Identification |
HMDB Protein ID
| CDBP04557 |
Secondary Accession Numbers
| Not Available |
Name
| U4/U6 small nuclear ribonucleoprotein Prp4 |
Description
| Not Available |
Synonyms
|
- PRP4 homolog
- U4/U6 snRNP 60 kDa protein
- WD splicing factor Prp4
- hPrp4
|
Gene Name
| PRPF4 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in RNA splicing |
Specific Function
| Involved in pre-mRNA splicing |
GO Classification
|
Process |
rna metabolic process |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
rna processing |
rna splicing |
|
Cellular Location
|
- Nucleus speckle
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:9 |
Locus
| 9q31-q33 |
SNPs
| PRPF4 |
Gene Sequence
|
>1569 bp
ATGGCTTCCTCGCGAGCCTCTTCCACGCAGGCAACCAAAACTAAAGCACCCGACGACTTA
GTTGCTCCGGTCGTGAAGAAACCACACATCTATTATGGAAGTTTGGAAGAGAAGGAGAGG
GAGCGTCTGGCCAAAGGAGAGTCTGGGATTTTGGGGAAAGACGGACTTAAAGCAGGGATC
GAAGCTGGAAATATTAATATAACCTCTGGAGAAGTGTTTGAAATTGAAGAGCATATCAGC
GAGCGACAGGCAGAAGTATTGGCTGAGTTTGAGAGAAGGAAGCGAGCCCGGCAGATCAAT
GTTTCCACAGATGACTCAGAGGTCAAAGCTTGCCTTAGAGCCTTGGGGGAACCCATCACA
CTTTTTGGAGAGGGTCCTGCTGAAAGAAGAGAAAGGTTAAGAAATATCCTCTCAGTTGTC
GGTACTGATGCCTTGAAAAAGACCAAAAAGGATGATGAGAAGTCTAAAAAGTCCAAAGAA
GAGTATCAGCAAACCTGGTATCATGAAGGACCAAATAGCTTGAAGGTGGCAAGACTATGG
ATTGCTAATTATTCGTTGCCCAGGGCAATGAAACGCTTGGAAGAGGCCCGACTCCATAAG
GAGATTCCTGAGACAACAAGGACCTCCCAGATGCAAGAGCTGCACAAGTCTCTCCGGTCT
TTGAATAATTTTTGCAGTCAGATTGGGGATGATCGGCCTATCTCCTACTGTCACTTTAGT
CCCAATTCCAAGATGCTGGCCACAGCTTGTTGGAGTGGGCTTTGCAAGCTCTGGTCTGTT
CCTGATTGCAACCTCCTTCACACTCTTCGAGGGCATAACACAAATGTAGGAGCAATTGTA
TTCCATCCCAAATCCACTGTCTCCTTGGACCCAAAAGATGTCAACCTGGCCTCTTGTGCG
GCTGATGGCTCTGTGAAGCTTTGGAGTCTCGACAGTGATGAACCAGTGGCAGATATTGAA
GGCCATACAGTGCGTGTGGCGCGGGTAATGTGGCATCCTTCAGGACGTTTCCTGGGCACC
ACCTGCTATGACCGTTCATGGCGCTTATGGGATTTGGAGGCTCAAGAGGAGATCCTGCAT
CAGGAAGGCCATAGCATGGGTGTGTATGACATTGCCTTCCATCAAGATGGCTCTTTGGCT
GGCACTGGGGGACTGGATGCATTTGGTCGAGTTTGGGACCTACGCACAGGACGTTGTATC
ATGTTCTTAGAAGGCCACCTGAAAGAAATCTATGGAATAAATTTCTCCCCCAATGGCTAT
CACATTGCAACCGGCAGTGGTGACAACACCTGCAAAGTGTGGGACCTCCGACAGCGGCGT
TGCGTCTACACCATCCCTGCTCATCAGAACTTAGTGACTGGTGTCAAGTTTGAGCCTATC
CATGGGAACTTCTTGCTTACTGGTGCCTATGATAACACAGCCAAGATCTGGACGCACCCA
GGCTGGTCCCCGCTGAAGACTCTGGCTGGCCACGAAGGCAAAGTGATGGGCCTAGATATT
TCTTCCGATGGGCAGCTCATAGCCACTTGCTCATATGACAGGACCTTCAAGCTGTGGATG
GCTGAATAG
|
Protein Properties |
Number of Residues
| 522 |
Molecular Weight
| 58448.7 |
Theoretical pI
| 7.44 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>U4/U6 small nuclear ribonucleoprotein Prp4
MASSRASSTQATKTKAPDDLVAPVVKKPHIYYGSLEEKERERLAKGESGILGKDGLKAGI
EAGNINITSGEVFEIEEHISERQAEVLAEFERRKRARQINVSTDDSEVKACLRALGEPIT
LFGEGPAERRERLRNILSVVGTDALKKTKKDDEKSKKSKEEYQQTWYHEGPNSLKVARLW
IANYSLPRAMKRLEEARLHKEIPETTRTSQMQELHKSLRSLNNFCSQIGDDRPISYCHFS
PNSKMLATACWSGLCKLWSVPDCNLLHTLRGHNTNVGAIVFHPKSTVSLDPKDVNLASCA
ADGSVKLWSLDSDEPVADIEGHTVRVARVMWHPSGRFLGTTCYDRSWRLWDLEAQEEILH
QEGHSMGVYDIAFHQDGSLAGTGGLDAFGRVWDLRTGRCIMFLEGHLKEIYGINFSPNGY
HIATGSGDNTCKVWDLRQRRCVYTIPAHQNLVTGVKFEPIHGNFLLTGAYDNTAKIWTHP
GWSPLKTLAGHEGKVMGLDISSDGQLIATCSYDRTFKLWMAE
|
External Links |
GenBank ID Protein
| 24431950 |
UniProtKB/Swiss-Prot ID
| O43172 |
UniProtKB/Swiss-Prot Entry Name
| PRP4_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_004697.3 |
GeneCard ID
| PRPF4 |
GenAtlas ID
| PRPF4 |
HGNC ID
| HGNC:17349 |
References |
General References
| Not Available |