| Identification |
|---|
| HMDB Protein ID
| CDBP04519 |
| Secondary Accession Numbers
| Not Available |
| Name
| Myosin-IIIb |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| MYO3B |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in motor activity |
| Specific Function
| Probable actin-based motor with a protein kinase activity |
| GO Classification
|
| Component |
| myosin complex |
| macromolecular complex |
| protein complex |
| Function |
| hydrolase activity |
| transferase activity |
| motor activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein kinase activity |
| nucleoside-triphosphatase activity |
| protein serine/threonine kinase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| binding |
| pyrophosphatase activity |
| catalytic activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| phosphorylation |
|
| Cellular Location
|
- Cytoplasm
- cytoskeleton
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:2 |
| Locus
| 2q31.1-q31.2 |
| SNPs
| MYO3B |
| Gene Sequence
|
>4026 bp
ATGAAACATCTGTATGGATTATTTCACTATAATCCTATGATGCTTGGACTTGAATCACTT
CCAGATCCCACAGACACCTGGGAAATTATAGAGACCATTGGTAAAGGCACCTATGGCAAA
GTCTACAAGGTAACTAACAAGAGAGATGGGAGCCTGGCTGCAGTGAAAATTCTGGATCCA
GTCAGTGATATGGATGAAGAAATTGAGGCAGAATACAACATTTTGCAGTTCCTTCCTAAT
CATCCCAATGTTGTAAAGTTTTATGGGATGTTTTACAAAGCGGATCACTGTGTAGGGGGA
CAGCTGTGGCTGGTCCTGGAGCTGTGTAATGGGGGCTCAGTCACTGAGCTTGTCAAAGGT
CTACTCAGATGTGGCCAGCGGTTGGATGAAGCAATGATCTCATACATCTTGTACGGGGCC
CTCTTGGGCCTTCAGCATTTGCACAACAACCGAATCATCCACCGTGATGTGAAGGGGAAT
AACATTCTTCTGACAACAGAAGGAGGAGTTAAGCTCGTTGACTTTGGTGTTTCAGCTCAA
CTCACCAGTACACGTCTGCGGAGAAACACATCTGTTGGCACCCCGTTCTGGATGGCCCCT
GAGGTCATTGCCTGTGAGCAGCAGTATGACTCTTCCTATGACGCTCGCTGTGACGTCTGG
TCCTTGGGGATCACAGCTATTGAACTGGGGGATGGAGACCCTCCCCTCTTTGACATGCAT
CCTGTGAAAACACTCTTTAAGATTCCAAGAAATCCTCCACCTACTTTACTTCATCCAGAA
AAATGGTGTGAAGAATTCAACCACTTTATTTCACAGTGTCTTATTAAGGATTTTGAAAGG
CGACCTTCCGTCACACATCTCCTTGACCACCCATTTATTAAAGGAGTACATGGAAAAGTT
CTGTTTCTGCAAAAACAGCTGGCCAAGGTTCTCCAAGACCAGAAGCATCAAAATCCTGTT
GCTAAAACCAGGCATGAGAGGATGCATACCAGAAGACCTTATCATGTGGAAGATGCTGAA
AAATACTGCCTTGAGGATGATTTGGTCAACCTAGAGGTTCTGGATGAGGATACAATTATC
CATCAGTTGCAGAAACGTTATGCAGACTTGCTAATTTACACATATGTTGGAGACATCTTA
ATTGCCTTAAACCCCTTCCAGAATCTAAGCATATACTCTCCACAGTTTTCCAGACTTTAT
CATGGGGTGAAACGCGCCTCCAATCCCCCCCACATATTTGCATCAGCAGATGCTGCTTAC
CAGTGCATGGTTACTCTCAGCAAAGACCAGTGCATTGTCATCAGCGGAGAGAGTGGCTCT
GGGAAGACAGAAAGCGCCCACCTGATTGTTCAGCATTTGACTTTCTTGGGAAAGGCCAAT
AATCAGACCTTGAGAGAGAAAATTCTACAAGTCAACTCCCTGGTGGAAGCCTTTGGGAAC
TCATGCACTGCCATCAATGACAACTCGAGCCGTTTTGGAAAATATCTGGAAATGATGTTT
ACACCAACTGGAGTTGTGATGGGGGCAAGAATCTCTGAATATCTCCTGGAAAAATCCAGA
GTTATAAAACAGGCAGCGAGAGAGAAAAATTTTCATATATTTTACTATATTTATGCTGGT
CTTCATCACCAAAAGAAGCTTTCTGATTTCAGACTTCCTGAGGAAAAACCTCCTAGGTAC
ATAGCTGATGAAACTGGAAGGGTGATGCACGACATAACTTCCAAGGAGTCTTACAGAAGA
CAATTCGAAGCAATTCAGCATTGCTTCAGGATTATAGGGTTCACGGACAAAGAGGTGCAC
TCAGTGTACAGAATTTTGGCTGGGATTTTGAATATTGGGAACATTGAGTTCGCAGCTATT
TCCTCTCAACATCAGACTGATAAAAGTGAGGTGCCCAATGCTGAAGCTTTGCAAAATGCT
GCCTCTGTTCTGTGCATTAGCCCTGAAGAGCTCCAGGAGGCCCTCACCTCCCACTGTGTG
GTCACCCGGGGCGAGACCATCATCCGTGCCAACACTGTAGACAGGGCTGCGGACGTTCGA
GACGCCATGTCCAAAGCCCTGTATGGGAGGCTCTTCAGCTGGATTGTGAATCGCATTAAT
ACACTCCTGCAGCCAGACGAAAACATATGTAGTGCAGGAGGTGGAATGAATGTGGGGATC
TTGGATATCTTTGGATTCGAGAATTTTCAGAGAAATTCATTTGAGCAGCTCTGCATAAAC
ATCGCCAATGAGCAAATCCAGTACTATTTCAATCAGCATGTTTTTGCTCTTGAGCAGATG
GAATATCAGAATGAAGGCATTGATGCTGTACCCGTGGAATATGAGGACAACCGCCCGCTC
TTGGACATGTTCCTCCAGAAACCCCTGGGACTGCTTGCACTTTTGGATGAGGAAAGTCGG
TTTCCCCAAGCAACTGACCAGACCCTGGTTGATAAATTTGAAGATAATCTACGATGCAAA
TACTTCTGGAGGCCCAAAGGAGTGGAACTGTGCTTTGGCATTCAGCATTATGCTGGAAAG
GTATTATATGATGCTTCTGGGGTTCTTGAGAAAAATAGAGACACTCTCCCTGCCGATGTG
GTTGTGGTCCTGAGAACGTCAGAAAACAAGCTTCTTCAGCAGCTCTTCTCAATCCCTCTG
ACCAAAACAGGTAATTTGGCCCAGACAAGAGCTAGGATAACAGTGGCCTCAAGTTCTTTG
CCTCCACATTTCAGTGCTGGGAAAGCCAAGGTGGACACTCTGGAGGTGATACGGCATCCG
GAAGAAACCACCAACATGAAGAGGCAAACTGTGGCTTCTTACTTCCGGTATTCTCTGATG
GACCTGCTCTCCAAAATGGTGGTTGGACAGCCCCACTTTGTGCGCTGCATTAAACCCAAT
GATGACCGAGAGGCCCTGCAGTTCTCTCGAGAGAGGGTGCTGGCCCAGCTCCGCTCCACA
GGGATTCTGGAGACAGTCAGCATCCGCCGCCAGGGCTATTCCCACCGCATCCTTTTTGAA
GAATTTGTGAAAAGGTATTATTACTTGGCATTCACAGCACATCAAACACCTCTTGCTAGC
AAAGAGAGCTGTGTGGCTATCTTGGAAAAGTCCAGATTAGATCACTGGGTACTGGGAAAA
ACAAAGGTTTTTCTCAAATATTACCATGTTGAGCAATTAAATTTGCTGCTTCGAGAAGTC
ATAGGCAGAGTGGTTGTGCTGCAGGCATATACCAAGGGGTGGCTTGGAGCCAGGAGATAC
AAAAGGGTCAGAGAGAAGAGAGAGAAGGGAGCCATTGCCATCCAGTCAGCCTGGAGAGGA
TATGATGCTCGGAGGAAATTTAAGAAAATAAGCAACAGAAGGAATGAGTCTGCTGCTCAT
AATCAAGCAGGGGACACTTCAAACCAAAGCAGTGGGCCACATTCCCCCGTCGCAGCAGGT
ACGAGGGGAAGTGCCGAGGTTCAAGACTGCAGCGAGCCTGGTGACCATAAAGTTCTCAGG
GGCTCTGTACATCGTAGGAGCCATTCACAAGCAGAATCCAACAATGGCCGTACACAGACT
TCAAGCAACTCTCCTGCTGTCACAGAGAAAAATGGGCATTCACAAGCCCAGAGTTCTCCA
AAAGGGTGCGATATCTTCGCAGGACATGCAAACAAGCACTCGGTTTCTGGGACTGATTTG
CTGTCTTCTCGGATATGCCATCCTGCTCCAGATCAGCAAGGATTGAGTCTCTGGGGAGCC
CCTCAAAAGCCTGGTTCAGAAAATGGTCTTGCACAGAAGCATCGAACACCTCGCCGACGA
TGTCAGCAGCCCAAAATGCTGAGTAGCCCTGAGGACACCATGTACTATAACCAGTTAAAT
GGAACTCTAGAATATCAAGGGAGCAAGAGGAAGCCAAGAAAACTTGGCCAAATCAAAGTA
CTTGATGGGGAAGATGAATATTACAAATCTCTGTCACCAGTGGACTGTATCCCTGAGGAG
AACAACTCAGCCCACCCTTCCTTTTTTTCTTCATCCTCAAAAGGAGACTCTTTTGCTCAA
CATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 1341 |
| Molecular Weight
| 151827.5 |
| Theoretical pI
| 8.23 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Myosin-IIIb
MKHLYGLFHYNPMMLGLESLPDPTDTWEIIETIGKGTYGKVYKVTNKRDGSLAAVKILDP
VSDMDEEIEAEYNILQFLPNHPNVVKFYGMFYKADHCVGGQLWLVLELCNGGSVTELVKG
LLRCGQRLDEAMISYILYGALLGLQHLHNNRIIHRDVKGNNILLTTEGGVKLVDFGVSAQ
LTSTRLRRNTSVGTPFWMAPEVIACEQQYDSSYDARCDVWSLGITAIELGDGDPPLFDMH
PVKTLFKIPRNPPPTLLHPEKWCEEFNHFISQCLIKDFERRPSVTHLLDHPFIKGVHGKV
LFLQKQLAKVLQDQKHQNPVAKTRHERMHTRRPYHVEDAEKYCLEDDLVNLEVLDEDTII
HQLQKRYADLLIYTYVGDILIALNPFQNLSIYSPQFSRLYHGVKRASNPPHIFASADAAY
QCMVTLSKDQCIVISGESGSGKTESAHLIVQHLTFLGKANNQTLREKILQVNSLVEAFGN
SCTAINDNSSRFGKYLEMMFTPTGVVMGARISEYLLEKSRVIKQAAREKNFHIFYYIYAG
LHHQKKLSDFRLPEEKPPRYIADETGRVMHDITSKESYRRQFEAIQHCFRIIGFTDKEVH
SVYRILAGILNIGNIEFAAISSQHQTDKSEVPNAEALQNAASVLCISPEELQEALTSHCV
VTRGETIIRANTVDRAADVRDAMSKALYGRLFSWIVNRINTLLQPDENICSAGGGMNVGI
LDIFGFENFQRNSFEQLCINIANEQIQYYFNQHVFALEQMEYQNEGIDAVPVEYEDNRPL
LDMFLQKPLGLLALLDEESRFPQATDQTLVDKFEDNLRCKYFWRPKGVELCFGIQHYAGK
VLYDASGVLEKNRDTLPADVVVVLRTSENKLLQQLFSIPLTKTGNLAQTRARITVASSSL
PPHFSAGKAKVDTLEVIRHPEETTNMKRQTVASYFRYSLMDLLSKMVVGQPHFVRCIKPN
DDREALQFSRERVLAQLRSTGILETVSIRRQGYSHRILFEEFVKRYYYLAFTAHQTPLAS
KESCVAILEKSRLDHWVLGKTKVFLKYYHVEQLNLLLREVIGRVVVLQAYTKGWLGARRY
KRVREKREKGAIAIQSAWRGYDARRKFKKISNRRNESAAHNQAGDTSNQSSGPHSPVAAG
TRGSAEVQDCSEPGDHKVLRGSVHRRSHSQAESNNGRTQTSSNSPAVTEKNGHSQAQSSP
KGCDIFAGHANKHSVSGTDLLSSRICHPAPDQQGLSLWGAPQKPGSENGLAQKHRTPRRR
CQQPKMLSSPEDTMYYNQLNGTLEYQGSKRKPRKLGQIKVLDGEDEYYKSLSPVDCIPEE
NNSAHPSFFSSSSKGDSFAQH
|
| External Links |
|---|
| GenBank ID Protein
| 284172512 |
| UniProtKB/Swiss-Prot ID
| Q8WXR4 |
| UniProtKB/Swiss-Prot Entry Name
| MYO3B_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_138995.3 |
| GeneCard ID
| MYO3B |
| GenAtlas ID
| MYO3B |
| HGNC ID
| HGNC:15576 |
| References |
|---|
| General References
| Not Available |