Identification |
HMDB Protein ID
| CDBP04347 |
Secondary Accession Numbers
| Not Available |
Name
| Pseudouridylate synthase 7 homolog |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| PUS7 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in RNA binding |
Specific Function
| tRNA uridine = tRNA pseudouridine |
GO Classification
|
Function |
nucleic acid binding |
isomerase activity |
pseudouridine synthase activity |
intramolecular transferase activity |
rna binding |
binding |
catalytic activity |
Process |
rna metabolic process |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
rna modification |
pseudouridine synthesis |
|
Cellular Location
|
- Cytoplasmic
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:7 |
Locus
| 7q22.3 |
SNPs
| PUS7 |
Gene Sequence
|
>1986 bp
ATGGAGATGACAGAAATGACTGGTGTGTCGCTGAAACGTGGGGCACTGGTTGTCGAAGAT
AATGACAGTGGAGTCCCAGTTGAAGAGACAAAAAAACAGAAGCTGTCGGAATGCAGTCTA
ACCAAAGGTCAAGATGGGCTACAGAATGACTTTCTGTCCATCAGTGAAGACGTGCCTCGG
CCTCCTGACACTGTCAGTACTGGGAAAGGTGGAAAGAATTCTGAGGCTCAGTTGGAAGAT
GAGGAAGAAGAGGAGGAAGATGGACTTTCAGAGGAGTGCGAGGAGGAGGAATCAGAGAGT
TTTGCAGACATGATGAAGCATGGACTCACTGAGGCTGACGTAGGCATCACCAAGTTTGTG
AGTTCTCATCAAGGGTTCTCGGGAATCTTAAAAGAAAGATACTCCGACTTCGTTGTTCAT
GAAATAGGAAAAGATGGACGGATCAGCCATTTGAATGACTTGTCCATTCCAGTGGATGAG
GAGGACCCTTCAGAAGACATATTTACAGTTTTGACAGCTGAAGAAAAGCAGCGATTGGAA
GAGCTCCAGCTGTTCAAAAATAAGGAAACCAGTGTTGCCATTGAGGTTATCGAGGACACC
AAAGAGAAAAGAACCATCATCCATCAGGCTATCAAATCTCTGTTTCCAGGATTAGAGACA
AAAACAGAGGATAGGGAGGGGAAGAAATACATTGTAGCCTACCACGCAGCTGGGAAAAAG
GCTTTGGCAAATCCAAGAAAACATTCTTGGCCAAAATCTAGGGGAAGTTACTGCCACTTC
GTACTATATAAGGAAAACAAAGACACCATGGATGCTATTAATGTACTCTCCAAATACTTA
AGAGTCAAGCCAAATATATTCTCCTACATGGGAACCAAAGATAAAAGGGCTATAACAGTT
CAAGAAATTGCTGTTCTCAAAATAACTGCACAAAGACTTGCCCACCTGAATAAGTGCTTG
ATGAACTTTAAGCTAGGGAATTTCAGCTATCAAAAAAACCCACTGAAATTGGGAGAGCTT
CAAGGAAACCACTTCACTGTTGTTCTCAGAAATATAACAGGAACTGATGACCAAGTACAG
CAAGCTATGAACTCTCTCAAGGAGATTGGATTTATTAACTACTATGGAATGCAAAGATTT
GGAACCACAGCTGTCCCTACGTATCAGGTTGGAAGAGCTATACTACAAAATTCCTGGACA
GAAGTCATGGATTTAATATTGAAACCCCGCTCTGGAGCTGAAAAGGGCTACTTGGTTAAA
TGCAGAGAAGAATGGGCAAAGACCAAAGACCCAACTGCTGCCCTCAGAAAACTACCTGTC
AAAAGGTGTGTGGAAGGGCAGCTGCTTCGAGGACTTTCAAAATATGGAATGAAGAATATA
GTCTCTGCATTTGGCATAATACCCAGAAATAATCGCTTAATGTATATTCATAGCTACCAA
AGCTATGTGTGGAATAACATGGTAAGCAAGAGGATAGAAGACTATGGACTAAAACCTGTT
CCAGGGGACCTCGTTCTCAAAGGAGCCACAGCCACCTATATTGAGGAAGATGATGTTAAT
AATTACTCTATCCATGATGTGGTAATGCCCTTGCCTGGTTTCGATGTTATCTACCCAAAG
CATAAAATTCAAGAAGCCTACAGGGAAATGCTCACAGCTGACAATCTTGATATTGACAAC
ATGAGACACAAAATTCGAGATTATTCCTTGTCAGGGGCCTACCGAAAGATCATTATTCGT
CCTCAGAATGTTAGCTGGGAAGTCGTTGCATATGATGATCCCAAAATTCCACTTTTCAAC
ACAGATGTGGACAACCTAGAAGGGAAGACACCACCAGTTTTTGCTTCTGAAGGCAAATAC
AGGGCTCTGAAAATGGATTTTTCTCTACCCCCTTCTACTTACGCCACCATGGCCATTCGA
GAAGTGCTAAAAATGGATACCAGTATCAAGAACCAGACGCAGCTGAATACAACCTGGCTT
CGCTGA
|
Protein Properties |
Number of Residues
| 661 |
Molecular Weight
| 75034.9 |
Theoretical pI
| 6.31 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Pseudouridylate synthase 7 homolog
MEMTEMTGVSLKRGALVVEDNDSGVPVEETKKQKLSECSLTKGQDGLQNDFLSISEDVPR
PPDTVSTGKGGKNSEAQLEDEEEEEEDGLSEECEEEESESFADMMKHGLTEADVGITKFV
SSHQGFSGILKERYSDFVVHEIGKDGRISHLNDLSIPVDEEDPSEDIFTVLTAEEKQRLE
ELQLFKNKETSVAIEVIEDTKEKRTIIHQAIKSLFPGLETKTEDREGKKYIVAYHAAGKK
ALANPRKHSWPKSRGSYCHFVLYKENKDTMDAINVLSKYLRVKPNIFSYMGTKDKRAITV
QEIAVLKITAQRLAHLNKCLMNFKLGNFSYQKNPLKLGELQGNHFTVVLRNITGTDDQVQ
QAMNSLKEIGFINYYGMQRFGTTAVPTYQVGRAILQNSWTEVMDLILKPRSGAEKGYLVK
CREEWAKTKDPTAALRKLPVKRCVEGQLLRGLSKYGMKNIVSAFGIIPRNNRLMYIHSYQ
SYVWNNMVSKRIEDYGLKPVPGDLVLKGATATYIEEDDVNNYSIHDVVMPLPGFDVIYPK
HKIQEAYREMLTADNLDIDNMRHKIRDYSLSGAYRKIIIRPQNVSWEVVAYDDPKIPLFN
TDVDNLEGKTPPVFASEGKYRALKMDFSLPPSTYATMAIREVLKMDTSIKNQTQLNTTWL
R
|
External Links |
GenBank ID Protein
| 50727002 |
UniProtKB/Swiss-Prot ID
| Q96PZ0 |
UniProtKB/Swiss-Prot Entry Name
| PUS7_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_019042.3 |
GeneCard ID
| PUS7 |
GenAtlas ID
| PUS7 |
HGNC ID
| HGNC:26033 |
References |
General References
| Not Available |