Showing Protein Ephrin type-A receptor 10 (CDBP04512)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP04512
Secondary Accession Numbers Not Available
Name Ephrin type-A receptor 10
Description Not Available
Synonyms Not Available
Gene Name EPHA10
Protein Type Enzyme
Biological Properties
General Function Involved in ephrin receptor activity
Specific Function Receptor for members of the ephrin-A family. Binds to EFNA3, EFNA4 and EFNA5
GO Classification
Component
integral to plasma membrane
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
ephrin receptor activity
protein binding
protein kinase activity
protein tyrosine kinase activity
transmembrane receptor protein tyrosine kinase activity
binding
catalytic activity
transferase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleoside binding
Process
cell surface receptor linked signaling pathway
phosphorylation
phosphorus metabolic process
phosphate metabolic process
enzyme linked receptor protein signaling pathway
transmembrane receptor protein tyrosine kinase signaling pathway
metabolic process
cellular metabolic process
protein amino acid phosphorylation
signaling
signaling pathway
Cellular Location
  1. Isoform 2:Secreted (Probable)
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 1p34.3
SNPs EPHA10
Gene Sequence 
>3027 bp
ATGGAGACCTGCGCCGGTCCACACCCGCTGCGCCTCTTCCTCTGCCGGATGCAGCTCTGT
CTCGCGCTGCTTTTGGGACCCTGGCGGCCTGGGACCGCCGAGGAAGTTATCCTCCTGGAT
TCCAAAGCCTCCCAGGCCGAGCTGGGCTGGACTGCACTGCCAAGTAATGGGTGGGAGGAG
ATCAGCGGCGTGGATGAACACGACCGTCCCATCCGCACGTACCAAGTGTGCAATGTGCTG
GAGCCCAACCAGGACAACTGGCTGCAGACTGGCTGGATAAGCCGTGGCCGCGGGCAGCGC
ATCTTCGTGGAACTGCAGTTCACACTCCGTGACTGCAGCAGCATCCCTGGCGCCGCGGGT
ACCTGCAAGGAGACCTTCAACGTCTACTACCTGGAAACTGAGGCCGACCTGGGCCGTGGG
CGTCCCCGCCTAGGCGGCAGCCGGCCCCGCAAAATCGACACGATCGCGGCGGACGAGAGC
TTCACGCAGGGCGACCTGGGTGAGCGCAAGATGAAGCTGAACACAGAGGTGCGCGAGATC
GGACCGCTCAGCCGGCGGGGTTTCCACCTGGCCTTTCAGGACGTGGGCGCATGCGTGGCG
CTTGTCTCGGTGCGCGTCTACTACAAGCAGTGCCGCGCCACCGTGCGGGGCCTGGCCACG
TTCCCAGCCACCGCAGCCGAGAGCGCCTTCTCCACACTGGTGGAAGTGGCCGGAACGTGC
GTGGCGCACTCGGAAGGGGAGCCTGGCAGCCCCCCACGCATGCACTGCGGCGCCGACGGC
GAGTGGCTGGTGCCTGTGGGCCGCTGCAGCTGCAGCGCGGGATTCCAGGAGCGTGGTGAC
TTCTGCGAAGCCTGTCCCCCAGGGTTTTACAAGGTGTCCCCGCGGCGGCCCCTCTGCTCA
CCGTGCCCAGAGCACAGCCGGGCCCTGGAAAACGCCTCCACCTTCTGCGTGTGCCAGGAC
AGCTATGCGCGCTCACCCACCGACCCGCCCTCGGCTTCCTGCACCCGGCCGCCGTCGGCG
CCGCGGGACCTGCAGTACAGCCTGAGCCGCTCGCCGCTGGTGCTGCGACTGCGCTGGCTG
CCGCCGGCCGACTCGGGAGGCCGCTCGGACGTCACCTACTCGCTGCTGTGCCTGCGCTGC
GGCCGCGAGGGCCCGGCGGGCGCCTGCGAGCCGTGCGGGCCGCGCGTGGCCTTCCTACCG
CGCCAGGCAGGGCTGCGGGAGCGAGCCGCCACGCTGCTGCACCTGCGGCCCGGCGCGCGC
TACACCGTGCGCGTGGCCGCGCTCAACGGCGTCTCGGGCCCGGCGGCCGCCGCGGGAACC
ACCTACGCGCAGGTCACCGTCTCCACCGGGCCCGGGGCGCCCTGGGAGGAGGATGAGATC
CGCAGGGACCGAGTGGAACCCCAGAGCGTGTCCCTGTCGTGGCGGGAGCCCATCCCTGCC
GGAGCCCCTGGGGCCAATGACACGGAGTACGAGATCCGATACTACGAGAAGGGTCAGAGT
GAGCAGACTTACTCCATGGTGAAGACAGGGGCGCCCACAGTCACCGTCACCAACCTGAAG
CCGGCTACCCGCTACGTCTTTCAGATCCGGGCCGCTTCCCCGGGGCCATCCTGGGAGGCC
CAGAGTTTTAACCCCAGCATTGAAGTACAGACCCTGGGGGAGGCTGCCTCAGGGTCCAGG
GACCAGAGCCCCGCCATTGTCGTCACCGTAGTGACCATCTCGGCCCTCCTCGTCCTGGGC
TCCGTGATGAGTGTGCTGGCCATTTGGAGGAGGCCCTGCAGCTATGGCAAAGGAGGAGGG
GATGCCCATGATGAAGAGGAGCTGTATTTCCACTTCAAAGTCCCAACACGTCGCACATTC
CTGGACCCCCAGAGCTGTGGGGACCTGCTGCAGGCTGTGCATCTGTTCGCCAAGGAACTG
GATGCGAAAAGCGTCACGCTGGAGAGGAGCCTTGGAGGAGGGCGGTTTGGGGAGCTGTGC
TGTGGCTGCTTGCAGCTCCCCGGTCGCCAGGAGCTGCTCGTAGCCGTGCATATGCTGAGG
GACAGCGCCTCCGACTCACAGAGGCTCGGCTTCCTGGCCGAGGCCCTCACGCTGGGCCAG
TTTGACCATAGCCACATCGTGCGGCTGGAGGGCGTTGTTACCCGAGGAAGCACCTTGATG
ATTGTCACCGAGTACATGAGCCATGGGGCCCTGGACGGCTTCCTCAGGCGGCACGAGGGG
CAGCTGGTGGCTGGGCAACTGATGGGGTTGCTGCCTGGGCTGGCATCAGCCATGAAGTAT
CTGTCAGAGATGGGCTACGTTCACCGGGGCCTGGCAGCTCGCCATGTGCTGGTCAGCAGC
GACCTTGTCTGCAAGATCTCTGGCTTCGGGCGGGGCCCCCGGGACCGATCAGAGGCTGTC
TACACCACTATGAGTGGCCGGAGCCCAGCGCTATGGGCCGCTCCCGAGACACTTCAGTTT
GGCCACTTCAGCTCTGCCAGTGACGTGTGGAGCTTCGGCATCATCATGTGGGAGGTGATG
GCCTTTGGGGAGCGGCCTTACTGGGACATGTCTGGCCAAGACGTGATCAAGGCTGTGGAG
GATGGCTTCCGGCTGCCACCCCCCAGGAACTGTCCTAACCTTCTGCACCGACTAATGCTC
GACTGCTGGCAGAAGGACCCAGGTGAGCGGCCCAGGTTCTCCCAGATCCACAGCATCCTG
AGCAAGATGGTGCAGGACCCAGAGCCCCCCAAGTGTGCCCTGACTACCTGTCCCAGGCCT
CCCACCCCACTAGCGGACCGTGCCTTCTCCACCTTCCCCTCCTTTGGCTCTGTGGGCGCG
TGGCTGGAGGCCCTGGACCTGTGCCGCTACAAGGACAGCTTCGCGGCTGCTGGCTATGGG
AGCCTGGAGGCCGTGGCCGAGATGACTGCCCAGGACCTGGTGAGCCTAGGCATCTCTTTG
GCTGAACATCGAGAGGCCCTCCTCAGCGGGATCAGCGCCCTGCAGGCACGAGTGCTCCAG
CTGCAGGGCCAGGGGGTGCAGGTGTGA
Protein Properties
Number of Residues 1008
Molecular Weight 109626.7
Theoretical pI 7.01
Pfam Domain Function
Signals
  • ["1-33"]
Transmembrane Regions
  • ["566-586"]
Protein Sequence 
>Ephrin type-A receptor 10
METCAGPHPLRLFLCRMQLCLALLLGPWRPGTAEEVILLDSKASQAELGWTALPSNGWEE
ISGVDEHDRPIRTYQVCNVLEPNQDNWLQTGWISRGRGQRIFVELQFTLRDCSSIPGAAG
TCKETFNVYYLETEADLGRGRPRLGGSRPRKIDTIAADESFTQGDLGERKMKLNTEVREI
GPLSRRGFHLAFQDVGACVALVSVRVYYKQCRATVRGLATFPATAAESAFSTLVEVAGTC
VAHSEGEPGSPPRMHCGADGEWLVPVGRCSCSAGFQERGDFCEACPPGFYKVSPRRPLCS
PCPEHSRALENASTFCVCQDSYARSPTDPPSASCTRPPSAPRDLQYSLSRSPLVLRLRWL
PPADSGGRSDVTYSLLCLRCGREGPAGACEPCGPRVAFLPRQAGLRERAATLLHLRPGAR
YTVRVAALNGVSGPAAAAGTTYAQVTVSTGPGAPWEEGEIRRDRVEPQSVSLSWREPIPA
GAPGANDTEYEIRYYEKGQSEQAYSMVKTGAPTVTVTNLKPATRYVFQIRAASPGPSWEA
QSFNPSIEVQTLGEAASGSRDQSPAIVVTVVTISALLVLGSVMSVLAIWRRPCSYGKGGG
DAHDEEELYFHFKVPTRRTFLDPQSCGDLLQAVHLFAKELDAKSVTLERSLGGGRFGELC
CGCLQLPGRQELLVAVHMLRDSASDSQRLGFLAEALTLGQFDHSHIVRLEGVVTRGSTLM
IVTEYMSHGALDGFLRRHEGQLVAGQLMGLLPGLASAMKYLSEMGYVHRGLAARHVLVSS
DLVCKISGFGRGPRDRSEAVYTTMSGRSPALWAAPETLQFGHFSSASDVWSFGIIMWEVM
AFGERPYWDMSGQDVIKAVEDGFRLPPPRNCPNLLHRLMLDCWQKDPGERPRFSQIHSIL
SKMVQDPEPPKCALTTCPRPPTPLADRAFSTFPSFGSVGAWLEALDLCRYKDSFAAAGYG
SLEAVAEMTAQDLVSLGISLAEHREALLSGISALQARVLQLQGQGVQV
GenBank ID Protein 150456460
UniProtKB/Swiss-Prot ID Q5JZY3
UniProtKB/Swiss-Prot Entry Name EPHAA_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_001099439.1
GeneCard ID EPHA10
GenAtlas ID EPHA10
HGNC ID HGNC:19987
References
General References Not Available