Identification |
HMDB Protein ID
| CDBP04369 |
Secondary Accession Numbers
| Not Available |
Name
| Very-long-chain enoyl-CoA reductase |
Description
| Not Available |
Synonyms
|
- Synaptic glycoprotein SC2
- TER
- Trans-2,3-enoyl-CoA reductase
|
Gene Name
| TECR |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in oxidoreductase activity, acting on the CH-CH group of donors |
Specific Function
| Reduces trans-2,3-stearoyl-CoA to stearoyl-CoA of long and very long chain fatty acids.
|
GO Classification
|
Biological Process |
very long-chain fatty acid biosynthetic process |
long-chain fatty-acyl-CoA biosynthetic process |
triglyceride biosynthetic process |
fatty acid elongation |
Cellular Component |
integral to endoplasmic reticulum membrane |
Component |
cell part |
intracellular part |
cytoplasm |
membrane part |
intrinsic to membrane |
integral to membrane |
Function |
oxidoreductase activity, acting on the ch-ch group of donors |
catalytic activity |
oxidoreductase activity |
Molecular Function |
oxidoreductase activity, acting on the CH-CH group of donors |
Process |
metabolic process |
primary metabolic process |
lipid metabolic process |
|
Cellular Location
|
- Endoplasmic reticulum membrane
- Multi-pass membrane protein
|
Pathways
|
Name | SMPDB/Pathwhiz | KEGG | Fatty acid elongation | Not Available | | Biosynthesis of unsaturated fatty acids | Not Available | |
|
Gene Properties |
Chromosome Location
| 19 |
Locus
| 19p13.12 |
SNPs
| TECR |
Gene Sequence
|
>927 bp
ATGAAGCATTACGAGGTGGAGATTCTGGACGCAAAGACAAGGGAGAAGCTGTGTTTCTTG
GACAAGGTGGAGCCCCACGCCACCATTGCGGAGATCAAGAACCTCTTCACTAAGACCCAT
CCGCAGTGGTACCCCGCCCGCCAGTCCCTCCGCCTGGACCCCAAGGGCAAGTCCCTGAAG
GATGAGGATGTTCTGCAGAAGCTGCCCGTGGGACCACGCGCACACCTGTACTTCCGGGAC
CTGGGGGCCCAGATCAGCTGGGTGACGGTCTTCCTAACAGAGTACGCGGGGCCCCTTTTC
ATCTACCTGCTCTTCTACTTCCGAGTGCCCTTCATCTATGGCCACAAATATGACTTTACG
TCCAGTCGGCATACAGTGGTGCACCTCGCCTGCATCTGTCACTCATTCCACTACATCAAG
CGCCTGCTGGAGACGCTCTTCGTGCACCGCTTCTCCCATGGCACTATGCCTTTGCGCAAC
ATCTTTAAGAACTGCACCTACTACTGGGGCTTCGCCGCGTGGATGGCCTATTACATCAAT
CACCCTCTCTACACTCCCCCTACCTACGGAGCTCAGCAGGTGAAACTGGCGCTCGCCATC
TTTGTGATCTGCCAGCTCGGCAACTTCTCCATCCACATGGCCCTGCGGGACCTGCGGCCC
GCTGGGTCCAAGACGCGGAAGATCCCATACCCCACCAAGAACCCCTTCACGTGGCTCTTC
CTGCTGGTGTCCTGCCCCAACTGCACCTACGAGGTGGGGTCCTGGATCGGTTTCGCCATC
ATGACGCAGTGTCTCCCAGTGGCCCTGTTCTCCCTGGTGGGCTTCACCCAGATGACCATC
TGGGCCAAGGGCAAGCACCGCAGCTACCTGAAGGAGTTCCGGGACTACCCGCCCCTGCGC
ATGCCCATCATCCCCTTCCTGCTCTGA
|
Protein Properties |
Number of Residues
| 308 |
Molecular Weight
| 36034.065 |
Theoretical pI
| 9.445 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Trans-2,3-enoyl-CoA reductase
MKHYEVEILDAKTREKLCFLDKVEPHATIAEIKNLFTKTHPQWYPARQSLRLDPKGKSLK
DEDVLQKLPVGTTATLYFRDLGAQISWVTVFLTEYAGPLFIYLLFYFRVPFIYGHKYDFT
SSRHTVVHLACICHSFHYIKRLLETLFVHRFSHGTMPLRNIFKNCTYYWGFAAWMAYYIN
HPLYTPPTYGAQQVKLALAIFVICQLGNFSIHMALRDLRPAGSKTRKIPYPTKNPFTWLF
LLVSCPNYTYEVGSWIGFAIMTQCLPVALFSLVGFTQMTIWAKGKHRSYLKEFRDYPPLR
MPIIPFLL
|
External Links |
GenBank ID Protein
| 3329386 |
UniProtKB/Swiss-Prot ID
| Q9NZ01 |
UniProtKB/Swiss-Prot Entry Name
| TECR_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| AF038958 |
GeneCard ID
| TECR |
GenAtlas ID
| TECR |
HGNC ID
| HGNC:4551 |
References |
General References
| Not Available |