| Identification |
|---|
| HMDB Protein ID
| CDBP04312 |
| Secondary Accession Numbers
| Not Available |
| Name
| Dipeptidase 2 |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| DPEP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in metalloexopeptidase activity |
| Specific Function
| Probable metalloprotease which hydrolyzes leukotriene D4 (LTD4) into leukotriene E4 (LTE4) |
| GO Classification
|
| Function |
| peptidase activity, acting on l-amino acid peptides |
| metallopeptidase activity |
| metalloexopeptidase activity |
| exopeptidase activity |
| catalytic activity |
| hydrolase activity |
| dipeptidase activity |
| dipeptidyl-peptidase activity |
| peptidase activity |
| Process |
| metabolic process |
| macromolecule metabolic process |
| protein metabolic process |
| proteolysis |
|
| Cellular Location
|
- Lipid-anchor
- GPI-anchor
- Membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 16q22.1 |
| SNPs
| DPEP2 |
| Gene Sequence
|
>1461 bp
ATGCAGCCCTCCGGCCTCGAGGGTCCCGGCACGTTTGGTCGGTGGCCTCTGCTGAGTCTG
CTGCTCCTGCTGCTGCTGCTCCAGCCTGTAACCTGTGCCTACACCACGCCAGGCCCCCCC
AGAGCCCTCACCACGCTGGGCGCCCCCAGAGCCCACACCATGCCGGGCACCTACGCTCCC
TCGACCACACTCAGTAGTCCCAGCACCCAGGGCCTGCAAGAGCAGGCACGGGCCCTGATG
CGGGACTTCCCGCTCGTGGACGGCCACAACGACCTGCCCCTGGTCCTAAGGCAGGTTTAC
CAGAAAGGGCTACAGGATGTTAACCTGCGCAATTTCAGCTACGGCCAGACCAGCCTGGAC
AGGCTTAGAGATGGCCTCGTGGGCGCCCAGTTCTGGTCAGCCTATGTGCCATGCCAGACC
CAGGACCGGGATGCCCTGCGCCTCACCCTGGAGCAGATTGACCTCATACGCCGCATGTGT
GCCTCCTATTCTGAGCTGGAGCTTGTGACCTCGGCTAAAGCTCTGAACGACACTCAGAAA
TTGGCCTGCCTCATCGGTGTAGAGGGTGGCCACTCGCTGGACAATAGCCTCTCCATCTTA
CGTACCTTCTACATGCTGGGAGTGCGCTACCTGACGCTCACCCACACCTGCAACACACCC
TGGGCAGAGAGCTCCGCTAAGGGCGTCCACTCCTTCTACAACAACATCAGCGGGCTGACT
GACTTTGGTGAGAAGGTGGTGGCAGAAATGAACCGCCTGGGCATGATGGTAGACTTATCC
CATGTCTCAGATGCTGTGGCACGGCGGGCCCTGGAAGTGTCACAGGCACCTGTGATCTTC
TCCCACTCGGCTGCCCGGGGTGTGTGCAACAGTGCTCGGAATGTTCCTGATGACATCCTG
CAGCTTCTGAAGAAGAACGGTGGCGTCGTGATGGTGTCTTTGTCCATGGGAGTAATACAG
TGCAACCCATCAGCCAATGTGTCCACTGTGGCAGATCACTTCGACCACATCAAGGCTGTC
ATTGGATCCAAGTTCATCGGGATTGGTGGAGATTATGATGGGGCCGGCAAATTCCCTCAG
GGGCTGGAAGACGTGTCCACATACCCGGTCCTGATAGAGGAGTTGCTGAGTCGTGGCTGG
AGTGAGGAAGAGCTTCAGGGTGTCCTTCGTGGAAACCTGCTGCGGGTCTTCAGACAAGTG
GAAAAGGTACAGGAAGAAAACAAATGGCAAAGCCCCTTGGAGGACAAGTTCCCGGATGAG
CAGCTGAGCAGTTCCTGCCACTCCGACCTCTCACGTCTGCGTCAGAGACAGAGTCTGACT
TCAGGCCAGGAACTCACTGAGATTCCCATACACTGGACAGCCAAGTTACCAGCCAAGTGG
TCAGTCTCAGAGTCCTCCCCCCACATGGCCCCAGTCCTTGCAGTTGTGGCCACCTTCCCA
GTCCTTATTCTGTGGCTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 486 |
| Molecular Weight
| 53305.5 |
| Theoretical pI
| 6.37 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>Dipeptidase 2
MQPSGLEGPGTFGRWPLLSLLLLLLLLQPVTCAYTTPGPPRALTTLGAPRAHTMPGTYAP
STTLSSPSTQGLQEQARALMRDFPLVDGHNDLPLVLRQVYQKGLQDVNLRNFSYGQTSLD
RLRDGLVGAQFWSAYVPCQTQDRDALRLTLEQIDLIRRMCASYSELELVTSAKALNDTQK
LACLIGVEGGHSLDNSLSILPTFYMLGVRYLTLTHTCNTPWAESSAKGVHSFYNNISGLT
DFGEKVVAEMNRLGMMVDLSHVSDAVARRALEVSQAPVIFSHSAARGVCNSARNVPDDIL
QLLKKNGGVVMVSLSMGVIQCNPSANVSTVADHFDHIKAVIGSKFIGIGGDYDGAGKFPQ
GLEDVSTYPVLIEELLSRGWSEEELQGVLRGNLLRVFRQVEKVQEENKWQSPLEDKFPDE
QLSSSCHSDLSRLRQRQSLTSGQELTEIPIHWTAKLPAKWSVSESSPHMAPVLAVVATFP
VLILWL
|
| External Links |
|---|
| GenBank ID Protein
| 11641269 |
| UniProtKB/Swiss-Prot ID
| Q9H4A9 |
| UniProtKB/Swiss-Prot Entry Name
| DPEP2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_022355.2 |
| GeneCard ID
| DPEP2 |
| GenAtlas ID
| DPEP2 |
| HGNC ID
| HGNC:23028 |
| References |
|---|
| General References
| Not Available |