Showing Protein Dual specificity protein phosphatase 21 (CDBP04501)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP04501
Secondary Accession Numbers Not Available
Name Dual specificity protein phosphatase 21
Description Not Available
Synonyms
  1. LMW-DSP21
  2. Low molecular weight dual specificity phosphatase 21
Gene Name DUSP21
Protein Type Enzyme
Biological Properties
General Function Involved in phosphatase activity
Specific Function Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine.
GO Classification
Cellular Component
cytoplasm
nucleus
mitochondrial inner membrane
Function
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphatase activity
map kinase tyrosine/serine/threonine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
Molecular Function
protein tyrosine phosphatase activity
protein tyrosine/serine/threonine phosphatase activity
MAP kinase tyrosine/serine/threonine phosphatase activity
Process
phosphorus metabolic process
phosphate metabolic process
dephosphorylation
protein amino acid dephosphorylation
metabolic process
cellular metabolic process
Cellular Location
  1. Nucleus
  2. Cytoplasm
Pathways
Gene Properties
Chromosome Location X
Locus Xp11.4-p11.23
SNPs DUSP21
Gene Sequence 
>573 bp
ATGACAGCATCCGCGTCCTCCTTTTCATCATCTCAGGGTGTCCAGCAGCCCTCCATCTAC
AGCTTCTCCCAAATAACCAGAAGCTTGTTTCTCAGCAATGGTGTGGCCGCCAACGACAAA
CTCCTTCTGTCCAGCAATCGCATCACCGCCATTGTCAATGCCTCGGTGGAAGTGGTCAAC
GTATTCTTCGAGGGCATTCAGTACATAAAGGTGCCTGTTACCGATGCTCGTGACTCGCGT
CTCTACGACTTTTTTGACCCCATTGCTGATCTTATCCACACCATCGATATGAGGCAGGGC
CGTACGCTGCTGCACTGCATGGCTGGAGTGAGCCGTTCCGCCTCACTGTGCCTTGCGTAC
CTCATGAAATACCACTCCATGTCGCTGCTGGACGCCCATACATGGACCAAGTCGCGCCGC
CCCATCATCCGGCCCAACAACGGCTTTTGGGAACAGCTCATCAATTACGAATTCAAGCTG
TTTAATAACAACACCGTGCGCATGATCAACTCGCCGGTAGGTAACATCCCTGACATCTAT
GAGAAGGACCTACGTATGATGATATCAATGTAA
Protein Properties
Number of Residues 190
Molecular Weight 21528.525
Theoretical pI 8.815
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Dual specificity protein phosphatase 21
MTASASSFSSSQGVQQPSIYSFSQITRSLFLSNGVAANDKLLLSSNRITAIVNASVEVVN
VFFEGIQYIKVPVTDARDSRLYDFFDPIADLIHTIDMRQGRTLLHCMAGVSRSASLCLAY
LMKYHSMSLLDAHTWTKSRRPIIRPNNGFWEQLINYEFKLFNNNTVRMINSPVGNIPDIY
EKDLRMMISM
GenBank ID Protein 24415104
UniProtKB/Swiss-Prot ID Q9H596
UniProtKB/Swiss-Prot Entry Name DUS21_HUMAN
PDB IDs Not Available
GenBank Gene ID AF533018
GeneCard ID DUSP21
GenAtlas ID DUSP21
HGNC ID HGNC:20476
References
General References Not Available