| Identification |
|---|
| HMDB Protein ID
| CDBP04537 |
| Secondary Accession Numbers
| Not Available |
| Name
| Serine/threonine-protein kinase SBK1 |
| Description
| Not Available |
| Synonyms
|
- SH3-binding kinase 1
|
| Gene Name
| SBK1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein kinase activity |
| Specific Function
| May be involved in signal-transduction pathways related to the control of brain development |
| GO Classification
|
| Function |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein binding |
| protein kinase activity |
| protein serine/threonine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16p11.2 |
| SNPs
| SBK1 |
| Gene Sequence
|
>1275 bp
ATGAGCGTGGGCTGCCCAGAGCCTGAGCCGCCCCGCTCCCTGACCTGCTGTGGGCCGGGG
ACTGCCCCTGGGCCTGGTGCCGGTGTGCCCCTTCTCACTGAAGACATGCAGGCCCTGACT
CTCCGCACACTGGCCGCCAGCGACGTCACCAAGCACTACGAACTAGTCCGGGAGCTGGGC
AAAGGCACCTATGGGAAGGTTGACCTGGTGGTCTACAAGGGCACAGGCACAAAAATGGCA
CTGAAGTTTGTGAACAAGAGCAAAACCAAGCTGAAGAACTTCCTACGGGAGGTGAGCATC
ACCAACAGCCTCTCCTCCAGCCCCTTCATCATCAAGGTCTTTGACGTGGTCTTTGAGACA
GAGGACTGCTACGTCTTTGCCCAGGAGTACGCACCTGCTGGGGACCTGTTTGACATCATC
CCTCCCCAGGTGGGGCTCCCTGAGGACACGGTGAAGCGCTGTGTGCAGCAGCTGGGCCTG
GCGCTGGACTTCATGCACGGGCGGCAGCTGGTGCACCGCGACATCAAGCCCGAGAACGTG
CTGCTGTTCGACCGCGAGTGCCGCCGCGTAAAGCTGGCCGACTTCGGCATGACGCGCCGC
GTGGGCTGCCGCGTCAAGCGCGTGAGCGGCACCATCCCTTACACGGCGCCTGAGGTGTGC
CAGGCGGGCCGCGCCGACGGGCTGGCGGTGGACACGGGCGTGGACGTGTGGGCCTTCGGC
GTGCTCATCTTCTGCGTGCTCACCGGCAACTTCCCGTGGGAGGCGGCGTCGGGCGCCGAC
GCCTTCTTCGAGGAGTTCGTGCGCTGGCAGCGGGGCCGCCTGCCGGGGCTGCCTTCGCAG
TGGCGCCGCTTCACCGAGCCCGCGCTGCGCATGTTCCAGCGCTTACTGGCCCTGGAGCCC
GAGCGCCGCGGCCCAGCCAAGGAGGTGTTCCGCTTCCTCAAGCACGAGCTCACGTCCGAG
CTGCGCCGCCGGCCCTCGCACCGCGCGCGCAAGCCCCCCGGGGACCGCCCGCCCGCCGCC
GGGCCACTGCGCCTCGAGGCGCCTGGGCCGCTCAAGCGGACGGTGCTGACCGAGAGCGGC
AGCGGCTCCCGGCCCGCGCCCCCCGCCGTCGGGTCGGTGCCCTTGCCCGTGCCGGTGCCG
GTGCCAGTGCCCGTGCCGGTGCCTGTGCCCGAGCCCGGCCTAGCTCCCCAGGGGCCCCCC
GGCCGGACCGACGGCCGCGCGGACAAGAGCAAAGGGCAGGTGGTGCTGGCCACGGCCATC
GAGATCTGCGTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 424 |
| Molecular Weight
| 46251.3 |
| Theoretical pI
| 9.47 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Serine/threonine-protein kinase SBK1
MSVGCPEPEPPRSLTCCGPGTAPGPGAGVPLLTEDMQALTLRTLAASDVTKHYELVRELG
KGTYGKVDLVVYKGTGTKMALKFVNKSKTKLKNFLREVSITNSLSSSPFIIKVFDVVFET
EDCYVFAQEYAPAGDLFDIIPPQVGLPEDTVKRCVQQLGLALDFMHGRQLVHRDIKPENV
LLFDRECRRVKLADFGMTRRVGCRVKRVSGTIPYTAPEVCQAGRADGLAVDTGVDVWAFG
VLIFCVLTGNFPWEAASGADAFFEEFVRWQRGRLPGLPSQWRRFTEPALRMFQRLLALEP
ERRGPAKEVFRFLKHELTSELRRRPSHRARKPPGDRPPAAGPLRLEAPGPLKRTVLTESG
SGSRPAPPAVGSVPLPVPVPVPVPVPVPVPEPGLAPQGPPGRTDGRADKSKGQVVLATAI
EICV
|
| External Links |
|---|
| GenBank ID Protein
| 62005104 |
| UniProtKB/Swiss-Prot ID
| Q52WX2 |
| UniProtKB/Swiss-Prot Entry Name
| SBK1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AY874862 |
| GeneCard ID
| SBK1 |
| GenAtlas ID
| SBK1 |
| HGNC ID
| HGNC:17699 |
| References |
|---|
| General References
| Not Available |