Identification |
HMDB Protein ID
| CDBP04510 |
Secondary Accession Numbers
| Not Available |
Name
| EPH receptor A8 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| EPHA8 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in ephrin receptor activity |
Specific Function
| Not Available |
GO Classification
|
Component |
integral to plasma membrane |
membrane |
cell part |
membrane part |
intrinsic to membrane |
integral to membrane |
Function |
purine nucleoside binding |
adenyl nucleotide binding |
adenyl ribonucleotide binding |
atp binding |
ephrin receptor activity |
protein binding |
protein kinase activity |
protein tyrosine kinase activity |
transmembrane receptor protein tyrosine kinase activity |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
nucleoside binding |
Process |
cell surface receptor linked signaling pathway |
phosphorylation |
phosphorus metabolic process |
phosphate metabolic process |
enzyme linked receptor protein signaling pathway |
transmembrane receptor protein tyrosine kinase signaling pathway |
metabolic process |
cellular metabolic process |
protein amino acid phosphorylation |
signaling |
signaling pathway |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 1p36.12 |
SNPs
| EPHA8 |
Gene Sequence
|
>1488 bp
ATGGCCCCCGCCCGGGGCCGCCTGCCCCCTGCGCTCTGGGTCGTCACGGCCGCGGCGGCG
GCGGCCACCTGCGTGTCCGCGGCGCGCGGCGAAGTGAATTTGCTGGACACGTCGACCATC
CACGGGGACTGGGGCTGGCTCACGTATCCGGCTCATGGGTGGGACTCCATCAACGAGGTG
GACGAGTCCTTCCAGCCCATCCACACGTACCAGGTTTGCAACGTCATGAGCCCCAACCAG
AACAACTGGCTGCGCACGAGCTGGGTCCCCCGAGACGGCGCCCGGCGCGTCTATGCTGAG
ATCAAGTTTACCCTGCGCGACTGCAACAGCATGCCTGGTGTGCTGGGCACCTGCAAGGAG
ACCTTCAACCTCTACTACCTGGAGTCGGACCGCGACCTGGGGGCCAGCACACAAGAAAGC
CAGTTCCTCAAAATCGACACCATTGCGGCCGACGAGAGCTTCACAGGTGCCGACCTTGGT
GTGCGGCGTCTCAAGCTCAACACGGAGGTGCGCAGTGTGGGTCCCCTCAGCAAGCGCGGC
TTCTACCTGGCCTTCCAGGACATAGGTGCCTGCCTGGCCATCCTCTCTCTCCGCATCTAC
TATAAGAAGTGCCCTGCCATGGTGCGCAATCTGGCTGCCTTCTCGGAGGCAGTGACGGGG
GCCGACTCGTCCTCACTGGTGGAGGTGAGGGGCCAGTGCGTGCGGCACTCAGAGGAGCGG
GACACACCCAAGATGTACTGCAGCGCGGAGGGCGAGTGGCTCGTGCCCATCGGCAAATGC
GTGTGCAGTGCCGGCTACGAGGAGCGGCGGGATGCCTGTGTGGCCTGTGAGCTGGGCTTC
TACAAGTCAGCCCCTGGGGACCAGCTGTGTGCCCGCTGCCCTCCCCACAGCCACTCCGCA
GCTCCAGCCGCCCAAGCCTGCCACTGTGACCTCAGCTACTACCGTGCAGCCCTGGACCCG
CCGTCCTCAGCCTGCACCCGGCCACCCTCGGCACCAGTGAACCTGATCTCCAGTGTGAAT
GGGACATCAGTGACTCTGGAGTGGGCCCCTCCCCTGGACCCAGGTGGCCGCAGTGACATC
ACCTACAATGCCGTGTGCCGCCGCTGCCCCTGGGCACTGAGCCGCTGCGAGGCATGTGGG
AGCGGCACCCGCTTTGTGCCCCAGCAGACAAGCCTGGTGCAGGCCAGCCTGCTGGTGGCC
AACCTGCTGGCCCACATGAACTACTCCTTCTGGATCGAGGCCGTCAATGGCGTGTCCGAC
CTGAGCCCCGAGCCCCGCCGGGCCGCTGTGGTCAACATCACCACGAACCAGGCAGGTAGG
CGGAGAAACTCCGTCCCGCAGCGTCCTGGTCCCCCAGCTTCCCCTGCCTCAGACCCATCC
AGGGATCAGAGCTCTGCCGGGGACGTGCTGTGGGCCTTTAGGCAAGTGCCTCTCTGGCCC
TGCGCTCCTCACCAGGACCCAGAGCTGGAGGCTCTTCATTGCCTTTAG
|
Protein Properties |
Number of Residues
| 495 |
Molecular Weight
| 53899.3 |
Theoretical pI
| 6.79 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>EPH receptor A8
MAPARGRLPPALWVVTAAAAAATCVSAARGEVNLLDTSTIHGDWGWLTYPAHGWDSINEV
DESFQPIHTYQVCNVMSPNQNNWLRTSWVPRDGARRVYAEIKFTLRDCNSMPGVLGTCKE
TFNLYYLESDRDLGASTQESQFLKIDTIAADESFTGADLGVRRLKLNTEVRSVGPLSKRG
FYLAFQDIGACLAILSLRIYYKKCPAMVRNLAAFSEAVTGADSSSLVEVRGQCVRHSEER
DTPKMYCSAEGEWLVPIGKCVCSAGYEERRDACVACELGFYKSAPGDQLCARCPPHSHSA
APAAQACHCDLSYYRAALDPPSSACTRPPSAPVNLISSVNGTSVTLEWAPPLDPGGRSDI
TYNAVCRRCPWALSRCEACGSGTRFVPQQTSLVQASLLVANLLAHMNYSFWIEAVNGVSD
LSPEPRRAAVVNITTNQAGRRRNSVPQRPGPPASPASDPSRDQSSAGDVLWAFRQVPLWP
CAPHQDPELEALHCL
|
External Links |
GenBank ID Protein
| 56417854 |
UniProtKB/Swiss-Prot ID
| P29322 |
UniProtKB/Swiss-Prot Entry Name
| Q8IUX6_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL035703 |
GeneCard ID
| EPHA8 |
GenAtlas ID
| EPHA8 |
HGNC ID
| HGNC:3391 |
References |
General References
| Not Available |