Cannabis Compound Database: Showing Protein Bone morphogenetic protein 1 (CDBP04503)

Identification Biological properties Gene properties Protein properties External links References XML Show 1 compounds

Identification

HMDB Protein ID

CDBP04503

Secondary Accession Numbers

Not Available

Name

Bone morphogenetic protein 1

Description

Not Available

Synonyms

BMP-1
Mammalian tolloid protein
PCP
Procollagen C-proteinase
mTld

Gene Name

BMP1

Protein Type

Enzyme

Biological Properties

General Function

Involved in calcium ion binding

Specific Function

Cleaves the C-terminal propeptides of procollagen I, II and III. Induces cartilage and bone formation. May participate in dorsoventral patterning during early development by cleaving chordin (CHRD)

GO Classification

Function
catalytic activity
hydrolase activity
transition metal ion binding
zinc ion binding
metalloendopeptidase activity
peptidase activity
peptidase activity, acting on l-amino acid peptides
metallopeptidase activity
calcium ion binding
endopeptidase activity
ion binding
cation binding
metal ion binding
binding
Process
metabolic process
macromolecule metabolic process
protein metabolic process
proteolysis

Cellular Location

Cytoplasmic

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:8

Locus

8p21.3

SNPs

BMP1

Gene Sequence

>2961 bp
ATGCCCGGCGTGGCCCGCCTGCCGCTGCTGCTCGGGCTGCTGCTGCTCCCGCGTCCCGGC
CGGCCGCTGGACTTGGCCGACTACACCTATGACCTGGCGGAGGAGGACGACTCGGAGCCC
CTCAACTACAAAGACCCCTGCAAGGCGGCTGCCTTTCTTGGGGACATTGCCCTGGACGAA
GAGGACCTGAGGGCCTTCCAGGTACAGCAGGCTGTGGATCTCAGACGGCACACAGCTCGT
AAGTCCTCCATCAAAGCTGCAGTTCCAGGAAACACTTCTACCCCCAGCTGCCAGAGCACC
AACGGGCAGCCTCAGAGGGGAGCCTGTGGGAGATGGAGAGGTAGATCCCGTAGCCGGCGG
GCGGCGACGTCCCGACCAGAGCGTGTGTGGCCCGATGGGGTCATCCCCTTTGTCATTGGG
GGAAACTTCACTGGTAGCCAGAGGGCAGTCTTCCGGCAGGCCATGAGGCACTGGGAGAAG
CACACCTGTGTCACCTTCCTGGAGCGCACTGACGAGGACAGCTATATTGTGTTCACCTAT
CGACCTTGCGGGTGCTGCTCCTACGTGGGTCGCCGCGGCGGGGGCCCCCAGGCCATCTCC
ATCGGCAAGAACTGTGACAAGTTCGGCATTGTGGTCCACGAGCTGGGCCACGTCGTCGGC
TTCTGGCACGAACACACTCGGCCAGACCGGGACCGCCACGTTTCCATCGTTCGTGAGAAC
ATCCAGCCAGGGCAGGAGTATAACTTCCTGAAGATGGAGCCTCAGGAGGTGGAGTCCCTG
GGGGAGACCTATGACTTCGACAGCATCATGCATTACGCTCGGAACACATTCTCCAGGGGC
ATCTTCCTGGATACCATTGTCCCCAAGTATGAGGTGAACGGGGTGAAACCTCCCATTGGC
CAAAGGACACGGCTCAGCAAGGGGGACATTGCCCAAGCCCGCAAGCTTTACAAGTGCCCA
GCCTGTGGAGAGACCCTGCAAGACAGCACAGGCAACTTCTCCTCCCCTGAATACCCCAAT
GGCTACTCTGCTCACATGCACTGCGTGTGGCGCATCTCTGTCACACCCGGGGAGAAGATC
ATCCTGAACTTCACGTCCCTGGACCTGTACCGCAGCCGCCTGTGCTGGTACGACTATGTG
GAGGTCCGAGATGGCTTCTGGAGGAAGGCGCCCCTCCGAGGCCGCTTCTGCGGGTCCAAA
CTCCCTGAGCCTATCGTCTCCACTGACAGCCGCCTCTGGGTTGAATTCCGCAGCAGCAGC
AATTGGGTTGGAAAGGGCTTCTTTGCAGTCTACGAAGCCATCTGCGGGGGTGATGTGAAA
AAGGACTATGGCCACATTCAATCGCCCAACTACCCAGACGATTACCGGCCCAGCAAAGTC
TGCATCTGGCGGATCCAGGTGTCTGAGGGCTTCCACGTGGGCCTCACATTCCAGTCCTTT
GAGATTGAGCGCCACGACAGCTGTGCCTACGACTATCTGGAGGTGCGCGACGGGCACAGT
GAGAGCAGCACCCTCATCGGGCGCTACTGTGGCTATGAGAAGCCTGATGACATCAAGAGC
ACGTCCAGCCGCCTCTGGCTCAAGTTCGTCTCTGACGGGTCCATTAACAAAGCGGGCTTT
GCCGTCAACTTTTTCAAAGAGGTGGACGAGTGCTCTCGGCCCAACCGCGGGGGCTGTGAG
CAGCGGTGCCTCAACACCCTGGGCAGCTACAAGTGCAGCTGTGACCCCGGGTACGAGCTG
GCCCCAGACAAGCGCCGCTGTGAGGCTGCTTGTGGCGGATTCCTCACCAAGCTCAACGGC
TCCATCACCAGCCCGGGCTGGCCCAAGGAGTACCCCCCCAACAAGAACTGCATCTGGCAG
CTGGTGGCCCCCACCCAGTACCGCATCTCCCTGCAGTTTGACTTCTTTGAGACAGAGGGC
AATGATGTGTGCAAGTACGACTTCGTGGAGGTGCGCAGTGGACTCACAGCTGACTCCAAG
CTGCATGGCAAGTTCTGTGGTTCTGAGAAGCCCGAGGTCATCACCTCCCAGTACAACAAC
ATGCGCGTGGAGTTCAAGTCCGACAACACCGTGTCCAAAAAGGGCTTCAAGGCCCACTTC
TTCTCAGACAAGGACGAGTGCTCCAAGGATAACGGCGGCTGCCAGCAGGACTGCGTCAAC
ACGTTCGGCAGTTATGAGTGCCAATGCCGCAGTGGCTTCGTCCTCCATGACAACAAGCAC
GACTGCAAAGAAGCCGGCTGTGACCACAAGGTGACATCCACCAGTGGTACCATCACCAGC
CCCAACTGGCCTGACAAGTATCCCAGCAAGAAGGAGTGCACGTGGGCCATCTCCAGCACC
CCCGGGCACCGGGTCAAGCTGACCTTCATGGAGATGGACATCGAGTCCCAGCCTGAGTGT
GCCTACGACCACCTAGAGGTGTTCGACGGGCGAGACGCCAAGGCCCCCGTCCTCGGCCGC
TTCTGTGGGAGCAAGAAGCCCGAGCCCGTCCTGGCCACAGGCAGCCGCATGTTCCTGCGC
TTCTACTCAGATAACTCGGTCCAGCGAAAGGGCTTCCAGGCCTCCCACGCCACAGAGTGC
GGGGGCCAGGTACGGGCAGACGTGAAGACCAAGGACCTTTACTCCCACGCCCAGTTTGGC
GACAACAACTACCCTGGGGGTGTGGACTGTGAGTGGGTCATTGTGGCCGAGGAAGGCTAC
GGCGTGGAGCTCGTGTTCCAGACCTTTGAGGTGGAGGAGGAGACCGACTGCGGCTATGAC
TACATGGAGCTCTTCGACGGCTACGACAGCACAGCCCCCAGGCTGGGGCGCTACTGTGGC
TCAGGGCCTCCTGAGGAGGTGTACTCGGCGGGAGATTCTGTCCTGGTGAAGTTCCACTCG
GATGACACCATCACCAAAAAAGGTTTCCACCTGCGATACACCAGCACCAAGTTCCAGGAC
ACACTCCACAGCAGGAAGTGA

Protein Properties

Number of Residues

986

Molecular Weight

111247.8

Theoretical pI

6.89

Pfam Domain Function

EGF_CA (PF07645 )
CUB; (PF00431 )
Astacin (PF01400 )

Signals

["1-22"]

Transmembrane Regions

["None"]

Protein Sequence

>Bone morphogenetic protein 1
MPGVARLPLLLGLLLLPRPGRPLDLADYTYDLAEEDDSEPLNYKDPCKAAAFLGDIALDE
EDLRAFQVQQAVDLRRHTARKSSIKAAVPGNTSTPSCQSTNGQPQRGACGRWRGRSRSRR
AATSRPERVWPDGVIPFVIGGNFTGSQRAVFRQAMRHWEKHTCVTFLERTDEDSYIVFTY
RPCGCCSYVGRRGGGPQAISIGKNCDKFGIVVHELGHVVGFWHEHTRPDRDRHVSIVREN
IQPGQEYNFLKMEPQEVESLGETYDFDSIMHYARNTFSRGIFLDTIVPKYEVNGVKPPIG
QRTRLSKGDIAQARKLYKCPACGETLQDSTGNFSSPEYPNGYSAHMHCVWRISVTPGEKI
ILNFTSLDLYRSRLCWYDYVEVRDGFWRKAPLRGRFCGSKLPEPIVSTDSRLWVEFRSSS
NWVGKGFFAVYEAICGGDVKKDYGHIQSPNYPDDYRPSKVCIWRIQVSEGFHVGLTFQSF
EIERHDSCAYDYLEVRDGHSESSTLIGRYCGYEKPDDIKSTSSRLWLKFVSDGSINKAGF
AVNFFKEVDECSRPNRGGCEQRCLNTLGSYKCSCDPGYELAPDKRRCEAACGGFLTKLNG
SITSPGWPKEYPPNKNCIWQLVAPTQYRISLQFDFFETEGNDVCKYDFVEVRSGLTADSK
LHGKFCGSEKPEVITSQYNNMRVEFKSDNTVSKKGFKAHFFSDKDECSKDNGGCQQDCVN
TFGSYECQCRSGFVLHDNKHDCKEAGCDHKVTSTSGTITSPNWPDKYPSKKECTWAISST
PGHRVKLTFMEMDIESQPECAYDHLEVFDGRDAKAPVLGRFCGSKKPEPVLATGSRMFLR
FYSDNSVQRKGFQASHATECGGQVRADVKTKDLYSHAQFGDNNYPGGVDCEWVIVAEEGY
GVELVFQTFEVEEETDCGYDYMELFDGYDSTAPRLGRYCGSGPPEEVYSAGDSVLVKFHS
DDTITKKGFHLRYTSTKFQDTLHSRK

External Links

GenBank ID Protein

5453579

UniProtKB/Swiss-Prot ID

P13497

UniProtKB/Swiss-Prot Entry Name

BMP1_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_006129.4

GeneCard ID