Cannabis Compound Database: Showing Protein Dual specificity protein phosphatase 21 (CDBP04501)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP04501

Secondary Accession Numbers

Not Available

Name

Dual specificity protein phosphatase 21

Description

Not Available

Synonyms

LMW-DSP21
Low molecular weight dual specificity phosphatase 21

Gene Name

DUSP21

Protein Type

Enzyme

Biological Properties

General Function

Involved in phosphatase activity

Specific Function

Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.

GO Classification

Cellular Component
cytoplasm
nucleus
mitochondrial inner membrane
Function
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphatase activity
map kinase tyrosine/serine/threonine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
Molecular Function
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
Process
phosphorus metabolic process
phosphate metabolic process
dephosphorylation
protein amino acid dephosphorylation
metabolic process
cellular metabolic process

Cellular Location

Nucleus
Cytoplasm

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

Xp11.4-p11.23

SNPs

DUSP21

Gene Sequence

>573 bp
ATGACAGCATCCGCGTCCTCCTTTTCATCATCTCAGGGTGTCCAGCAGCCCTCCATCTAC
AGCTTCTCCCAAATAACCAGAAGCTTGTTTCTCAGCAATGGTGTGGCCGCCAACGACAAA
CTCCTTCTGTCCAGCAATCGCATCACCGCCATTGTCAATGCCTCGGTGGAAGTGGTCAAC
GTATTCTTCGAGGGCATTCAGTACATAAAGGTGCCTGTTACCGATGCTCGTGACTCGCGT
CTCTACGACTTTTTTGACCCCATTGCTGATCTTATCCACACCATCGATATGAGGCAGGGC
CGTACGCTGCTGCACTGCATGGCTGGAGTGAGCCGTTCCGCCTCACTGTGCCTTGCGTAC
CTCATGAAATACCACTCCATGTCGCTGCTGGACGCCCATACATGGACCAAGTCGCGCCGC
CCCATCATCCGGCCCAACAACGGCTTTTGGGAACAGCTCATCAATTACGAATTCAAGCTG
TTTAATAACAACACCGTGCGCATGATCAACTCGCCGGTAGGTAACATCCCTGACATCTAT
GAGAAGGACCTACGTATGATGATATCAATGTAA

Protein Properties

Number of Residues

190

Molecular Weight

21528.525

Theoretical pI

8.815

Pfam Domain Function

DSPc (PF00782 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Dual specificity protein phosphatase 21
MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN
VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY
EKDLRMMISM

External Links

GenBank ID Protein

24415104

UniProtKB/Swiss-Prot ID

Q9H596

UniProtKB/Swiss-Prot Entry Name

DUS21_HUMAN

PDB IDs

Not Available

GenBank Gene ID

AF533018

GeneCard ID