| Identification |
|---|
| HMDB Protein ID
| CDBP04406 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable E3 ubiquitin-protein ligase MYCBP2 |
| Description
| Not Available |
| Synonyms
|
- Myc-binding protein 2
- Pam/highwire/rpm-1 protein
- Protein associated with Myc
|
| Gene Name
| MYCBP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein binding |
| Specific Function
| Probable E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. May function as a facilitator or regulator of transcriptional activation by MYC. May have a role during synaptogenesis |
| GO Classification
|
| Component |
| macromolecular complex |
| protein complex |
| ubiquitin ligase complex |
| nuclear ubiquitin ligase complex |
| anaphase-promoting complex |
| Function |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| transition metal ion binding |
| zinc ion binding |
| protein binding |
| Process |
| biological regulation |
| regulation of biological process |
| regulation of cell cycle |
| regulation of cellular process |
| regulation of mitotic cell cycle |
| regulation of mitosis |
| regulation of mitotic metaphase/anaphase transition |
|
| Cellular Location
|
- Nucleus
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 13q22 |
| SNPs
| MYCBP2 |
| Gene Sequence
|
>14037 bp
ATGATGATGTGCGCAGCGACTGCCTCCCCCGCCGCCGCCTCCTCGGGGCTCGGCGGGGAC
GGATTCTACCCAGCCGCCACCTTCTCTTCCTCCCCGGCGCCGGGGGCGCTGTTCATGCCG
GTTCCCGACGGCTCCGTGGCTGCTGCGGGGCTGGGGCTGGGGCTACCCGCCGCGGACTCC
CGGGGTCACTACCAGCTGCTGCTGTCAGGCCGGGCCCTGGCCGACCGCTACCGGAGGATT
TATACCGCTGCGCTCAATGACAGGGACCAGGGGGGCGGCAGCGCTGGACACCCAGCCTCC
AGGAATAAGAAAATTTTAAATAAGAAGAAATTGAAAAGAAAACAGAAGAGCAAATCAAAA
GTGAAGACAAGAAGCAAGTCTGAAAACTTAGAGAATACAGTAATCATACCAGATATCAAA
CTACATAGCAATCCTTCTGCTTTCAATATTTACTGTAATGTACGCCATTGCGTTCTGGAA
TGGCAGAAAAAGGAAATATCATTGGCAGCCGCATCTAAGAACTCTGTGCAGAGTGGAGAA
TCAGATAGTGATGAAGAAGAGGAATCCAAAGAGCCCCCTATCAAGCTTCCAAAGATTATT
GAGGTTGGCCTTTGTGAAGTTTTTGAATTGATCAAAGAGACACGATTTTCTCATCCATCC
CTGTGTCTCAGGAGTCTCCAAGCCCTGCTCAACGTGCTGCAGGGCCAGCAGCCAGAAGGC
CTCCAGTCTGAGCCACCTGAGGTCCTAGAGTCTCTCTTCCAGCTTCTTTTGGAAATCACC
GTTCGAAGTACTGGGATGAATGACAGCACAGGACAGTCCTTAACAGCACTTTCCTGTGCT
TGCCTCTTTAGTCTGGTGGCTTCTTGGGGAGAAACAGGAAGGACACTTCAGGCCATCTCT
GCTATCCTCACCAACAATGGAAGCCATGCTTGCCAAACTATTCAGGTGCCAACAATTCTA
AATTCGCTACAGAGAAGTGTACAAGCAGTTTTGGTGGGAAAAATTCAAATTCAGGACTGG
TTTAGTAATGGCATTAAGAAAGCAGCTTTAATGCACAAGTGGCCATTAAAAGAAATATCT
GTTGATGAAGATGACCAATGTCTACTTCAGAATGATGGATTTTTTCTTTATCTATTATGC
AAGGATGGATTATATAAAATAGGCTCTGGATACAGTGGAACAGTTAGGGGCCATATATAC
AATTCTACATCCCGTATTAGAAACAGAAAAGAAAAAAAGTCTTGGTTAGGGTATGCTCAG
GGTTATTTATTATATAGAGATGTGAATAACCACAGCATGACAGCCATAAGGATAAGCCCT
GAAACACTGGAGCAAGATGGTACTGTGATGTTACCAGATTGCCACACTGAAGGTCAAAAT
ATTTTATTCACTGATGGAGAATATATTAATCAGATAGCTGCTTCAAGAGATGATGGCTTT
GTTGTCAGAATATTTGCCACAAGCACTGAACCTGTTCTACAGCAAGAATTGCAACTTAAA
CTGGCTAGAAAATGCTTACATGCCTGTGGTATCTCACTATTCGATCTGGAAAAGGACTTG
CATATTATAAGTACAGGATTTGATGAGGAGTCAGCAATTCTTGGTGCAGGACGAGAGTTT
GCGCTAATGAAAACAGCAAATGGAAAGATATATTACACTGGCAAATACCAGAGTCTTGGA
ATCAAACAAGGTGGTCCTTCAGCAGGAAAATGGGTTGAGCTACCAATTACAAAATCTCCA
AAGATAGTACACTTCTCAGTTGGACACGATGGCTCTCACGCCCTTTTAGTTGCAGAAGAT
GGGAGCATATTCTTTACAGGATCTGCTAGTAAAGGAGAAGATGGAGAATCAACTAAGAGC
AGACGGCAATCCAAACCTTATAAACCTAAAAAGATAATTAAGATGGAAGGAAAGATTGTG
GTATATACAGCCTGCAATAATGGAAGTAGTTCTGTTATTTCTAAAGATGGAGAACTCTAC
ATGTTTGGAAAAGATGCCATTTACTCTGATAGTTCAAGTTTGGTAACTGATTTGAAGGGC
CATTTTGTAACTCAGGTAGCTATGGGCAAAGCTCACACTTGTGTTTTAATGAAGAATGGA
GAGGTGTGGACATTTGGTGTAAATAATAAAGGACAGTGTGGACGAGATACTGGTGCCATG
AACCAAGGTGGGAAAGGGTTTGGAGTTGAAAATATGGCAACAGCAATGGATGAAGACCTG
GAAGAAGAACTAGATGAAAAAGATGAGAAGTCTATGATGTGCCCTCCAGGCATGCACAAA
TGGAAGCTGGAGCAGTGCATGGTTTGCACTGTCTGTGGAGACTGTACAGGTTATGGAGCC
AGCTGTGTCAGTAGTGGACGGCCAGACAGAGTCCCCGGAGGGATCTGTGGTTGTGGTTCC
GGAGAATCTGGTTGTGCTGTGTGTGGATGTTGCAAGGCCTGTGCAAGAGAGTTAGATGGT
CAAGAGGCAAGACAAAGAGGAATTCTTGATGCAGTGAAAGAAATGATACCTTTAGATCTT
CTTTTAGCTGTCCCAGTGCCCGGGGTTAACATTGAAGAACACCTTCAGTTACGACAAGAA
GAAAAACGGCAACGTGTAATCAGAAGGCACAGATTAGAGGAAGGAAGAGGCCCCCTTGTA
TTTGCTGGTCCTATTTTTATGAACCATCGAGAACAGGCTCTAGCCAGACTCAGATCCCAT
CCAGCACAGCTAAAGCATAAACGGGACAAGCACAAAGATGGAAGTGGAGAAAGAGGCGAA
AAGGATGCAAGCAAAATCACAACATACCCTCCAGGCTCTGTGCGATTTGACTGTGAGCTC
CGGGCAGTCCAAGTCAGCTGTGGATTTCACCATTCAGTGGTTTTAATGGAAAATGGAGAT
GTCTATACATTTGGTTATGGGCAGCATGGGCAGCTAGGACATGGAGATGTCAACTCCAGG
GGATGTCCCACTCTTGTTCAAGCATTGCCAGGCCCTAGCACACAAGTCACTGCAGGCAGC
AACCATACGGCAGTACTTTTAATGGATGGACAGGTCTTCACATTTGGAAGTTTTTCTAAA
GGACAACTGGGCAGACCAATTTTGGATGTGCCATATTGGAATGCAAAGCCAGCTCCCATG
CCTAACATTGGATCAAAATATGGAAGAAAAGCTACTTGGATAGGTGCAAGTGGGGACCAA
ACTTTTTTACGAATTGATGAAGCACTTATTAATTCTCATGTACTTGCTACATCAGAAATT
TTTGCCAGTAAACACATAATAGGCTTGGTACCTGCTTCTATATCAGAACCTCCTCCATTT
AAATGCCTTCTGATAAATAAAGTGGATGGGAGTTGTAAAACTTTTAATGACTCAGAACAA
GAGGATCTGCAAGGATTTGGTGTGTGTCTTGATCCTGTATATGATGTAATTTGGAGGTTT
CGACCAAATACTAGAGAGCTGTGGTGTTACAATGCGGTGGTTGCTGATGCCAGGCTTCCC
TCTGCAGCAGACATGCAGTCCAGATGTAGTATCCTAAGTCCTGAACTTGCCTTACCAACA
GGATCAAGGGCCCTCACTACCCGATCTCATGCAGCTTTGCACATTTTAGGTTGTCTTGAT
ACCTTGGCAGCTATGCAGGACTTAAAAATGGGTGTTGCAAGTACAGAGGAAGAGACTCAA
GCAGTAATGAAGGTTTATTCTAAAGAAGATTATAGTGTGGTAAACAGGTTTGAAAGTCAT
GGAGGAGGCTGGGGTTATTCTGCCCATTCAGTAGAAGCTATACGTTTCAGTGCCGACACT
GATATTTTACTTGGTGGTCTTGGTCTGTTTGGAGGTAGAGGAGAATATACTGCTAAAATT
AAGCTGTTTGAATTGGGTCCTGATGGAGGAGATCATGAAACTGATGGTGACCTTCTTGCA
GAGACTGATGTATTGGCTTATGACTGTGCTGCTAGAGAAAAATATGCAATGATGTTTGAT
GAGCCTGTTCTCCTGCAAGCTGGGTGGTGGTATGTGGCATGGGCCCGAGTGTCAGGACCC
AGCAGTGACTGTGGATCTCATGGACAGGCATCTATTACCACAGATGATGGGGTTGTTTTC
CAGTTCAAGAGTTCAAAGAAATCAAATAATGGTACAGATGTTAATGCGGGTCAGATACCT
CAGTTATTATACAGACTTCCAACCAGTGATGGCAGTGCTTCAAAAGGCAAACAGCAAACC
AGTGAACCTGTACACATTTTAAAGAGGTCTTTTGCAAGAACTGTCTCAGTGGAATGTTTT
GAGTCATTGTTGAGTATTCTTCACTGGAGCTGGACCACCTTAGTCTTAGGAGTTGAAGAA
CTTAGAGGATTAAAAGGATTCCAGTTCACAGCTACACTCCTAGATTTAGAGAGACTGCGC
TTTGTGGGTACCTGTTGTCTGAGGTTATTGCGTGTCTATACCTGTGAAATTTACCCAGTG
TCAGCTACAGGAAAAGCAGTTGTAGAAGAAACTAGCAAATTAGCAGAGTGTATTGGAAAA
ACCAGAACTTTGTTAAGAAAAATTTTATCAGAAGGAGTTGATCACTGCATGGTGAAATTG
GATAATGATCCTCAAGGATATCTCAGTCAACCCTTGAGTCTTCTAGAAGCTGTCCTTCAG
GAATGTCATAATACTTTCACTGCCTGCTTTCATTCTTTCTACCCAACTCCTGCCTTACAG
TGGGCTTGCCTTTGTGATCTGCTGAATTGTTTGGATCAGGATATCCAAGAAGCAAACTTC
AAGACATCAAGTAGCCGACTCCTTGCAGCTGTTATGTCAGCTCTGTGTCACACGTCTGTT
AAGCTGACTTCCATCTTCCCGATTGCGTATGATGGAGAAGTATTACTACGATCAATTGTT
AAACAAGTTAGTACAGAGAACGACTCAACACTAGTTCATCGTTTTCCCCTTTTGGTGGCA
CATATGGAAAAACTCAGCCAGAGTGAAGAGAATATCTCAGGGATGACAAGCTTCCGTGAA
GTTCTGGAGAAAATGCTGGTCATTGTTGTGCTACCAGTCAGGAACAGCCTGAGGAGAGAA
AATGAACTCTTCTCCTCCCACCTCGTCTCTAACACCTGTGGATTACTGGCCAGCATTGTC
AGTGAACTGACAGCGTCAGCCCTGGGATCTGAGGTTGATGGACTTAATTCTCTTCACTCT
GTAAAAGCTAGTGCTAACCGATTTACAAAAACAAGTCAGGGCAGAAGTTGGAACACTGGG
AACGGGTCCCCTGATGCAATCTGTTTTTCAGTAGACAAACCTGGAATAGTTGTGGTTGGT
TTCTCTGTCTATGGAGGAGGTGGAATTCATGAATATGAATTAGAGGTGTTGGTTGATGAT
AGTGAACATGCAGGAGATTCAACTCATTCCCACAGATGGACATCTCTGGAATTAGTGAAA
GGAACGTACACAACGGATGACTCACCCAGTGATATAGCTGAGATCAGACTTGACAAAGTG
GTTCCTTTAAAGGAAAATGTTAAATATGCTGTGCGCTTGAGGAACTATGGAAGCCGTACA
GCCAATGGAGATGGAGGAATGACCACAGTTCAGTGCCCTGATGGTGTGACATTCACATTC
AGCACGTGCAGCTTGAGCAGTAACGGCACAAACCAAACCAGAGGACAGATCCCACAGATA
CTCTACTATAGGAGTGAATTTGATGGAGATTTACAATCCCAACTTCTGAGTAAAGCCAAT
GAAGAAGATAAAAACTGTAGCAGAGCATTGTCTGTTGTAAGCACTGTCGTTCGAGCCTCT
AAGGACCTCCTGCACAGAGCTCTTGCTGTGGATGCTGATGACATTCCAGAACTGCTGAGT
TCTTCCAGTCTGTTTTCCATGCTGCTCCCCCTTATTATAGCCTACATAGGACCAGTAGCT
GCTGCTATTCCCAAGGTGGCTGTAGAAGTCTTTGGCCTTGTCCAACAATTGCTTCCGTCA
GTTGCCATTTTGAATCAGAAGTATGCACCGCCTGCCTTCAACCCTAATCAGTCGACAGAT
AGCACCACAGGAAACCAGCCTGAACAGGGCCTCTCTGCTTGTACAACCTCCAGTCACTAT
GCTGTCATAGAGAGTGAGCACCCGTATAAACCTGCCTGTGTGATGCATTACAAGGTGACA
TTCCCAGAATGTGTGAGGTGGATGACAATCGAATTTGACCCTCAGTGTGGTACTGCACAG
TCAGAAGATGTCCTTCGTTTGTTGATTCCTGTCAGAACTGTTCAGAATTCAGGATATGGA
CCAAAATTGACATCTGTTCATGAAAATCTTAATTCATGGATAGAATTAAAGAAATTTTCA
GGATCCTCTGGGTGGCCTACTATGGTTTTGGTGTTGCCAGGAAATGAGGCCCTTTTTTCA
TTGGAGACTGCATCAGATTATGTGAAAGATGACAAAGCTTCTTTCTATGGTTTTAAGTGT
TTTGCAATTGGATATGAATTTAGCCCTGGACCTGATGAGGGAGTCATCCAATTGGAAAAA
GAATTAGCCAATCTTGGTGGGGTTTGTGCAGCAGCTCTGATGAAGAAGGACCTAGCACTT
CCTATTGGTAATGAATTAGAAGAAGACCTTGAAATTCTTGAGGAGGCTGCATTGCAGGTG
TGCAAAACCCATTCTGGAATTCTTGGAAAGGGTCTAGCTCTTTCTCATTCACCAACTATA
TTAGAAGCACTTGAGGGAAATTTACCACTCCAAATCCAAAGCAATGAACAGTCTTTTCTG
GATGATTTTATTGCCTGTGTCCCAGGATCAAGTGGTGGAAGGCTTGCAAGGTGGCTTCAG
CCAGATTCATATGCGGATCCTCAGAAAACATCTTTGATCCTGAATAAGGATGATATTCGT
TGTGGTTGGCCTACCACCATAACTGTTCAAACAAAAGACCAGTATGGGGATGTGGTACAT
GTTCCCAATATGAAGGTGGAAGTGAAAGCTGTCCCTGTTTCTCAGAAAAAAATGTCTTTA
CAACAAGATCAAGCAAAGAAACCTCAAAGGATTCCTGGCAGTCCTGCAGTAACAGCTGCA
TCTTCTAATACTGACATGACTTATGGAGGGCTGGCATCACCAAAGCTAGATGTTTCATAT
GAACCAATGATAGTGAAGGAAGCTCGATATATTGCCATAACAATGATGAAGGTTTATGAA
AATTATTCATTTGAAGAACTACGTTTTGCATCACCAACTCCTAAGAGACCCAGTGAGAAT
ATGCTGATCCGTGTCAATAATGATGGGACTTATTGTGCAAATTGGACTCCAGGGGCTATT
GGACTCTACACTCTTCATGTTACCATTGATGGCATTGAAATCGATGCTGGTCTGGAAGTA
AAAGTAAAAGACCCACCAAAAGGGATGATACCACCAGGAACTCAGTTGGTCAAACCAAAG
TCTGAACCTCAGCCTAATAAGGTTCGAAAATTTGTGGCCAAGGACAGTGCGGGGCTTCGC
ATCCGTAGCCACCCTTCCCTTCAGAGTGAGCAGATAGGCATAGTGAAAGTCAATGGAACT
ATCACTTTTATTGATGAGATCCATAATGATGATGGTGTGTGGCTGAGGCTGAATGATGAG
ACAATAAAGAAGTATGTCCCTAACATGAATGGTTACACTGAAGCCTGGTGCCTCTCTTTT
AATCAACATCTTGGCAAGAGTCTTCTGGTCCCTGTTGACGAATCTAAAACTAATACTGAT
GACTTTTTCAAAGACATAAACTCCTGCTGCCCACAGGAAGCAACAATGCAAGAACAAGAT
ATGCCATTCTTGCGAGGAGGGCCAGGCATGTACAAGGTAGTGAAGACGGGACCTTCAGGT
CACAACATCAGAAGCTGCCCTAACCTTAGAGGTATCCCAATTGGAATGTTAGTTCTGGGA
AACAAAGTCAAAGCAGTGGGAGAGGTAACCAATTCTGAAGGGACATGGGTGCAACTGGAT
CAGAACAGCATGGTAGAGTTCTGTGAGAGTGATGAAGGAGAGGCATGGTCCTTAGCTAGA
GACAGAGGCGGAAACCAGTACCTCCGACATGAAGATGAACAAGCTCTTCTGGATCAGAAT
TCTCAAACTCCTCCTCCAAGCCCTTTCTCAGTGCAAGCTTTTAATAAAGGGGCAAGTTGC
AGTGCCCAAGGATTTGATTATGGACTCGGAAATAGCAAAGGTGATCGAGGAAACATCTCA
ACATCTTCTAAACCAGCCTCTACATCAGGAAAATCAGAGCTGTCCTCTAAACACAGCAGA
TCGCTTAAACCTGATGGACGTATGAGCCGGACTACTGCTGATCAGAAGAAGCCAAGGGGC
ACAGAAAGTTTATCTGCTAGTGAATCCCTCATCTTAAAATCTGATGCTGCAAAGTTGAGG
TCAGATTCCCACAGTAGGTCATTATCCCCCAACCATAACACCTTGCAGACATTGAAATCT
GATGGGAGGATGCCTTCTAGCTCCAGAGCTGAATCCCCAGGACCAGGTTCTCGGTTGTCA
TCTCCTAAGCCAAAGACTCTCCCAGCCAATAGGTCTAGCCCATCGGGTGCTAGTTCTCCA
CGCTCCTCCTCACCACATGATAAAAATCTACCTCAAAAAAGTACTGCTCCTGTTAAGACA
AAGCTTGATCCTCCTCGGGAACGTTCTAAATCAGACTCTTACACACTTGATCCAGATACC
CTCCGCAAGAAGAAAATGCCCCTCACAGAACCTTTGAGAGGACGGTCAACGTCACCAAAA
CCAAAATCAGTACCAAAGGATTCTACAGATTCCCCTGGATCTGAAAATAGAGCTCCCTCT
CCCCATGTGGTACAGGAAAACCTCCACAGTGAGGTGGTCGAAGTCTGCACCTCAAGTACT
TTAAAAACAAATAGTCTAACAGACAGCACCTGCGATGACAGCAGTGAATTTAAGAGTGTG
GATGAAGGTTCAAATAAAGTTCATTTTAGCATTGGAAAAGCACCACTGAAAGATGAACAG
GAAATGAGAGCATCTCCCAAAATAAGTCGAAAATGTGCTAATAGACACACCAGGCCCAAA
AAAGAAAAATCGAGTTTTCTTTTCAAAGGAGATGGATCCAAGCCTTTAGAGCCAGCCAAG
CAAGCCATGTCTCCTTCTGTGGCCGAATGTGCCAGAGCTGTGTTTGCTTCCTTCCTCTGG
CATGAAGGCATAGTACATGATGCAATGGCTTGTTCTTCTTTCCTAAAGTTTCATCCTGAA
CTTTCCAAAGAACATGCTCCTATAAGGAGTAGTTTAAATAGCCAACAACCTACAGAGGAA
AAAGAAACCAAGTTAAAAAATAGACATTCATTAGAAATATCATCTGCACTGAATATGTTT
AATATTGCACCCCATGGACCAGATATATCTAAGATGGGTAGCATCAACAAAAACAAGGTA
TTGTCTATGCTTAAGGAACCACCTCTGCATGAAAAATGTGAGGATGGGAAAACCGAGACC
ACTTTTGAAATGTCCATGCATAACACAATGAAGTCTAAGTCTCCTCTTCCCTTAACTTTA
CAACATTTAGTGGCTTTTTGGGAAGACATCTCTTTGGCTACTATCAAAGCTGCTTCCCAG
AATATGATTTTTCCAAGTCCTGGTTCCTGTGCAGTTCTTAAAAAGAAAGAGTGTGAGAAA
GAGAATAAGAAGTCCAAAAAGGAAAAAAAGAAAAAAGAAAAGGCAGAAGTTAGGCCCAGG
GGTAATTTGTTTGGAGAGATGGCCCAGCTGGCAGTAGGAGGACCAGAGAAAGATACCATC
TGTGAACTGTGTGGGGAGTCACATCCATACCCGGTGACCTATCACATGAGACAAGCTCAC
CCAGGTTGTGGCCGATATGCTGGTGGACAAGGTTACAATAGCATTGGGCATTTTTGTGGA
GGATGGGCTGGTAACTGTGGTGATGGTGGCATAGGAGGAAGCACTTGGTATCTGGTATGT
GATCGCTGTAGAGAAAAATACCTCCGCGAAAAACAGGCTGCTGCAAGGGAGAAGGTCAAA
CAATCTAGGAGAAAACCAATGCAAGTCAAGACCCCTCGTGCCTTGCCCACCATGGAAGCT
CACCAGGTGATTAAAGCCAATGCACTCTTCCTGCTGTCCCTGAGCAGTGCAGCAGAACCG
AGCATTCTGTGTTACCATCCTGCAAAGCCATTCCAATCTCAGTTGCCCAGTGTAAAAGAA
GGCATTTCTGAGGATCTTCCTGTGAAAATGCCTTGTCTCTACCTGCAGACATTAGCTAGG
CATCATCATGAAAATTTTGTGGGCTATCAAGATGACAATCTATTCCAGGATGAAATGAGA
TATCTACGTTCAACATCTGTACCTGCCCCGTATATATCAGTAACTCCTGATGCAAGTCCT
AATGTATTTGAAGAGCCAGAGAGCAATATGAAGTCTATGCCACCAAGTTTAGAAACCAGT
CCCATAACTGATACTGATCTTGCAAAGAGAACTGTCTTCCAAAGATCATACTCAGTTGTT
GCTTCCGAATATGATAAACAACACTCCATTTTACCTGCACGAGTTAAAGCTATTCCTAGA
AGAAGAGTTAACAGTGGAGACACTGAAGTTGGTTCTTCCCTTTTGAGACATCCGTCTCCT
GAGCTTTCTCGGCTAATCTCAGCCCACAGCTCTCTTTCTAAAGGAGAACGAAATTTCCAG
TGGCCAGTTTTAGCTTTTGTTATACAACATCATGATCTAGAAGGTCTTGAAATAGCAATG
AAACAGGCCCTAAGGAAATCTGCTTGTCGAGTTTTTGCTATGGAGGCTTTCAACTGGCTT
CTGTGTAATGTCATCCAAACCACTTCTCTCCATGATATTCTGTGGCATTTTGTGGCATCA
CTGACTCCTGCACCAGTGGAACCAGAGGAAGAAGAGGATGAAGAAAATAAAACAAGCAAA
GAAAATTCAGAACAAGAGAAAGATACAAGAGTATGTGAACATCCACTCTCAGACATAGTG
ATTGCCGGGGAAGCTGCTCATCCTTTACCACACACCTTTCACCGCTTGCTGCAGACCATC
TCAGACCTTATGATGTCTCTCCCCAGCGGCAGTTCATTACAGCAAATGGCCCTGAGGTGC
TGGAGTCTCAAATTCAAGCAATCTGATCACCAGTTCCTTCATCAGAGCAACGTCTTTCAT
CACATTAACAATATTTTGTCAAAGTCAGATGATGGCGATAGTGAAGAGAGTTTTAGCATC
AGTATACAGTCTGGCTTTGAAGCTATGAGTCAGGAATTATGCATAGTAATGTGCTTAAAG
GACTTAACCAGCATTGTTGACATAAAAACTTCAAGCCGACCTGCCATGATTGGCAGTTTG
ACAGACGGCTCCACAGAAACCTTTTGGGAATCAGGAGATGAAGATAAAAACAAAACTAAG
AACATCACCATCAACTGTGTAAAAGGAATCAATGCCCGCTATGTGTCTGTTCACGTGGAC
AATTCCCGAGATCTTGGGAATAAAGTTACCTCAATGACCTTCTTAACTGGCAAAGCAGTA
GAAGATTTGTGCAGAATAAAGCAGGTTGATCTGGATTCCAGGCACATTGGCTGGGTAACA
AGTGAACTTCCAGGAGGGGATAATCACATCATAAAAATTGAATTAAAAGGCCCAGAAAAT
ACACTGAGAGTTCGACAAGTCAAAGTCCTGGGCTGGAAAGATGGTGAAAGCACAAAAATA
GCTGGCCAGATTTCAGCCAGTGTGGCCCAGCAGAGGAACTGTGAAGCTGAGACTCTGCGA
GTATTCAGACTGATTACGTCTCAAGTATTTGGAAAGCTCATCTCTGGAGATGCTGAACCT
ACACCAGAACAAGAGGAAAAAGCACTATTGTCATCACCTGAAGGAGAAGAAAAAGTATAC
AATGCAACATCAGATGCTGACCTGAAAGAACATATGGTTGGAATCATATTCAGCAGGAGT
AAGCTGACTAACTTACAAAAACAGGTGTGTGCTCATATTGTCCAAGCTATTCGCATGGAA
GCTACCAGAGTCCGTGAAGAATGGGAACATGCTATATCAAGCAAAGAAAATGCCAATTCT
CAGCCAAATGATGAAGATGCCTCCTCTGATGCCTACTGCTTTGAGCTGCTCTCTATGGTT
TTAGCACTGAGTGGCTCTAACGTTGGCCGGCAATATCTGGCTCAACAGCTAACCCTGCTT
CAGGATCTCTTCTCGCTGCTTCACACAGCCTCTCCTAGAGTCCAGAGACAGGTAACCTCT
TTACTAAGAAGAGTTTTGCCTGAAGTAACCCCTAGTCGTCTGGCCAGCATCATAGGAGTG
AAATCCCTCCCCCCAGCAGATATCAGTGATATCATTCACTCAACAGAGAAAGGAGACTGG
AATAAGCTGGGTATCTTGGACATGTTTCTAGGATGCATTGCCAAAGCACTCACTGTACAG
CTAAAAGCCAAAGGAACCACCATCACTGGAACAGCTGGTACCACTGTGGGCAAAGGAGTT
ACAACAGTTACTCTTCCGATGATTTTCAATTCCAGTTATCTCCGACGAGGTGAAAGTCAT
TGGTGGATGAAGGGCTCAACCCCTACCCAGATCTCAGAGATCATCATTAAACTTATCAAG
GATATGGCAGCAGGTCATCTGTCAGAAGCTTGGTCCCGAGTGACAAAAAATGCTATTGCA
GAAACCATCATTGCCTTGACCAAGATGGAAGAAGAATTTAGGTCTCCAGTGAGATGTATT
GCAACAACTAGACTCTGGCTTGCTCTCGCATCCCTATGTGTTCTTGATCAGGACCACGTA
GATCGTCTCTCCTCGGGGAGATGGATGGGAAAGGATGGACAACAAAAACAAATGCCTATG
TGTGATAACCATGATGATGGTGAAACTGCAGCAATCATTTTATGCAATGTCTGTGGAAAT
TTATGTACAGACTGTGACAGATTCCTTCACCTTCATCGAAGAACCAAAACTCATCAAAGA
CAGGTCTTCAAAGAAGAAGAAGAAGCTATAAAGGTTGACCTTCATGAAGGTTGTGGTAGA
ACCAAATTGTTCTGGTTGATGGCACTGGCAGATTCTAAAACAATGAAGGCAATGGTGGAA
TTCCGAGAACACACAGGCAAACCCACCACGAGTAGCTCAGAAGCATGTCGCTTCTGTGGT
TCCAGGAGTGGAACAGAGTTATCTGCTGTTGGCAGTGTTTGTTCTGATGCAGATTGCCAG
GAATACGCTAAGATAGCCTGTAGTAAGACGCATCCTTGTGGCCATCCATGCGGGGGTGTT
AAAAACGAAGAGCACTGTCTGCCCTGTCTACACGGCTGTGACAAAAGTGCCACAAGCCTG
AAGCAAGACGCCGATGACATGTGCATGATATGTTTCACCGAAGCGCTCTCGGCAGCACCA
GCCATTCAGCTGGATTGTAGTCACATATTCCACTTACAGTGCTGTCGGCGAGTATTAGAA
AATCGATGGCTTGGCCCAAGGATAACATTTGGATTTATATCTTGTCCCATTTGCAAGAAC
AAAATTAATCACATAGTACTAAAAGACCTACTTGATCCAATAAAAGAACTCTATGAGGAT
GTCAGAAGAAAAGCCTTAATGAGATTGGAATATGAAGGTCTGCATAAGAGTGAAGCTATC
ACAACTCCTGGTGTGAGGTTTTATAATGACCCAGCTGGCTATGCAATGAATAGATATGCA
TATTATGTGTGCTACAAATGCAGAAAGGCATATTTTGGTGGTGAAGCTCGCTGCGATGCT
GAGGCTGGACGGGGAGATGATTATGATCCCAGAGAGCTCATTTGTGGTGCCTGTTCTGAT
GTTTCCAGGGCTCAGATGTGTCCCAAACATGGCACAGACTTTTTGGAATATAAATGTCGC
TACTGCTGTTCAGTGGCTGTTTTTTTCTGTTTTGGAACAACACATTTTTGTAATGCTTGT
CATGATGATTTTCAAAGAATGACTAGCATTCCTAAGGAAGAACTACCACACTGTCCTGCA
GGTCCCAAAGGCAAGCAGTTAGAAGGAACTGAATGTCCACTCCATGTTGTTCATCCACCC
ACTGGGGAAGAGTTTGCTCTGGGATGTGGAGTGTGCAGAAATGCCCACACTTTTTAG
|
| Protein Properties |
|---|
| Number of Residues
| 4640 |
| Molecular Weight
| 510079.5 |
| Theoretical pI
| 7.03 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable E3 ubiquitin-protein ligase MYCBP2
MPVPDGSVAAAGLGLGLPAADSRGHYQLLLSGRALADRYRRIYTAALNDRDQGGGSAGHP
ASRNKKILNKKKLKRKQKSKSKVKTRSKSENLENTVIIPDIKLHSNPSAFNIYCNVRHCV
LEWQKKEISLAAASKNSVQSGESDSDEEEESKEPPIKLPKIIEVGLCEVFELIKETRFSH
PSLCLRSLQALLNVLQGQQPEGLQSEPPEVLESLFQLLLEITVRSTGMNDSTGQSLTALS
CACLFSLVASWGETGRTLQAISAILTNNGSHACQTIQVPTILNSLQRSVQAVLVGKIQIQ
DWFSNGIKKAALMHKWPLKEISVDEDDQCLLQNDGFFLYLLCKDGLYKIGSGYSGTVRGH
IYNSTSRIRNRKEKKSWLGYAQGYLLYRDVNNHSMTAIRISPETLEQDGTVMLPDCHTEG
QNILFTDGEYINQIAASRDDGFVVRIFATSTEPVLQQELQLKLARKCLHACGISLFDLEK
DLHIISTGFDEESAILGAGREFALMKTANGKIYYTGKYQSLGIKQGGPSAGKWVELPITK
SPKIVHFSVGHDGSHALLVAEDGSIFFTGSASKGEDGESTKSRRQSKPYKPKKIIKMEGK
IVVYTACNNGSSSVISKDGELYMFGKDAIYSDSSSLVTDLKGHFVTQVAMGKAHTCVLMK
NGEVWTFGVNNKGQCGRDTGAMNQGGKGFGVENMATAMDEDLEEELDEKDEKSMMCPPGM
HKWKLEQCMVCTVCGDCTGYGASCVSSGRPDRVPGGICGCGSGESGCAVCGCCKACAREL
DGQEARQRGILDAVKEMIPLDLLLAVPVPGVNIEEHLQLRQEEKRQRVIRRHRLEEGRGP
LVFAGPIFMNHREQALARLRSHPAQLKHKRDKHKDGSGERGEKDASKITTYPPGSVRFDC
ELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLGHGDVNSRGCPTLVQALPGPSTQVTA
GSNHTAVLLMDGQVFTFGSFSKGQLGRPILDVPYWNAKPAPMPNIGSKYGRKATWIGASG
DQTFLRIDEALINSHVLATSEIFASKHIIGLVPASISEPPPFKCLLINKVDGSCKTFNDS
EQEDLQGFGVCLDPVYDVIWRFRPNTRELWCYNAVVADARLPSAADMQSRCSILSPELAL
PTGSRALTTRSHAALHILGCLDTLAAMQDLKMGVASTEEETQAVMKVYSKEDYSVVNRFE
SHGGGWGYSAHSVEAIRFSADTDILLGGLGLFGGRGEYTAKIKLFELGPDGGDHETDGDL
LAETDVLAYDCAAREKYAMMFDEPVLLQAGWWYVAWARVSGPSSDCGSHGQASITTDDGV
VFQFKSSKKSNNGTDVNAGQIPQLLYRLPTSDGSASKGKQQTSEPVHILKRSFARTVSVE
CFESLLSILHWSWTTLVLGVEELRGLKGFQFTATLLDLERLRFVGTCCLRLLRVYTCEIY
PVSATGKAVVEETSKLAECIGKTRTLLRKILSEGVDHCMVKLDNDPQGYLSQPLSLLEAV
LQECHNTFTACFHSFYPTPALQWACLCDLLNCLDQDIQEANFKTSSSRLLAAVMSALCHT
SVKLTSIFPIAYDGEVLLRSIVKQVSTENDSTLVHRFPLLVAHMEKLSQSEENISGMTSF
REVLEKMLVIVVLPVRNSLRRENELFSSHLVSNTCGLLASIVSELTASALGSEVDGLNSL
HSVKASANRFTKTSQGRSWNTGNGSPDAICFSVDKPGIVVVGFSVYGGGGIHEYELEVLV
DDSEHAGDSTHSHRWTSLELVKGTYTTDDSPSDIAEIRLDKVVPLKENVKYAVRLRNYGS
RTANGDGGMTTVQCPDGVTFTFSTCSLSSNGTNQTRGQIPQILYYRSEFDGDLQSQLLSK
ANEEDKNCSRALSVVSTVVRASKDLLHRALAVDADDIPELLSSSSLFSMLLPLIIAYIGP
VAAAIPKVAVEVFGLVQQLLPSVAILNQKYAPPAFNPNQSTDSTTGNQPEQGLSACTTSS
HYAVIESEHPYKPACVMHYKVTFPECVRWMTIEFDPQCGTAQSEDVLRLLIPVRTVQNSG
YGPKLTSVHENLNSWIELKKFSGSSGWPTMVLVLPGNEALFSLETASDYVKDDKASFYGF
KCFAIGYEFSPGPDEGVIQLEKELANLGGVCAAALMKKDLALPIGNELEEDLEILEEAAL
QVCKTHSGILGKGLALSHSPTILEALEGNLPLQIQSNEQSFLDDFIACVPGSSGGRLARW
LQPDSYADPQKTSLILNKDDIRCGWPTTITVQTKDQYGDVVHVPNMKVEVKAVPVSQKKM
SLQQDQAKKPQRIPGSPAVTAASSNTDMTYGGLASPKLDVSYEPMIVKEARYIAITMMKV
YENYSFEELRFASPTPKRPSENMLIRVNNDGTYCANWTPGAIGLYTLHVTIDGIEIDAGL
EVKVKDPPKGMIPPGTQLVKPKSEPQPNKVRKFVAKDSAGLRIRSHPSLQSEQIGIVKVN
GTITFIDEIHNDDGVWLRLNDETIKKYVPNMNGYTEAWCLSFNQHLGKSLLVPVDESKTN
TDDFFKDINSCCPQEATMQEQDMPFLRGGPGMYKVVKTGPSGHNIRSCPNLRGIPIGMLV
LGNKVKAVGEVTNSEGTWVQLDQNSMVEFCESDEGEAWSLARDRGGNQYLRHEDEQALLD
QNSQTPPPSPFSVQAFNKGASCSAQGFDYGLGNSKGDRGNISTSSKPASTSGKSELSSKH
SRSLKPDGRMSRTTADQKKPRGTESLSASESLILKSDAAKLRSDSHSRSLSPNHNTLQTL
KSDGRMPSSSRAESPGPGSRLSSPKPKTLPANRSSPSGASSPRSSSPHDKNLPQKSTAPV
KTKLDPPRERSKSDSYTLDPDTLRKKKMPLTEPLRGRSTSPKPKSVPKDSTDSPGSENRA
PSPHVVQENLHSEVVEVCTSSTLKTNSLTDSTCDDSSEFKSVDEGSNKVHFSIGKAPLKD
EQEMRASPKISRKCANRHTRPKKEKSSFLFKGDGSKPLEPAKQAMSPSVAECARAVFASF
LWHEGIVHDAMACSSFLKFHPELSKEHAPIRSSLNSQQPTEEKETKLKNRHSLEISSALN
MFNIAPHGPDISKMGSINKNKVLSMLKEPPLHEKCEDGKTETTFEMSMHNTMKSKSPLPL
TLQHLVAFWEDISLATIKAASQNMIFPSPGSCAVLKKKECEKENKKSKKEKKKKEKAEVR
PRGNLFGEMAQLAVGGPEKDTICELCGESHPYPVTYHMRQAHPGCGRYAGGQGYNSIGHF
CGGWAGNCGDGGIGGSTWYLVCDRCREKYLREKQAAAREKVKQSRRKPMQVKTPRALPTM
EAHQVIKANALFLLSLSSAAEPSILCYHPAKPFQSQLPSVKEGISEDLPVKMPCLYLQTL
ARHHHENFVGYQDDNLFQDEMRYLRSTSVPAPYISVTPDASPNVFEEPESNMKSMPPSLE
TSPITDTDLAKRTVFQRSYSVVASEYDKQHSILPARVKAIPRRRVNSGDTEVGSSLLRHP
SPELSRLISAHSSLSKGERNFQWPVLAFVIQHHDLEGLEIAMKQALRKSACRVFAMEAFN
WLLCNVIQTTSLHDILWHFVASLTPAPVEPEEEEDEENKTSKENSEQEKDTRVCEHPLSD
IVIAGEAAHPLPHTFHRLLQTISDLMMSLPSGSSLQQMALRCWSLKFKQSDHQFLHQSNV
FHHINNILSKSDDGDSEESFSISIQSGFEAMSQELCIVMCLKDLTSIVDIKTSSRPAMIG
SLTDGSTETFWESGDEDKNKTKNITINCVKGINARYVSVHVDNSRDLGNKVTSMTFLTGK
AVEDLCRIKQVDLDSRHIGWVTSELPGGDNHIIKIELKGPENTLRVRQVKVLGWKDGEST
KIAGQISASVAQQRNCEAETLRVFRLITSQVFGKLISGDAEPTPEQEEKALLSSPEGEEK
VYNATSDADLKEHMVGIIFSRSKLTNLQKQVCAHIVQAIRMEATRVREEWEHAISSKENA
NSQPNDEDASSDAYCFELLSMVLALSGSNVGRQYLAQQLTLLQDLFSLLHTASPRVQRQV
TSLLRRVLPEVTPSRLASIIGVKSLPPADISDIIHSTEKGDWNKLGILDMFLGCIAKALT
VQLKAKGTTITGTAGTTVGKGVTTVTLPMIFNSSYLRRGESHWWMKGSTPTQISEIIIKL
IKDMAAGHLSEAWSRVTKNAIAETIIALTKMEEEFRSPVRCIATTRLWLALASLCVLDQD
HVDRLSSGRWMGKDGQQKQMPMCDNHDDGETAAIILCNVCGNLCTDCDRFLHLHRRTKTH
QRQVFKEEEEAIKVDLHEGCGRTKLFWLMALADSKTMKAMVEFREHTGKPTTSSSEACRF
CGSRSGTELSAVGSVCSDADCQEYAKIACSKTHPCGHPCGGVKNEEHCLPCLHGCDKSAT
SLKQDADDMCMICFTEALSAAPAIQLDCSHIFHLQCCRRVLENRWLGPRITFGFISCPIC
KNKINHIVLKDLLDPIKELYEDVRRKALMRLEYEGLHKSEAITTPGVRFYNDPAGYAMNR
YAYYVCYKCRKAYFGGEARCDAEAGRGDDYDPRELICGACSDVSRAQMCPKHGTDFLEYK
CRYCCSVAVFFCFGTTHFCNACHDDFQRMTSIPKEELPHCPAGPKGKQLEGTECPLHVVH
PPTGEEFALGCGVCRNAHTF
|
| External Links |
|---|
| GenBank ID Protein
| 291190787 |
| UniProtKB/Swiss-Prot ID
| O75592 |
| UniProtKB/Swiss-Prot Entry Name
| MYCB2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_015057 |
| GeneCard ID
| MYCBP2 |
| GenAtlas ID
| MYCBP2 |
| HGNC ID
| HGNC:23386 |
| References |
|---|
| General References
| Not Available |