| Identification |
|---|
| HMDB Protein ID
| CDBP04400 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ubiquitin-conjugating enzyme E2 U |
| Description
| Not Available |
| Synonyms
|
- Ubiquitin carrier protein U
- Ubiquitin-protein ligase U
|
| Gene Name
| UBE2U |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in acid-amino acid ligase activity |
| Specific Function
| Catalyzes the covalent attachment of ubiquitin to other proteins (By similarity).
|
| GO Classification
|
| Function |
| ligase activity |
| ligase activity, forming carbon-nitrogen bonds |
| acid-amino acid ligase activity |
| catalytic activity |
| small conjugating protein ligase activity |
| Molecular Function |
| ubiquitin-protein ligase activity |
| ATP binding |
| Process |
| metabolic process |
| regulation of protein metabolic process |
| macromolecule metabolic process |
| biological regulation |
| regulation of biological process |
| regulation of metabolic process |
| regulation of macromolecule metabolic process |
| post-translational protein modification |
| macromolecule modification |
| protein modification process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | protein ubiquitination | Not Available | Not Available | | Ubiquitin mediated proteolysis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1p31.3 |
| SNPs
| UBE2U |
| Gene Sequence
|
>966 bp
ATGCACGGCAGAGCTTACCTCTTGCTGCACAGAGACTTCTGTGATCTCAAGGAGAACAAT
TATAAGGGTATCACTGCTAAGCCTGTAAGTGAAGATATGATGGAATGGGAAGTTGAAATT
GAAGGTCTACAGAATTCAGTTTGGCAGGGTTTAGTCTTCCAACTGACAATACATTTTACA
TCGGAGTACAACTATGCTCCTCCAGTTGTGAAATTTATAACAATTCCGTTTCATCCAAAT
GTAGACCCACACACTGGTCAGCCCTGTATAGACTTTTTGGACAACCCTGAGAAGTGGAAT
ACAAACTATACATTGAGCAGCATCTTACTTGCCCTACAGGTTATGCTTTCTAATCCAGTG
CTAGAGAATCCAGTGAATTTGGAAGCAGCCAGAATACTGGTTAAAGATGAATCTCTGTAC
AGAACAATTCTAAGACTTTTCAACAGGCCATTACAAATGAAAGATGACAGCCAGGAGTTA
CCTAAAGACCCACGTAAATGTATCAGACCAATTAAAACAACCTCATTTAGTGATTACTAC
CAGACATGGTCCAGAATAGCTACATCAAAAGCCACAGAATACTACAGAACTCCATTGCTC
AAAGTTCCAAATTTCATTGGACAGTATTACAAATGGAAGAAAATGGATCTACAGCATCAG
AAAGAATGGAATTTAAAGTATTCCGTTATCAAGTGTTGGCTTGCTAGAAAAAGAATGCCT
CATGAAGTCACTCACTCAATGGAAGAAATTAAGCTCTGCCCAACTCTAATTCCCACCACA
GATGAAATTTTTCTTGAGTCACCAACTGCAATAAATAGCATCACAGACATTTATGAAACA
GAAGAGGAGGGGTGGAAGAGTGACACTTCATTATATGAAAATGACACAGATGAGCCCAGG
GAAGAGGAAGTGGAAGATCTGATCTCCTGGACCAATACTCTCAATACAAATACTTCAGAA
GATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 321 |
| Molecular Weight
| 26688.485 |
| Theoretical pI
| 7.887 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ubiquitin-conjugating enzyme E2 U
MHGRAYLLLHRDFCDLKENNYKGITAKPVSEDMMEWEVEIEGLQNSVWQGLVFQLTIHFT
SEYNYAPPVVKFITIPFHPNVDPHTGQPCIDFLDNPEKWNTNYTLSSILLALQVMLSNPV
LENPVNLEAARILVKDESLYRTILRLFNRPLQMKDDSQELPKDPRKCIRPIKTTSFSDYY
QTWSRIATSKATEYYRTPLLKVPNFIGQYYKWKKMDLQHQKEWNLKYSVIKCWLARKRMP
HEVTHSMEEIKLCPTLIPTTDEIFLESPTAINSITDIYETEEEGWKSDTSLYENDTDEPR
EEEVEDLISWTNTLNTNTSED
|
| External Links |
|---|
| GenBank ID Protein
| 56205233 |
| UniProtKB/Swiss-Prot ID
| Q5VVX9 |
| UniProtKB/Swiss-Prot Entry Name
| UBE2U_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL161916 |
| GeneCard ID
| UBE2U |
| GenAtlas ID
| UBE2U |
| HGNC ID
| HGNC:28559 |
| References |
|---|
| General References
| Not Available |