Cannabis Compound Database: Showing Protein Serine/threonine-protein kinase N3 (CDBP04565)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP04565

Secondary Accession Numbers

Not Available

Name

Serine/threonine-protein kinase N3

Description

Not Available

Synonyms

Protein kinase PKN-beta
Protein-kinase C-related kinase 3

Gene Name

PKN3

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein serine/threonine kinase activity

Specific Function

Contributes to invasiveness in malignant prostate cancer

GO Classification

Component
cell part
intracellular
Function
atp binding
protein kinase activity
protein serine/threonine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
Process
phosphorus metabolic process
phosphate metabolic process
metabolic process
biological regulation
regulation of biological process
cellular metabolic process
regulation of cellular process
signal transduction
protein amino acid phosphorylation
phosphorylation

Cellular Location

Nucleus
Cytoplasm
perinuclear region

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:9

Locus

9q34.11

SNPs

PKN3

Gene Sequence

>2670 bp
ATGGAGGAGGGGGCGCCGCGGCAGCCTGGGCCGAGCCAGTGGCCCCCAGAGGATGAGAAG
GAGGTGATCCGCCGGGCCATCCAGAAAGAGCTGAAGATCAAGGAGGGGGTGGAGAACCTG
CGGCGCGTGGCCACAGACCGCCGCCACTTGGGCCATGTGCAGCAGCTGCTGCGGTCCTCC
AACCGCCGCCTGGAGCAGCTGCATGGCGAGCTGCGGGAGCTGCACGCCCGAATCCTGCTG
CCCGGCCCTGGGCCTGGCCCAGCTGAGCCTGTGGCCTCAGGACCCCGGCCGTGGGCAGAG
CAGCTCAGGGCTCGGCACCTAGAGGCTCTCCGGAGGCAGCTGCATGTGGAGCTGAAGGTG
AAACAGGGGGCTGAGAACATGACCCACACGTGCGCCAGTGGCACCCCCAAGGAGAGGAAG
CTCCTTGCAGCTGCCCAGCAGATGCTGCGGGACAGCCAGCTGAAGGTGGCCCTGCTGCGG
ATGAAGATCAGCAGCCTGGAGGCCAGTGGGTCCCCGGAGCCAGGGCCTGAGCTACTGGCG
GAGGAGCTACAGCATCGACTGCACGTTGAGGCAGCGGTGGCTGAGGGCGCCAAGAACGTG
GTGAAACTGCTTAGTAGCCGGAGAACACAGGACCGCAAGGCACTGGCTGAGGCCCAGGCC
CAGCTACAGGAGTCCTCTCAGAAACTGGACCTCCTGCGCCTGGCCTTGGAGCAGCTGCTG
GAGCAACTGCCTCCTGCCCACCCTTTGCGCAGCAGAGTGACCCGAGAGTTGCGGGCTGCG
GTGCCTGGATACCCCCAGCCTTCAGGGACACCTGTGAAGCCCACCGCCCTAACAGGGACA
CTGCAGGTCCGCCTCCTGGGCTGTGAACAGTTGCTGACAGCCGTGCCTGGGCGCTCCCCA
GCGGCCGCACTGGCCAGCAGCCCCTCCGAGGGCTGGCTTCGGACCAAGGCCAAGCACCAG
CGTGGCCGAGGCGAGCTTGCCAGTGAGGTGCTGGCTGTGCTAAAGGTGGACAACCGTGTT
GTGGGGCAGACGGGCTGGGGGCAGGTGGCCGAACAGTCCTGGGACCAGACCTTTGTCATC
CCACTGGAGCGAGCCCGTGAGCTGGAGATTGGGGTACACTGGCGGGACTGGCGGCAGCTA
TGTGGCGTGGCCTTCCTGAGACTTGAAGACTTCCTGGACAATGCCTGTCACCAACTGTCC
CTCAGCCTGGTACCGCAGGGACTGCTTTTTGCCCAGGTGACCTTCTGCGATCCTGTCATT
GAGAGGCGGCCCCGGCTGCAGAGGCAGGAACGCATCTTCTCTAAACGCAGAGGCCAGGAC
TTCCTGAGGCGTTCGCAGATGAACCTCGGCATGGCGGCCTGGGGGCGCCTCGTCATGAAC
CTGCTGCCCCCCTGCAGCTCCCCGAGCACAATCAGCCCCCCTAAAGGATGCCCTCGGACC
CCAACAACACTGCGAGAGGCCTCTGACCCTGCCACTCCCAGTAATTTCCTGCCCAAGAAG
ACCCCCTTGGGTGAAGAGATGACACCCCCACCCAAGCCCCCACGCCTCTACCTCCCCCAG
GAGCCAACATCCGAGGAGACTCCGCGCACCAAACGTCCCCATATGGAGCCTAGGACTCGA
CGTGGGCCATCTCCACCAGCCTCCCCCACCAGGAAACCCCCTCGGCTTCAGGACTTCCGC
TGCTTAGCTGTGCTGGGCCGGGGACACTTTGGGAAGGTCCTCCTGGTCCAGTTCAAGGGG
ACAGGGAAATACTACGCCATCAAAGCACTGAAGAAGCAGGAGGTGCTCAGCCGGGACGAG
ATAGAGAGCCTGTACTGCGAGAAGCGGATCCTGGAGGCTGTGGGCTGCACAGGGCACCCT
TTCCTGCTCTCCCTCCTTGTCTGCTTCCAGACCTCCAGCCATGCCCGCTTTGTGACTGAG
TTTGTGCCTGGTGGTGACCTCATGATGCAGATCCACGAGGATGTCTTCCCCGAGCCCCAG
GCCCGCTTCTACGTGGCTTGTGTTGTCCTGGGGCTGCAGTTCTTACACGAGAAGAAGATC
ATTTACAGGGACCTGAAGTTGGATAACCTTCTGCTGGATGCCCAGGGATTCCTGAAGATC
GCAGACTTTGGACTCTGCAAGGAAGGGATCGGCTTCGGGGACCGGACTAGCACCTTCTGT
GGCACCCCGGAGTTCCTGGCTCCCGAGGTGCTGACCCAGGAGGCATACACACAGGCCGTC
GACTGGTGGGCGCTGGGTGTGCTGCTCTACGAGATGCTGGTGGGTGAGTGCCCGTTCCCA
GGGGACACAGAGGAAGAGGTGTTTGACTGCATCGTCAACATGGACGCCCCCTACCCCGGC
TTTCTGTCGGTGCAAGGGCTTGAGTTCATTCAGAAGCTCCTCCAGAAGTGCCCGGAGAAG
CGCCTCGGGGCAGGTGAGCAGGATGCCGAGGAGATCAAGGTCCAGCCATTCTTCAGGACC
ACCAACTGGCAAGCCCTGCTCGCCCGCACCATCCAGCCCCCCTTCGTGCCTACCCTGTGT
GGCCCTGCGGACCTGCGCTACTTTGAGGGCGAGTTCACAGGGCTGCCGCCTGCCCTGACC
CCACCTGCACCCCACAGCCTCCTCACTGCCCGCCAACAGGCCGCCTTCCGGGACTTCGAC
TTTGTGTCAGAGCGATTCCTGGAACCCTGA

Protein Properties

Number of Residues

889

Molecular Weight

99419.8

Theoretical pI

8.56

Pfam Domain Function

Pkinase (PF00069 )
Pkinase_C (PF00433 )
HR1 (PF02185 )

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Serine/threonine-protein kinase N3
MEEGAPRQPGPSQWPPEDEKEVIRRAIQKELKIKEGVENLRRVATDRRHLGHVQQLLRSS
NRRLEQLHGELRELHARILLPGPGPGPAEPVASGPRPWAEQLRARHLEALRRQLHVELKV
KQGAENMTHTCASGTPKERKLLAAAQQMLRDSQLKVALLRMKISSLEASGSPEPGPELLA
EELQHRLHVEAAVAEGAKNVVKLLSSRRTQDRKALAEAQAQLQESSQKLDLLRLALEQLL
EQLPPAHPLRSRVTRELRAAVPGYPQPSGTPVKPTALTGTLQVRLLGCEQLLTAVPGRSP
AAALASSPSEGWLRTKAKHQRGRGELASEVLAVLKVDNRVVGQTGWGQVAEQSWDQTFVI
PLERARELEIGVHWRDWRQLCGVAFLRLEDFLDNACHQLSLSLVPQGLLFAQVTFCDPVI
ERRPRLQRQERIFSKRRGQDFLRASQMNLGMAAWGRLVMNLLPPCSSPSTISPPKGCPRT
PTTLREASDPATPSNFLPKKTPLGEEMTPPPKPPRLYLPQEPTSEETPRTKRPHMEPRTR
RGPSPPASPTRKPPRLQDFRCLAVLGRGHFGKVLLVQFKGTGKYYAIKALKKQEVLSRDE
IESLYCEKRILEAVGCTGHPFLLSLLACFQTSSHACFVTEFVPGGDLMMQIHEDVFPEPQ
ARFYVACVVLGLQFLHEKKIIYRDLKLDNLLLDAQGFLKIADFGLCKEGIGFGDRTSTFC
GTPEFLAPEVLTQEAYTRAVDWWGLGVLLYEMLVGECPFPGDTEEEVFDCIVNMDAPYPG
FLSVQGLEFIQKLLQKCPEKRLGAGEQDAEEIKVQPFFRTTNWQALLARTIQPPFVPTLC
GPADLRYFEGEFTGLPPALTPPAPHSLLTARQQAAFRDFDFVSERFLEP

External Links

GenBank ID Protein

6088096

UniProtKB/Swiss-Prot ID

Q6P5Z2

UniProtKB/Swiss-Prot Entry Name

PKN3_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AB019692

GeneCard ID