Identification
HMDB Protein ID CDBP04516
Secondary Accession Numbers Not Available
Name AXL receptor tyrosine kinase
Description Not Available
Synonyms Not Available
Gene Name AXL
Protein Type Enzyme
Biological Properties
General Function Not Available
Specific Function ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate
GO Classification
Function
adenyl nucleotide binding
atp binding
protein-tyrosine kinase activity
protein kinase activity
purine nucleotide binding
binding
nucleotide binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
Process
biopolymer metabolism
biopolymer modification
protein modification
physiological process
metabolism
macromolecule metabolism
protein amino acid phosphorylation
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:19
Locus 19q13.1
SNPs Q8N5L2
Gene Sequence
>2685 bp
ATGGCGTGGCGGTGCCCCAGGATGGGCAGGGTCCCGCTGGCCTGGTGCTTGGCGCTGTGC
GGCTGGGCGTGCATGGCCCCCAGGGGCACGCAGGCTGAAGAAAGTCCCTTCGTGGGCAAC
CCAGGGAATATCACAGGTGCCCGGGGACTCACGGGCACCCTTCGGTGTCAGCTCCAGGTT
CAGGGAGAGCCCCCCGAGGTACATTGGCTTCGGGATGGACAGATCCTGGAGCTCGCGGAC
AGCACCCAGACCCAGGTGCCCCTGGGTGAGGATGAACAGGATGACTGGATAGTGGTCAGC
CAGCTCAGAATCACCTCCCTGCAGCTTTCCGACACGGGACAGTACCAGTGTTTGGTGTTT
CTGGGACATCAGACCTTCGTGTCCCAGCCTGGCTATGTTGGGCTGGAGGGCTTGCCTTAC
TTCCTGGAGGAGCCCGAAGACAGGACTGTGGCCGCCAACACCCCCTTCAACCTGAGCTGC
CAAGCTCAGGGACCCCCAGAGCCCGTGGACCTACTCTGGCTCCAGGATGCTGTCCCCCTG
GCCACGGCTCCAGGTCACGGCCCCCAGCGCAGCCTGCATGTTCCAGGGCTGAACAAGACA
TCCTCTTTCTCCTGCGAAGCCCATAACGCCAAGGGGGTCACCACATCCCGCACAGCCACC
ATCACAGTGCTCCCCCAGCAGCCCCGTAACCTCCACCTGGTCTCCCGCCAACCCACGGAG
CTGGAGGTGGCTTGGACTCCAGGCCTGAGCGGCATCTACCCCCTGACCCACTGCACCCTG
CAGGCTGTGCTGTCAGACGATGGGATGGGCATCCAGGCGGGAGAACCAGACCCCCCAGAG
GAGCCCCTCACCTCGCAAGCATCCGTGCCCCCCCATCAGCTTCGGCTAGGCAGCCTCCAT
CCTCACACCCCTTATCACATCCGCGTGGCATGCACCAGCAGCCAGGGCCCCTCATCCTGG
ACCCACTGGCTTCCTGTGGAGACGCCGGAGGGAGTGCCCCTGGGCCCCCCTGAGAACATT
AGTGCTACGCGGAATGGGAGCCAGGCCTTCGTGCATTGGCAAGAGCCCCGGGCGCCCCTG
CAGGGTACCCTGTTAGGGTACCGGCTGGCGTATCAAGGCCAGGACACCCCAGAGGTGCTA
ATGGACATAGGGCTAAGGCAAGAGGTGACCCTGGAGCTGCAGGGGGACGGGTCTGTGTCC
AATCTGACAGTGTGTGTGGCAGCCTACACTGCTGCTGGGGATGGACCCTGGAGCCTCCCA
GTACCCCTGGAGGCCTGGCGCCCAGGGCAAGCACAGCCAGTCCACCAGCTGGTGAAGGAA
CCTTCAACTCCTGCCTTCTCGTGGCCCTGGTGGTATGTACTGCTAGGAGCAGTCGTGGCC
GCTGCCTGTGTCCTCATCTTGGCTCTCTTCCTTGTCCACCGGCGAAAGAAGGAGACCCGT
TATGGAGAAGTGTTTGAACCAACAGTGGAAAGAGGTGAACTGGTAGTCAGGTACCGCGTG
CGCAAGTCCTACAGTCGTCGGACCACTGAAGCTACCTTGAACAGCTTGGGCATCAGTGAA
GAGCTGAAGGAGAAGCTGCGGGATGTGATGGTGGACCGGCACAAGGTGGCCCTGGGGAAG
ACTCTGGGAGAGGGAGAGTTTGGAGCTGTGATGGAAGGCCAGCTCAACCAGGACGACTCC
ATCCTCAAGGTGGCTGTGAAGACGATGAAGATTGCCATCTGCACGAGGTCAGAGCTGGAG
GATTTCCTGAGTGAAGCGGTCTGCATGAAGGAATTTGACCATCCCAACGTCATGAGGCTC
ATCGGTGTCTGTTTCCAGGGTTCTGAACGAGAGAGCTTCCCAGCACCTGTGGTCATCTTA
CCTTTCATGAAACATGGAGACCTACACAGCTTCCTCCTCTATTCCCGGCTCGGGGACCAG
CCAGTGTACCTGCCCACTCAGATGCTAGTGAAGTTCATGGCAGACATCGCCAGTGGCATG
GAGTATCTGAGTACCAAGAGATTCATACACCGGGACCTGGCGGCCAGGAACTGCATGCTG
AATGAGAACATGTCCGTGTGTGTGGCGGACTTCGGGCTCTCCAAGAAGATCTACAATGGG
GACTACTACCGCCAGGGACGTATCGCCAAGATGCCAGTCAAGTGGATTGCCATTGAGAGT
CTAGCTGACCGTGTCTACACCAGCAAGAGCGATGTGTGGTCCTTCGGGGTGACAATGTGG
GAGATTGCCACAAGAGGCCAAACCCCATATCCGGGCGTGGAGAACAGCGAGATTTATGAC
TATCTGCGCCGGGGAAATCGCCTGAAGCAGCCTGCGGACTGTCTGGATGGACTGTATGCC
TTGATGTCGCGGTGCTGGGAGCTAAATCCCCAGGACCGGCCAAGTTTTACAGAGCTGCGG
GAAGATTTGGAGAACACACTGAAGGCCTTGCCTCCTGCCCAGGAGCCTGACGAAATCCTC
TATGTCAACATGGATGAGGGTGGAGGTTATCCTGAACCCCCTGGAGCTGCAGGAGGAGCT
GACCCCCCAACCCAGCCAGACCCTAAGGATTCCTGTAGCTGCCTCACTGCGGCTGAGGTC
CATCCTGCTGGACGCTATGTCCTCTGCCCTTCCACAACCCCTAGCCCCGCTCAGCCTGCT
GATAGGGGCTCCCCAGCAGCCCCAGGGCAGGAGGATGGTGCCTGA
Protein Properties
Number of Residues 894
Molecular Weight 98366.0
Theoretical pI 5.11
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>AXL receptor tyrosine kinase
MAWRCPRMGRVPLAWCLALCGWACMAPRGTQAEESPFVGNPGNITGARGLTGTLRCQLQV
QGEPPEVHWLRDGQILELADSTQTQVPLGEDEQDDWIVVSQLRITSLQLSDTGQYQCLVF
LGHQTFVSQPGYVGLEGLPYFLEEPEDRTVAANTPFNLSCQAQGPPEPVDLLWLQDAVPL
ATAPGHGPQRSLHVPGLNKTSSFSCEAHNAKGVTTSRTATITVLPQQPRNLHLVSRQPTE
LEVAWTPGLSGIYPLTHCTLQAVLSDDGMGIQAGEPDPPEEPLTSQASVPPHQLRLGSLH
PHTPYHIRVACTSSQGPSSWTHWLPVETPEGVPLGPPENISATRNGSQAFVHWQEPRAPL
QGTLLGYRLAYQGQDTPEVLMDIGLRQEVTLELQGDGSVSNLTVCVAAYTAAGDGPWSLP
VPLEAWRPGQAQPVHQLVKEPSTPAFSWPWWYVLLGAVVAAACVLILALFLVHRRKKETR
YGEVFEPTVERGELVVRYRVRKSYSRRTTEATLNSLGISEELKEKLRDVMVDRHKVALGK
TLGEGEFGAVMEGQLNQDDSILKVAVKTMKIAICTRSELEDFLSEAVCMKEFDHPNVMRL
IGVCFQGSERESFPAPVVILPFMKHGDLHSFLLYSRLGDQPVYLPTQMLVKFMADIASGM
EYLSTKRFIHRDLAARNCMLNENMSVCVADFGLSKKIYNGDYYRQGRIAKMPVKWIAIES
LADRVYTSKSDVWSFGVTMWEIATRGQTPYPGVENSEIYDYLRRGNRLKQPADCLDGLYA
LMSRCWELNPQDRPSFTELREDLENTLKALPPAQEPDEILYVNMDEGGGYPEPPGAAGGA
DPPTQPDPKDSCSCLTAAEVHPAGRYVLCPSTTPSPAQPADRGSPAAPGQEDGA
GenBank ID Protein 21619004
UniProtKB/Swiss-Prot ID P30530
UniProtKB/Swiss-Prot Entry Name Q8N5L2_HUMAN
PDB IDs Not Available
GenBank Gene ID BC032229
GeneCard ID Q8N5L2
GenAtlas ID AXL
HGNC ID HGNC:905
References
General References Not Available