTGGGCTGTATGATCATTGAGATGGCCACTGGAAATCCCTAT
CTTCCTAGTAGTTCTGATTTGGATTTACTCCATAAAATTGTTTTGAAAGTGGGCAATTTG
TCACCTCACTTGCAGAATATCTTTTCCAAGAGCCCCATTTTTGCTGGGGTAGTTCTTCCT
CAAGTTCAACACCCCAAAAATGCAAGAAAAAAATATCCAAAGCTTAATGGATTGTTGGCA
GATATAGTTCATGCTTGTTTACAAATTGATCCTGCTGACAGGATATCATCTAGTGATCTT
TTGCATCATGAGTATTTTACTAGAGATGGATTTATTGAAAAATTCATGCCAGAACTGAAA
GCTAAATTACTGCAGGAAGCAAAAGTCAATTCATTAATAAAGCCAAAAGAGAGTTCTAAA
GAAAATGAACTCAGGAAAGATGAAAGAAAAACAGTTTATACCAATACACTGCTAAGTAGT
TCAGTTTTGGGAAAGGAAATAGAAAAAGAGAAAAAGCCCAAGGAGATCAAAGTCAGAGTT
ATTAAAGTCAAAGGAGGAAGAGGAGATATCTCAGAACCAAAAAAGAAAGAGTATGAAGGT
GGACTTGGTCAACAGGATGCAAATGAAAATGTTCATCCTATGTCTCCAGATACAAAACTT
GTAACCATTGAACCACCAAACCCTATCAATCCCAGCACTAACTGTAATGGCTTGAAAGAA
AATCCACATTGCGGAGGTTCTGTGACAATGCCACCCATCAATCTAACTAACAGTAATTTG
ATGGCTGCAAATCTCAGTTCAAATCTCTTTCACCCCAGTGTGAGGTTAACTGAAAGAGCA
AAAAAGAGACGCACTTCTTCACAATCTATTGGACAAGTTATGCCTAATAGCAGGCAAGAG
GATCCAGGTCCTATTCAAAGCCAAATGGAGAAGGGTATATTTAATGAGCGAACAGGTCAC
AGTGACCAAATGGCAAATGAGAACAAAAGGAAGCTGAATTTTTCCAGATCTGACAGGAAA
GAATTCCATTTTCCAGAATTGCCTGTCACAATACAGTCAAAAGATACAAAAGGAATGGAA
GTTAAACAGATAAAAATGCTGAAGAGGGAGTCAAAGAAAACAGAGTCATCTAAGATACCA
ACTTTACTTAACGTGGATCAAAATCAAGAAAAACAAGAGGGTGGAGATGGCCATTGCGAG
GGGAAGAATTTGAAGAGAAACAGGTTTTTTTTCTGGTAG
|
Protein Properties |
Number of Residues
| 592 |
Molecular Weight
| 67513.3 |
Theoretical pI
| 9.88 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Cyclin-dependent kinase-like 3
MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLP
QVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELK
AKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRV
IKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
NPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQE
DPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGME
VKQIKMLKRESKKTESSKIPTLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW
|
External Links |
GenBank ID Protein
| 166064027 |
UniProtKB/Swiss-Prot ID
| Q8IVW4 |
UniProtKB/Swiss-Prot Entry Name
| CDKL3_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_001113575.1 |
GeneCard ID
| CDKL3 |
GenAtlas ID
| CDKL3 |
HGNC ID
| HGNC:15483 |
References |
General References
| Not Available |