| Identification |
|---|
| HMDB Protein ID
| CDBP04331 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ferrochelatase |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| Not Available |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ferrochelatase activity |
| Specific Function
| Catalyzes the ferrous insertion into protoporphyrin IX |
| GO Classification
|
| Function |
| catalytic activity |
| lyase activity |
| ferrochelatase activity |
| Process |
| metabolic process |
| nitrogen compound metabolic process |
| tetrapyrrole metabolic process |
| porphyrin metabolic process |
| heme biosynthetic process |
| porphyrin biosynthetic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Not Available |
| Locus
| Not Available |
| SNPs
| Not Available |
| Gene Sequence
|
>1263 bp
CTCGGCGCAAACATGGCTGCGGCCCTGCGCGCCGCGGGCGTCCTGCTCCGCGATCCGCTG
GCATCCAGCAGCTGGAGGGTCTGTCAGCCATGGAGGTGGAAGTCAGGTGCAGCTGCAGCG
GCCGTCACCACAGAAACAGCCCAGCATGCCCAGGGTGCAAAACCTCAAGTTCAACCGCAG
AAGAGGAAGCCGAAAACTGGAATATTAATGCTAAACATGGGAGGCCCTGAAACTCTTGGA
GATGTTCACGACTTCCTTCTGAGACTCTTCTTGGACCGAGACCTCATGACACTTCCTATT
CAGAATAAGCTGGCACCATTCATCGCCAAACGCCGAACCCCCGAGATTCAAGAGCAGTAC
CGCAGGATTGGAGGCGGATCCCCCATCAAGATATGGACTTCCAAGCAGGGAGAGGGCATG
GTGAAGCTGCTGGATGAATTGTCCCCCAACACAGCCCCTCACAAATACTATATTGGATTT
CGGTACGTCCATCCTTTAACAGAAGAAGCAATTGAAGAGATGGAGAGAGATGGCCTAGAA
AGGGCTATTGCTTTCACACAGTATCCACAGTACAGCTGCTCCACCACAGGCAGCAGCTTA
AATGCCATTTACAGATACTATAATCAAGTGGGACGGAAGCCCACGATGAAGTGGAGCACT
ATTGACAGGTGGCCCACACATCACCTCCTCATCCAGTGCTTTGCAGATCATATTCTAAAG
GAACTGGACCATTTTCCACTTGAGAAGAGAAGCGAGGTGGTCATTCTGTTTTCTGCTCAC
TCACTGCCCATGTCTGTGGTCAACAGAGGCGACCCATATCCTCAGGAGGTAAGCGCCACT
GTCCAAAAAGTCATGGAAAGGCTGGAGTACTGCAACCCCTACCGACTGGTGTGGCAATCC
AAGGTTGGTCCAATGCCCTGGTTGGGTCCTCAAACAGACGAATCTATCAAAGGGCTTTGT
GAGAGGGGGAGGAAGAATATCCTCTTGGTTCCGATAGCATTTACCAGTGACCATATTGAA
ACGCTGTATGAGCTGGACATCGAGTACTCTCAAGTTTTAGCCAAGGAGTGTGGAGTTGAA
AACATCAGAAGAGCTGAGTCTCTTAATGGAAATCCATTGTTCTCTAAGGCCCTGGCCGAC
TTGGTGCATTCACACATCCAGTCAAACGAGCTGTGTTCCAAGCAGCTGACCCTGAGCTGT
CCGCTCTGTGTCAATCCTGTCTGCAGGGAGACTAAATCCTTCTTCACCAGCCAGCAGCTG
TGA
|
| Protein Properties |
|---|
| Number of Residues
| 420 |
| Molecular Weight
| 47488.3 |
| Theoretical pI
| 8.53 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Ferrochelatase
LGANMAAALRAAGVLLRDPLASSSWRVCQPWRWKSGAAAAAVTTETAQHAQGAKPQVQPQ
KRKPKTGILMLNMGGPETLGDVHDFLLRLFLDRDLMTLPIQNKLAPFIAKRRTPEIQEQY
RRIGGGSPIKIWTSKQGEGMVKLLDELSPNTAPHKYYIGFRYVHPLTEEAIEEMERDGLE
RAIAFTQYPQYSCSTTGSSLNAIYRYYNQVGRKPTMKWSTIDRWPTHHLLIQCFADHILK
ELDHFPLEKRSEVVILFSAHSLPMSVVNRGDPYPQEVSATVQKVMERLEYCNPYRLVWQS
KVGPMPWLGPQTDESIKGLCERGRKNILLVPIAFTSDHIETLYELDIEYSQVLAKECGVE
NIRRAESLNGNPLFSKALADLVHSHIQSNELCSKQLTLSCPLCVNPVCRETKSFFTSQQL
|
| External Links |
|---|
| GenBank ID Protein
| 62897941 |
| UniProtKB/Swiss-Prot ID
| Q53FU1 |
| UniProtKB/Swiss-Prot Entry Name
| Q53FU1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK223190 |
| GeneCard ID
| Not Available |
| GenAtlas ID
| Not Available |
| HGNC ID
| HGNC:3647 |
| References |
|---|
| General References
| Not Available |