Identification
HMDB Protein ID CDBP04347
Secondary Accession Numbers Not Available
Name Pseudouridylate synthase 7 homolog
Description Not Available
Synonyms Not Available
Gene Name PUS7
Protein Type Enzyme
Biological Properties
General Function Involved in RNA binding
Specific Function tRNA uridine = tRNA pseudouridine
GO Classification
Function
nucleic acid binding
isomerase activity
pseudouridine synthase activity
intramolecular transferase activity
rna binding
binding
catalytic activity
Process
rna metabolic process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
rna modification
pseudouridine synthesis
Cellular Location
  1. Cytoplasmic
Pathways
Gene Properties
Chromosome Location Chromosome:7
Locus 7q22.3
SNPs PUS7
Gene Sequence
>1986 bp
ATGGAGATGACAGAAATGACTGGTGTGTCGCTGAAACGTGGGGCACTGGTTGTCGAAGAT
AATGACAGTGGAGTCCCAGTTGAAGAGACAAAAAAACAGAAGCTGTCGGAATGCAGTCTA
ACCAAAGGTCAAGATGGGCTACAGAATGACTTTCTGTCCATCAGTGAAGACGTGCCTCGG
CCTCCTGACACTGTCAGTACTGGGAAAGGTGGAAAGAATTCTGAGGCTCAGTTGGAAGAT
GAGGAAGAAGAGGAGGAAGATGGACTTTCAGAGGAGTGCGAGGAGGAGGAATCAGAGAGT
TTTGCAGACATGATGAAGCATGGACTCACTGAGGCTGACGTAGGCATCACCAAGTTTGTG
AGTTCTCATCAAGGGTTCTCGGGAATCTTAAAAGAAAGATACTCCGACTTCGTTGTTCAT
GAAATAGGAAAAGATGGACGGATCAGCCATTTGAATGACTTGTCCATTCCAGTGGATGAG
GAGGACCCTTCAGAAGACATATTTACAGTTTTGACAGCTGAAGAAAAGCAGCGATTGGAA
GAGCTCCAGCTGTTCAAAAATAAGGAAACCAGTGTTGCCATTGAGGTTATCGAGGACACC
AAAGAGAAAAGAACCATCATCCATCAGGCTATCAAATCTCTGTTTCCAGGATTAGAGACA
AAAACAGAGGATAGGGAGGGGAAGAAATACATTGTAGCCTACCACGCAGCTGGGAAAAAG
GCTTTGGCAAATCCAAGAAAACATTCTTGGCCAAAATCTAGGGGAAGTTACTGCCACTTC
GTACTATATAAGGAAAACAAAGACACCATGGATGCTATTAATGTACTCTCCAAATACTTA
AGAGTCAAGCCAAATATATTCTCCTACATGGGAACCAAAGATAAAAGGGCTATAACAGTT
CAAGAAATTGCTGTTCTCAAAATAACTGCACAAAGACTTGCCCACCTGAATAAGTGCTTG
ATGAACTTTAAGCTAGGGAATTTCAGCTATCAAAAAAACCCACTGAAATTGGGAGAGCTT
CAAGGAAACCACTTCACTGTTGTTCTCAGAAATATAACAGGAACTGATGACCAAGTACAG
CAAGCTATGAACTCTCTCAAGGAGATTGGATTTATTAACTACTATGGAATGCAAAGATTT
GGAACCACAGCTGTCCCTACGTATCAGGTTGGAAGAGCTATACTACAAAATTCCTGGACA
GAAGTCATGGATTTAATATTGAAACCCCGCTCTGGAGCTGAAAAGGGCTACTTGGTTAAA
TGCAGAGAAGAATGGGCAAAGACCAAAGACCCAACTGCTGCCCTCAGAAAACTACCTGTC
AAAAGGTGTGTGGAAGGGCAGCTGCTTCGAGGACTTTCAAAATATGGAATGAAGAATATA
GTCTCTGCATTTGGCATAATACCCAGAAATAATCGCTTAATGTATATTCATAGCTACCAA
AGCTATGTGTGGAATAACATGGTAAGCAAGAGGATAGAAGACTATGGACTAAAACCTGTT
CCAGGGGACCTCGTTCTCAAAGGAGCCACAGCCACCTATATTGAGGAAGATGATGTTAAT
AATTACTCTATCCATGATGTGGTAATGCCCTTGCCTGGTTTCGATGTTATCTACCCAAAG
CATAAAATTCAAGAAGCCTACAGGGAAATGCTCACAGCTGACAATCTTGATATTGACAAC
ATGAGACACAAAATTCGAGATTATTCCTTGTCAGGGGCCTACCGAAAGATCATTATTCGT
CCTCAGAATGTTAGCTGGGAAGTCGTTGCATATGATGATCCCAAAATTCCACTTTTCAAC
ACAGATGTGGACAACCTAGAAGGGAAGACACCACCAGTTTTTGCTTCTGAAGGCAAATAC
AGGGCTCTGAAAATGGATTTTTCTCTACCCCCTTCTACTTACGCCACCATGGCCATTCGA
GAAGTGCTAAAAATGGATACCAGTATCAAGAACCAGACGCAGCTGAATACAACCTGGCTT
CGCTGA
Protein Properties
Number of Residues 661
Molecular Weight 75034.9
Theoretical pI 6.31
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Pseudouridylate synthase 7 homolog
MEMTEMTGVSLKRGALVVEDNDSGVPVEETKKQKLSECSLTKGQDGLQNDFLSISEDVPR
PPDTVSTGKGGKNSEAQLEDEEEEEEDGLSEECEEEESESFADMMKHGLTEADVGITKFV
SSHQGFSGILKERYSDFVVHEIGKDGRISHLNDLSIPVDEEDPSEDIFTVLTAEEKQRLE
ELQLFKNKETSVAIEVIEDTKEKRTIIHQAIKSLFPGLETKTEDREGKKYIVAYHAAGKK
ALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITV
QEIAVLKITAQRLAHLNKCLMNFKLGNFSYQKNPLKLGELQGNHFTVVLRNITGTDDQVQ
QAMNSLKEIGFINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVK
CREEWAKTKDPTAALRKLPVKRCVEGQLLRGLSKYGMKNIVSAFGIIPRNNRLMYIHSYQ
SYVWNNMVSKRIEDYGLKPVPGDLVLKGATATYIEEDDVNNYSIHDVVMPLPGFDVIYPK
HKIQEAYREMLTADNLDIDNMRHKIRDYSLSGAYRKIIIRPQNVSWEVVAYDDPKIPLFN
TDVDNLEGKTPPVFASEGKYRALKMDFSLPPSTYATMAIREVLKMDTSIKNQTQLNTTWL
R
GenBank ID Protein 50727002
UniProtKB/Swiss-Prot ID Q96PZ0
UniProtKB/Swiss-Prot Entry Name PUS7_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_019042.3
GeneCard ID PUS7
GenAtlas ID PUS7
HGNC ID HGNC:26033
References
General References Not Available