| Identification |
|---|
| HMDB Protein ID
| CDBP04515 |
| Secondary Accession Numbers
| Not Available |
| Name
| ROR1 protein |
| Description
| Not Available |
| Synonyms
|
- SubName: Receptor tyrosine kinase-like orphan receptor 1
- SubName: Receptor tyrosine kinase-like orphan receptor 1, isoform CRA_b
|
| Gene Name
| ROR1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Not Available |
| GO Classification
|
| Component |
| integral to plasma membrane |
| cell part |
| membrane part |
| intrinsic to membrane |
| integral to membrane |
| Function |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| protein binding |
| protein kinase activity |
| protein tyrosine kinase activity |
| transmembrane receptor protein tyrosine kinase activity |
| binding |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| enzyme linked receptor protein signaling pathway |
| transmembrane receptor protein tyrosine kinase signaling pathway |
| metabolic process |
| cellular metabolic process |
| protein amino acid phosphorylation |
| signaling |
| signaling pathway |
| cell surface receptor linked signaling pathway |
| phosphorylation |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1p32-p31 |
| SNPs
| ROR1 |
| Gene Sequence
|
>1182 bp
ATGCACCGGCCGCGCCGCCGCGGGACGCGCCCGCCGCTCCTGGCGCTGCTGGCCGCGCTG
CTGCTGGCCGCACGCGGGGCTGCTGCCCAAGAAACAGAGCTGTCAGTCAGTGCTGAATTA
GTGCCTACCTCATCATGGAACATCTCAAGTGAACTCAACAAAGATTCTTACCTGACCCTC
GATGAACCAATGAATAACATCACCACGTCTCTGGGCCAGACAGCAGAACTGCACTGCAAA
GTCTCTGGGAATCCACCTCCCACCATCCGCTGGTTCAAAAATGATGCTCCTGTGGTCCAG
GAGCCCCGGAGGCTCTCCTTTCGGTCCACCATCTATGGCTCTCGGCTGCGGATTAGAAAC
CTCGACACCACAGACACAGGCTACTTCCAGTGCGTGGCAACAAACGGCAAGGAGGTGGTT
TCTTCCACTGGAGTCTTGTTTGTCAAGTTTGGCCCCCCTCCCACTGCAAGTCCAGGATAC
TCAGATGAGTATGAAGAAGATGGATTCTGTCAGCCATACAGAGGGATTGCATGTGCAAGA
TTTATTGGCAACCGCACCGTCTATATGGAGTCTTTGCACATGCAAGGGGAAATAGAAAAT
CAGATCACAGCTGCCTTCACTATGATTGGCACTTCCAGTCACTTATCTGATAAGTGTTCT
CAGTTCGCCATTCCTTCCCTGTGCCACTATGCCTTCCCGTACTGCGATGAAACTTCATCC
GTCCCAAAGCCCCGTGACTTGTGTCGCGATGAATGTGAAATCCTGGAGAATGTCCTGTGT
CAAACAGAGTACATTTTTGCAAGATCAAATCCCATGATTCTGATGAGGCTGAAACTGCCA
AACTGTGAAGATCTCCCCCAGCCAGAGAGCCCAGAAGCTGCGAACTGTATCCGGATTGGA
ATTCCCATGGCAGATCCTATAAATAAAAATCACAAGTGTTATAACAGCACAGGTGTGGAC
TACCGGGGGACCGTCAGTGTGACCAAATCAGGGCGCCAGTGCCAGCCATGGAATTCCCAG
TATCCCCACACACACACTTTCACCGCCCTTCGTTTCCCAGAGCTGAATGGAGGCCATTCC
TACTGCCGCAACCCAGGGAATCAAAAGGAAGCTCCCTGGTGCTTCACCTTGGATGAAAAC
TTTAAGTCTGATCTGTGTGACATCCCAGCGTGCGGTAAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 393 |
| Molecular Weight
| 43825.1 |
| Theoretical pI
| 6.75 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>ROR1 protein
MHRPRRRGTRPPLLALLAALLLAARGAAAQETELSVSAELVPTSSWNISSELNKDSYLTL
DEPMNNITTSLGQTAELHCKVSGNPPPTIRWFKNDAPVVQEPRRLSFRSTIYGSRLRIRN
LDTTDTGYFQCVATNGKEVVSSTGVLFVKFGPPPTASPGYSDEYEEDGFCQPYRGIACAR
FIGNRTVYMESLHMQGEIENQITAAFTMIGTSSHLSDKCSQFAIPSLCHYAFPYCDETSS
VPKPRDLCRDECEILENVLCQTEYIFARSNPMILMRLKLPNCEDLPQPESPEAANCIRIG
IPMADPINKNHKCYNSTGVDYRGTVSVTKSGRQCQPWNSQYPHTHTFTALRFPELNGGHS
YCRNPGNQKEAPWCFTLDENFKSDLCDIPACGK
|
| External Links |
|---|
| GenBank ID Protein
| 56204173 |
| UniProtKB/Swiss-Prot ID
| Q01973 |
| UniProtKB/Swiss-Prot Entry Name
| Q66K77_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AL137859 |
| GeneCard ID
| ROR1 |
| GenAtlas ID
| ROR1 |
| HGNC ID
| HGNC:10256 |
| References |
|---|
| General References
| Not Available |