Identification
HMDB Protein ID CDBP04570
Secondary Accession Numbers Not Available
Name Cyclin-dependent kinase-like 3
Description Not Available
Synonyms
  1. Serine/threonine-protein kinase NKIAMRE
Gene Name CDKL3
Protein Type Enzyme
Biological Properties
General Function Involved in protein kinase activity
Specific Function ATP + a protein = ADP + a phosphoprotein
GO Classification
Function
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
protein kinase activity
protein serine/threonine kinase activity
binding
Process
phosphorylation
phosphorus metabolic process
phosphate metabolic process
metabolic process
cellular metabolic process
protein amino acid phosphorylation
Cellular Location
  1. Cytoplasm
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q31
SNPs CDKL3
Gene Sequence
>1779 bp
ATGGAGATGTATGAAACCCTTGGAAAAGTGGGAGAGGGAAGTTACGGAACAGTCATGAAA
TGTAAACATAAGAATACTGGGCAGATAGTGGCCATTAAGATATTTTATGAGAGACCAGAA
CAATCTGTCAACAAAATTGCGATGAGAGAAATAAAGTTTCTAAAGCAATTTCATCACGAA
AACCTGGTCAATCTGATTGAAGTTTTTAGACAGAAAAAGAAAATTCATTTGGTATTTGAA
TTTATTGACCACACAGTATTAGATGAGTTACAACATTATTGTCATGGACTAGAGAGTAAG
CGACTTAGAAAATACCTCTTCCAGATCCTTCGAGCAATTGACTATCTTCACAGTAATAAT
ATCATTCATCGAGATATAAAACCTGAGAATATTTTAGTATCCCAGTCAGGAATTACTAAG
CTCTGTGATTTTGGTTTTGCACGAACACTAGCAGCTCCTGGGGACATTTATACGGACTAT
GTGGCCACACGCTGGTATAGAGCTCCCGAATTAGTATTAAAAGATACTTCTTATGGAAAA
CCTGTGGATATCTGGGCTTTGGGCTGTATGATCATTGAGATGGCCACTGGAAATCCCTAT
CTTCCTAGTAGTTCTGATTTGGATTTACTCCATAAAATTGTTTTGAAAGTGGGCAATTTG
TCACCTCACTTGCAGAATATCTTTTCCAAGAGCCCCATTTTTGCTGGGGTAGTTCTTCCT
CAAGTTCAACACCCCAAAAATGCAAGAAAAAAATATCCAAAGCTTAATGGATTGTTGGCA
GATATAGTTCATGCTTGTTTACAAATTGATCCTGCTGACAGGATATCATCTAGTGATCTT
TTGCATCATGAGTATTTTACTAGAGATGGATTTATTGAAAAATTCATGCCAGAACTGAAA
GCTAAATTACTGCAGGAAGCAAAAGTCAATTCATTAATAAAGCCAAAAGAGAGTTCTAAA
GAAAATGAACTCAGGAAAGATGAAAGAAAAACAGTTTATACCAATACACTGCTAAGTAGT
TCAGTTTTGGGAAAGGAAATAGAAAAAGAGAAAAAGCCCAAGGAGATCAAAGTCAGAGTT
ATTAAAGTCAAAGGAGGAAGAGGAGATATCTCAGAACCAAAAAAGAAAGAGTATGAAGGT
GGACTTGGTCAACAGGATGCAAATGAAAATGTTCATCCTATGTCTCCAGATACAAAACTT
GTAACCATTGAACCACCAAACCCTATCAATCCCAGCACTAACTGTAATGGCTTGAAAGAA
AATCCACATTGCGGAGGTTCTGTGACAATGCCACCCATCAATCTAACTAACAGTAATTTG
ATGGCTGCAAATCTCAGTTCAAATCTCTTTCACCCCAGTGTGAGGTTAACTGAAAGAGCA
AAAAAGAGACGCACTTCTTCACAATCTATTGGACAAGTTATGCCTAATAGCAGGCAAGAG
GATCCAGGTCCTATTCAAAGCCAAATGGAGAAGGGTATATTTAATGAGCGAACAGGTCAC
AGTGACCAAATGGCAAATGAGAACAAAAGGAAGCTGAATTTTTCCAGATCTGACAGGAAA
GAATTCCATTTTCCAGAATTGCCTGTCACAATACAGTCAAAAGATACAAAAGGAATGGAA
GTTAAACAGATAAAAATGCTGAAGAGGGAGTCAAAGAAAACAGAGTCATCTAAGATACCA
ACTTTACTTAACGTGGATCAAAATCAAGAAAAACAAGAGGGTGGAGATGGCCATTGCGAG
GGGAAGAATTTGAAGAGAAACAGGTTTTTTTTCTGGTAG
Protein Properties
Number of Residues 592
Molecular Weight 67513.3
Theoretical pI 9.88
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Cyclin-dependent kinase-like 3
MEMYETLGKVGEGSYGTVMKCKHKNTGQIVAIKIFYERPEQSVNKIAMREIKFLKQFHHE
NLVNLIEVFRQKKKIHLVFEFIDHTVLDELQHYCHGLESKRLRKYLFQILRAIDYLHSNN
IIHRDIKPENILVSQSGITKLCDFGFARTLAAPGDIYTDYVATRWYRAPELVLKDTSYGK
PVDIWALGCMIIEMATGNPYLPSSSDLDLLHKIVLKVGNLSPHLQNIFSKSPIFAGVVLP
QVQHPKNARKKYPKLNGLLADIVHACLQIDPADRISSSDLLHHEYFTRDGFIEKFMPELK
AKLLQEAKVNSLIKPKESSKENELRKDERKTVYTNTLLSSSVLGKEIEKEKKPKEIKVRV
IKVKGGRGDISEPKKKEYEGGLGQQDANENVHPMSPDTKLVTIEPPNPINPSTNCNGLKE
NPHCGGSVTMPPINLTNSNLMAANLSSNLFHPSVRLTERAKKRRTSSQSIGQVMPNSRQE
DPGPIQSQMEKGIFNERTGHSDQMANENKRKLNFSRSDRKEFHFPELPVTIQSKDTKGME
VKQIKMLKRESKKTESSKIPTLLNVDQNQEKQEGGDGHCEGKNLKRNRFFFW
GenBank ID Protein 166064027
UniProtKB/Swiss-Prot ID Q8IVW4
UniProtKB/Swiss-Prot Entry Name CDKL3_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001113575.1
GeneCard ID CDKL3
GenAtlas ID CDKL3
HGNC ID HGNC:15483
References
General References Not Available