| Identification |
|---|
| HMDB Protein ID
| CDBP04354 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable tRNA pseudouridine synthase 2 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| TRUB2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in RNA processing |
| Specific Function
| May be responsible for synthesis of pseudouridine from uracil in transfer RNAs |
| GO Classification
|
| Function |
| binding |
| catalytic activity |
| nucleic acid binding |
| isomerase activity |
| pseudouridine synthase activity |
| intramolecular transferase activity |
| rna binding |
| Process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
| rna processing |
| rna modification |
| pseudouridine synthesis |
| rna metabolic process |
| metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:9 |
| Locus
| 9q34.11 |
| SNPs
| TRUB2 |
| Gene Sequence
|
>996 bp
ATGGGGTCTGCTGGCTTGTCGCGGCTGCATGGGCTTTTCGCGGTCTATAAGCCCCCGGGG
CTAAAATGGAAGCACCTGCGGGATACAGTGGAGCTACAACTTCTGAAGGGTCTCAATGCC
AGGAAGCCTCCCGCTCCTAAACAGCGTGTTCGCTTCTTGCTGGGCCCCATGGAAGGCAGC
GAAGAGAAGGAGCTGACCCTCACAGCCACCAGCGTACCCTCTTTCATCAACCATCCACTG
GTATGTGGACCAGCATTCGCCCATCTCAAGGTTGGCGTGGGACATCGGTTGGATGCCCAG
GCTTCTGGAGTACTTGTGCTCGGCGTGGGACATGGATGCAGGCTCCTCACCGATATGTAC
AATGCTCATCTTACCAAGGATTACACAGTGCGTGGCCTCCTGGGCAAAGCTACAGATGAC
TTCCGTGAGGACGGGAGGCTGGTAGAGAAGACAACCTATGACCACGTGACCAGAGAGAAG
CTGGACCGCATTCTGGCCGTTATCCAAGGCTCCCATCAGAAGGCCCTGGTGATGTACTCC
AACCTCGACCTGAAGACCCAGGAGGCCTATGAGATGGCCGTGAGAGGCCTGATCCGGCCC
ATGAACAAGTCCCCGATGCTGATAACTGGCATCCGATGCCTCTACTTTGCACCTCCGGAA
TTCCTCTTAGAGGTGCAGTGCATGCATGAGACGCAGAAAGAGCTGCGGAAGTTGGTTCAT
GAAATCGGCCTGGAACTAAAGACCACTGCTGTCTGCACCCAAGTGCGGCGCACGCGCGAC
GGCTTCTTCACGCTAGACAGTGCCCTCCTGAGGACCCAGTGGGACCTAACCAACATCCAG
GATGCTATCCGGGCTGCTACCCCTCAGGTAGCTGCAGAGCTGGAGAAGAGCTTGAGCCCG
GGGCTGGACACCAAGCAGCTCCCCAGTCCGGGATGGTCCTGGGACTCCCAGGGCCCGAGC
TCTACCTTGGGGCTGGAGAGGGGTGCGGGGCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 331 |
| Molecular Weight
| 36694.1 |
| Theoretical pI
| 9.36 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable tRNA pseudouridine synthase 2
MGSAGLSRLHGLFAVYKPPGLKWKHLRDTVELQLLKGLNARKPPAPKQRVRFLLGPMEGS
EEKELTLTATSVPSFINHPLVCGPAFAHLKVGVGHRLDAQASGVLVLGVGHGCRLLTDMY
NAHLTKDYTVRGLLGKATDDFREDGRLVEKTTYDHVTREKLDRILAVIQGSHQKALVMYS
NLDLKTQEAYEMAVRGLIRPMNKSPMLITGIRCLYFAPPEFLLEVQCMHETQKELRKLVH
EIGLELKTTAVCTQVRRTRDGFFTLDSALLRTQWDLTNIQDAIRAATPQVAAELEKSLSP
GLDTKQLPSPGWSWDSQGPSSTLGLERGAGQ
|
| External Links |
|---|
| GenBank ID Protein
| 4406691 |
| UniProtKB/Swiss-Prot ID
| O95900 |
| UniProtKB/Swiss-Prot Entry Name
| TRUB2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF131848 |
| GeneCard ID
| TRUB2 |
| GenAtlas ID
| TRUB2 |
| HGNC ID
| HGNC:17170 |
| References |
|---|
| General References
| Not Available |