| Identification |
|---|
| HMDB Protein ID
| CDBP04383 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable threonine--tRNA ligase 2, cytoplasmic |
| Description
| Not Available |
| Synonyms
|
- ThrRS
- Threonine--tRNA ligase
- Threonyl-tRNA synthetase-like protein 2
- Threonyl-tRNA synthetase
|
| Gene Name
| TARSL2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in nucleotide binding |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| threonyl-tRNA aminoacylation |
| Cellular Component |
| cytoplasm |
| Component |
| cell part |
| intracellular part |
| cytoplasm |
| Function |
| ligase activity, forming carbon-oxygen bonds |
| ligase activity, forming aminoacyl-trna and related compounds |
| aminoacyl-trna ligase activity |
| binding |
| nucleotide binding |
| catalytic activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| ligase activity |
| threonine-trna ligase activity |
| Molecular Function |
| ATP binding |
| threonine-tRNA ligase activity |
| Process |
| threonyl-trna aminoacylation |
| biosynthetic process |
| rna metabolic process |
| ncrna metabolic process |
| trna metabolic process |
| trna aminoacylation |
| trna aminoacylation for protein translation |
| macromolecule biosynthetic process |
| cellular macromolecule biosynthetic process |
| translation |
| metabolic process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Aminoacyl-tRNA biosynthesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 15 |
| Locus
| 15q26.3 |
| SNPs
| TARSL2 |
| Gene Sequence
|
>2409 bp
ATGGCGGCCGAGGCCCTGGCGGCGGAGGCCGTGGCGTCGCGCCTGGAGCGGCAGGAGGAG
GACATCCGCTGGCTGTGGTCGGAGGTCGAGCGCCTGAGGGACGAGCAGCTGAACGCGCCC
TACAGCTGCCAGGCGGAGGGGCCGTGCCTCACGCGGGAGGTGGCGCAGCTCCGGGCCGAG
AACTGCGACCTGCGCCACCGCCTGTGCAGCCTGCGGCTGTGCCTCGCCGAGGAGCGGAGC
CGCCAGGCCACGCTGGAGAGCGCGGAGCTAGAGGCGGCGCAGGAGGCCGGCGCACAGCCT
CCTCCTAGTCAAAGCCAAGACAAGGACATGAAAAAGAAGAAAATGAAGGAAAGCGAGGCT
GACAGCGAGGTGAAGCATCAACCAATTTTCATAAAAGAAAGATTGAAGCTTTTTGAAATA
CTGAAGAAAGACCATCAGCTCTTACTTGCCATTTATGGAAAAAAGGGGGATACAAGCAAC
ATCATCACAGTAAGAGTGGCTGATGGGCAAACAGTGCAAGGGGAAGTCTGGAAAACAACG
CCTTACCAAGTGGCTGCTGAAATTAGTCAGGAACTGGCTGAAAGCACGGTAATAGCCAAA
GTCAATGGTGAACTGTGGGACCTGGACCGCCCATTGGAAGGGGACTCTTCTCTAGAGCTG
CTTACATTTGATAATGAGGAAGCTCAAGCTGTGTACTGGCACTCCAGTGCTCACATTCTT
GGGGAGGCCATGGAGCTTTACTATGGAGGCCACCTGTGCTACGGTCCGCCCATTGAAAAT
GGATTTTATTATGACATGTTCATTGAAGACAGAGCAGTGTCCAGCACAGAATTGTCAGCC
CTGGAGAATATATGTAAAGCCATCATAAAAGAAAAGCAACCTTTTGAAAGACTAGAAGTC
AGCAAGGAAATCCTCCTGGAAATGTTTAAGTACAATAAATTTAAATGCCGCATTCTGAAT
GAGAAAGTTAACACTGCAACTACCACCGTGTACAGGTGCGGTCCATTAATTGACCTTTGC
AAAGGTCCACATGTAAGACACACTGGAAAAATTAAAACCATCAAAATTTTTAAGAATTCC
TCAACATATTGGGAGGGCAATCCGGAAATGGAAACATTGCAGAGGATCTATGGAATATCC
TTTCCTGATAACAAGATGATGAGAGACTGGGAAAAGTTCCAAGAGGAAGCAAAGAACCGA
GATCACAGGAAGATCGGGAAGGAACAAGAACTTTTCTTTTTCCACGATTTGAGTCCTGGA
AGCTGTTTTTTCCTTCCCAGAGGAGCCTTCATTTATAATACGCTTACAGATTTCATACGA
GAGGAATATCACAAACGGGACTTCACGGAGGTGCTCTCTCCCAATATGTACAACAGTAAA
CTCTGGGAAGCCTCAGGCCACTGGCAGCATTACAGCGAGAACATGTTTACCTTTGAGATT
GAAAAGGACACTTTTGCCCTCAAACCCATGAATTGTCCAGGGCACTGTCTAATGTTTGCC
CATCGTCCACGATCTTGGAGGGAAATGCCTATTAGATTTGCTGATTTTGGAGTTCTGCAT
AGAAATGAACTGTCGGGGACTCTCAGCGGCTTGACCAGAGTGAGGCGCTTCCAGCAGGAC
GATGCTCACATTTTTTGCACAGTGGAGCAGATTGAAGAAGAAATAAAGGGGTGTTTGCAG
TTTTTGCAATCTGTTTACTCAACATTTGGCTTCTCCTTTCAATTAAACCTGTCAACAAGG
CCGGAAAACTTCCTAGGAGAGATTGAGATGTGGAATGAGGCTGAGAAGCAACTGCAGAAC
AGCTTGATGGACTTTGGAGAACCGTGGAAAATGAACCCAGGAGATGGAGCATTTTATGGC
CCTAAAATTGACATAAAAATCAAGGATGCTATTGGCAGATACCATCAATGTGCTACAATT
CAGCTGGACTTCCAACTGCCTATTAGATTTAATCTCACATATGTTAGTAAGGATGGGGAT
GATAAGAAGAGACCTGTGATCATTCATCGAGCCATTTTGGGATCAGTGGAAAGAATGATA
GCCATTCTTTCAGAAAACTATGGCGGAAAATGGCCTTTCTGGCTATCTCCTCGTCAGGTG
ATGGTCATCCCTGTGGGGCCAACTTGTGAAAAATATGCACTTCAGGTATCCAGTGAATTT
TTTGAAGAAGGATTTATGGCTGACGTTGACTTGGATCACAGTTGTACACTAAATAAGAAA
ATACGAAATGCACAGCTGGCTCAGTATAATTTTATTTTGGTGGTTGGAGAAAAGGAAAAG
ATAGATAATGCTGTAAACGTGCGAACAAGAGACAACAAAATTCATGGAGAGATTTTAGTA
ACTTCTGCCATTGATAAACTGAAGAATCTCAGGAAGACACGGACACTCAATGCTGAGGAG
GCCTTTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 802 |
| Molecular Weight
| 92644.755 |
| Theoretical pI
| 6.054 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Probable threonyl-tRNA synthetase 2, cytoplasmic
MAAEALAAEAVASRLERQEEDIRWLWSEVERLRDEQLNAPYSCQAEGPCLTREVAQLRAE
NCDLRHRLCSLRLCLAEERSRQATLESAELEAAQEAGAQPPPSQSQDKDMKKKKMKESEA
DSEVKHQPIFIKERLKLFEILKKDHQLLLAIYGKKGDTSNIITVRVADGQTVQGEVWKTT
PYQVAAEISQELAESTVIAKVNGELWDLDRPLEGDSSLELLTFDNEEAQAVYWHSSAHIL
GEAMELYYGGHLCYGPPIENGFYYDMFIEDRAVSSTELSALENICKAIIKEKQPFERLEV
SKEILLEMFKYNKFKCRILNEKVNTATTTVYRCGPLIDLCKGPHVRHTGKIKTIKIFKNS
STYWEGNPEMETLQRIYGISFPDNKMMRDWEKFQEEAKNRDHRKIGKEQELFFFHDLSPG
SCFFLPRGAFIYNTLTDFIREEYHKRDFTEVLSPNMYNSKLWEASGHWQHYSENMFTFEI
EKDTFALKPMNCPGHCLMFAHRPRSWREMPIRFADFGVLHRNELSGTLSGLTRVRRFQQD
DAHIFCTVEQIEEEIKGCLQFLQSVYSTFGFSFQLNLSTRPENFLGEIEMWNEAEKQLQN
SLMDFGEPWKMNPGDGAFYGPKIDIKIKDAIGRYHQCATIQLDFQLPIRFNLTYVSKDGD
DKKRPVIIHRAILGSVERMIAILSENYGGKWPFWLSPRQVMVIPVGPTCEKYALQVSSEF
FEEGFMADVDLDHSCTLNKKIRNAQLAQYNFILVVGEKEKIDNAVNVRTRDNKIHGEILV
TSAIDKLKNLRKTRTLNAEEAF
|
| External Links |
|---|
| GenBank ID Protein
| 38570111 |
| UniProtKB/Swiss-Prot ID
| A2RTX5 |
| UniProtKB/Swiss-Prot Entry Name
| SYTC2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_152334.2 |
| GeneCard ID
| TARSL2 |
| GenAtlas ID
| TARSL2 |
| HGNC ID
| HGNC:24728 |
| References |
|---|
| General References
| Not Available |