Identification |
HMDB Protein ID
| CDBP04318 |
Secondary Accession Numbers
| Not Available |
Name
| Putative neutral ceramidase C |
Description
| Not Available |
Synonyms
|
- N-acylsphingosine amidohydrolase 2C
- Non-lysosomal ceramidase C
|
Gene Name
| ASAH2C |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in ceramidase activity |
Specific Function
| May hydrolyze the sphingolipid ceramide into sphingosine and free fatty acid (By similarity).
|
GO Classification
|
Biological Process |
sphingolipid metabolic process |
Molecular Function |
ceramidase activity |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| ASAH2C |
Gene Sequence
|
>1833 bp
GTCCTGAACAGACTGCAGAGTAAATATGGCTCCCTGTACAGAAGAGATAATGTCATCCTG
AGTGGCACTCACACTCATTCAGGTCCTGCAGGATATTTCCAGTATACCGTGTTTGTAATT
GCCAGTGAAGGATTTAGCAATCAAACTTTTCAGCACATGGTCACTGGTATCTTGAAGAGC
ATTGACATAGCACACACAAATATGAAACCAGGCAAAATCTTCATCAATAAAGGAAATGTG
GATGGTGTGCAGATCAACAGAAGTCCGTATTCTTACCTTCAAAATCCGCAGTCAGAGAGA
GCAAGGTATTCTTCAAATACAGACAAGGAAATGATAGTTTTGAAAATGGTAGATTTGAAT
GGAGATGACTTGGGCCTTATCAGCTGGTTTGCCATCCACCCGGTCAGCATGAACAACAGT
AACCATCTTGTAAACAGTGACAATGTGGGCTATGCATCTTACCTGCTTGAGCAAGAGAAG
AACAAAGGATATCTACCTGGACAGGGGCCATTTGTAGCAGCCTTTTCTTCATCAAACCTA
GGAGATGTGTCCCCCAACATTCTTGGACCACGTTGCATCAACACAGGAGAGTCCTGTGAT
AACGCCAATAGCACTTGTCCCATTGGTGGGCCTAGCATGTGCATTGCTAAGGGACCTGGA
CAGGATATGTTTGACAGCACACAAATTATAGGACGGGCCATGTATCAGAGAGCAAAGGAA
CTCTATGCCTCTGCCTCCCAGGAGGTAACAGGACCACTGGCTTCAGCACACCAGTGGGTG
GATATGACAGATGTGACTGTCTGGCTCAATTCCACACATGCATCAAAAACATGTAAACCA
GCATTGGGCTACAGTTTTGCGGCTGGCACTATTGATGGAGTTGGAGGCCTCAATTTTACA
CAGGGGAAAACAGAAGGGGATCCATTTTGGGACACCATTCGGGACCAGATCCTGGGAAAG
CCATCTGAAGAAATTAAAGAATGTCATAAACCAAAGCCCATCCTTCTTCACACCGGAGAA
CTATCAAAACCTCACCCCTGGCATCCAGACATTGTTGATGTTCAGATTATTACCCTTGGG
TCCTTGGCCATAACTGCCATCCCCGGGGAGTTTACGACCATGTCTGGACGAAGACTTCGA
GAGGCAGTTCAAGCAGAATTTGCATCTCATGGGATGCAGAACATGACTGTTGTTATTTCA
GGTCTATGCAACGTCTATACACATTACATTACCACTTATGAAGAATACCAGGCTCAGCGA
TATGAGGCAGCATCGACAATTTATGGACCGCACACATTATCTGCTTACATTCAGCTCTTC
AGAAACCTTGCTAAGGCTATTGCTACGGACACGGTAGCCAACCTGAGCAGAGGTCCAGAA
CCTCCCTTTTTCAAACAATTAATAGTTCCATTAATTCCTAGTATTGTGGATAGAGCACCA
AAAGGCAGAACTTTCGGGGATGTCCTGCAGCCAGCAAAACCTGAATACAGAGTGGGGGAA
GTTGCTGAAGTTATATTTGTAGGTGCTAACCCGAAGAATTCAGTACAAAACCAGAACCAT
CAGACCTTCCTCACTGTGGAGAAATATGAGGCTACTTCAACATCGTGGCAGATAGTGTGT
AATGATGCCTCCTGGGAGACTCGTTTTTATTGGCACAAGGGACTCCTGGGTCTGAGTAAT
GCAACAGTGGAATGGCATATTCCAGACACTGCCCAGCCTGGAATCTACAGAATAAGATAT
TTTGGACACAATCGGAAGCAGGACATTCTGAAGCCTGCTGTCATACTTTCATTTGAAGGC
ACTTCCCCGGCTTTTGAAGTTGTAACTATTTAG
|
Protein Properties |
Number of Residues
| 622 |
Molecular Weight
| Not Available |
Theoretical pI
| Not Available |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Putative neutral ceramidase C
MDSEKSSEWRSDVLNRLQSKYGSLYRRDNVILSGTHTHSGPAGYFQYTVFVIASEGFSNQ
TFQHMVTGILKSIDIAHTNMKPGKIFINKGNVDGVQINRSPYSYLQNPQSERARYSSNTD
KEMIVLKMVDLNGDDLGLISWFAIHPVSMNNSNHLVNSDNVGYASYLLEQEKNKGYLPGQ
GPFVAAFSSSNLGDVSPNILGPRCINTGESCDNANSTCPIGGPSMCIAKGPGQDMFDSTQ
IIGRAMYQRAKELYASASQEVTGPLASAHQWVDMTDVTVWLNSTHASKTCKPALGYSFAA
GTIDGVGGLNFTQGKTEGDPFWDTIRDQILGKPSEEIKECHKPKPILLHTGELSKPHPWH
PDIVDVQIITLGSLAITAIPGEFTTMSGRRLREAVQAEFASHGMQNMTVVISGLCNVYTH
YITTYEEYQAQRYEAASTIYGPHTLSAYIQLFRNLAKAIATDTVANLSRGPEPPFFKQLI
VPLIPSIVDRAPKGRTFGDVLQPAKPEYRVGEVAEVIFVGANPKNSVQNQNHQTFLTVEK
YEATSTSWQIVCNDASWETRFYWHKGLLGLSNATVEWHIPDTAQPGIYRIRYFGHNRKQD
ILKPAVILSFEGTSPAFEVVTI
|
External Links |
GenBank ID Protein
| 55962226 |
UniProtKB/Swiss-Prot ID
| P0C7U2 |
UniProtKB/Swiss-Prot Entry Name
| ASA2C_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL954360 |
GeneCard ID
| ASAH2C |
GenAtlas ID
| ASAH2C |
HGNC ID
| HGNC:23457 |
References |
General References
| Not Available |