| Identification |
|---|
| HMDB Protein ID
| CDBP04353 |
| Secondary Accession Numbers
| Not Available |
| Name
| Probable tRNA pseudouridine synthase 1 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| TRUB1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in RNA processing |
| Specific Function
| May be responsible for synthesis of pseudouridine from uracil in transfer RNAs |
| GO Classification
|
| Function |
| nucleic acid binding |
| isomerase activity |
| pseudouridine synthase activity |
| intramolecular transferase activity |
| rna binding |
| binding |
| catalytic activity |
| Process |
| rna metabolic process |
| metabolic process |
| macromolecule metabolic process |
| cellular macromolecule metabolic process |
| rna processing |
| rna modification |
| pseudouridine synthesis |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 10q25.3 |
| SNPs
| TRUB1 |
| Gene Sequence
|
>1050 bp
ATGGCCGCTTCTGAGGCGGCGGTGGTGTCTTCGCCGTCTTTGAAAACAGACACATCCCCT
GTCCTTGAAACTGCAGGAACGGTCGCAGCAATGGCTGCGACCCCGTCAGCAAGGGCTGCA
GCCGCGGTGGTTGCGGCCGCGGCCAGGACCGGATCCGAAGCCAGGGTCTCCAAGGCCGCT
TTGGCTACCAAGCTGCTGTCCTTGAGCGGCGTGTTCGCCGTGCACAAGCCCAAAGGGCCC
ACTTCAGCCGAGCTGCTGAATCGGTTGAAGGAGAAGCTGCTGGCAGAAGCTGGAATGCCT
TCTCCAGAATGGACCAAGAGGAAAAAGCAGACTTTGAAAATTGGGCATGGAGGGACTCTA
GACAGCGCAGCCCGAGGAGTTCTGGTTGTTGGAATTGGAAGCGGAACAAAAATGTTGACC
AGTATGTTGTCAGGGTCCAAGAGATATACTGCCATTGGAGAACTGGGGAAAGCTACTGAT
ACACTAGATTCTACGGGGAGGGTAACAGAAGAAAAACCTTACGATAAAATAACACAAGAA
GATATTGAAGGCATTCTACAGAAATTTACTGGAAATATAATGCAAGTGCCCCCCCTCTAT
TCTGCATTAAAGAAAGATGGACAAAGACTTTCGACTTTGATGAAGAGAGGTGAAGTCGTA
GAAGCAAAACCTGCCAGGCCAGTGACTGTATACAGTATCTCCCTTCAAAAATTCCAGCCA
CCATTTTTCACATTAGATGTTGAATGTGGAGGAGGTTTTTATATCAGAAGCTTGGTCAGT
GACATTGGAAAAGAACTATCTTCCTGTGCCAATGTGCTAGAGCTGACCCGAACCAAACAG
GGACCATTTACGCTAGAAGAACATGCCCTTCCTGAAGACAAATGGACAATTGATGACATT
GCACAGTCTCTTGAGCATTGCTCATCTCTTTTCCCAGCAGAGTTGGCACTTAAAAAATCA
AAACCTGAGTCTAATGAACAGGTTTTGAGCTGTGAATATATAACTCTAAATGAGCCAAAG
AGAGAAGATGATGTAATTAAGACGTGTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 349 |
| Molecular Weight
| 37252.4 |
| Theoretical pI
| 8.45 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Probable tRNA pseudouridine synthase 1
MAASEAAVVSSPSLKTDTSPVLETAGTVAAMAATPSARAAAAVVAAAARTGSEARVSKAA
LATKLLSLSGVFAVHKPKGPTSAELLNRLKEKLLAEAGMPSPEWTKRKKQTLKIGHGGTL
DSAARGVLVVGIGSGTKMLTSMLSGSKRYTAIGELGKATDTLDSTGRVTEEKPYDKITQE
DIEGILQKFTGNIMQVPPLYSALKKDGQRLSTLMKRGEVVEAKPARPVTVYSISLQKFQP
PFFTLDVECGGGFYIRSLVSDIGKELSSCANVLELTRTKQGPFTLEEHALPEDKWTIDDI
AQSLEHCSSLFPAELALKKSKPESNEQVLSCEYITLNEPKREDDVIKTC
|
| External Links |
|---|
| GenBank ID Protein
| 17484109 |
| UniProtKB/Swiss-Prot ID
| Q8WWH5 |
| UniProtKB/Swiss-Prot Entry Name
| TRUB1_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF448144 |
| GeneCard ID
| TRUB1 |
| GenAtlas ID
| TRUB1 |
| HGNC ID
| HGNC:16060 |
| References |
|---|
| General References
| Not Available |