Identification
HMDB Protein ID CDBP04293
Secondary Accession Numbers Not Available
Name 2-oxoglutarate receptor 1
Description Not Available
Synonyms
  1. Alpha-ketoglutarate receptor 1
  2. G-protein coupled receptor 80
  3. G-protein coupled receptor 99
  4. P2Y purinoceptor 15
  5. P2Y-like GPCR
  6. P2Y-like nucleotide receptor
  7. P2Y15
Gene Name OXGR1
Protein Type Receptor
Biological Properties
General Function Involved in G-protein coupled receptor protein signaling pathway
Specific Function Receptor for alpha-ketoglutarate. Seems to act exclusively through a G(q)-mediated pathway
GO Classification
Component
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
nucleotide receptor activity, g-protein coupled
purinergic nucleotide receptor activity, g-protein coupled
receptor activity
transmembrane receptor activity
molecular transducer activity
signal transducer activity
g-protein coupled receptor activity
Process
signaling
signaling pathway
cell surface receptor linked signaling pathway
g-protein coupled receptor protein signaling pathway
Cellular Location
  1. Cell membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 13q32.1
SNPs OXGR1
Gene Sequence
>1014 bp
ATGAATGAGCCACTAGACTATTTAGCAAATGCTTCTGATTTCCCCGATTATGCAGCTGCT
TTTGGAAATTGCACTGATGAAAACATCCCACTCAAGATGCACTACCTCCCTGTTATTTAT
GGCATTATCTTCCTCGTGGGATTTCCAGGCAATGCAGTAGTGATATCCACTTACATTTTC
AAAATGAGACCTTGGAAGAGCAGCACCATCATTATGCTGAACCTGGCCTGCACAGATCTG
CTGTATCTGACCAGCCTCCCCTTCCTGATTCACTACTATGCCAGTGGCGAAAACTGGATC
TTTGGAGATTTCATGTGTAAGTTTATCCGCTTCAGCTTCCATTTCAACCTGTATAGCAGC
ATCCTCTTCCTCACCTGTTTCAGCATCTTCCGCTACTGTGTGATCATTCACCCAATGAGC
TGCTTTTCCATTCACAAAACTCGATGTGCAGTTGTAGCCTGTGCTGTGGTGTGGATCATT
TCACTGGTAGCTGTCATTCCGATGACCTTCTTGATCACATCAACCAACAGGACCAACAGA
TCAGCCTGTCTCGACCTCACCAGTTCGGATGAACTCAATACTATTAAGTGGTACAACCTG
ATTTTGACTGCAACTACTTTCTGCCTCCCCTTGGTGATAGTGACACTTTGCTATACCACG
ATTATCCACACTCTGACCCATGGACTGCAAACTGACAGCTGCCTTAAGCAGAAAGCACGA
AGGCTAACCATTCTGCTACTCCTTGCATTTTACGTATGTTTTTTACCCTTCCATATCTTG
AGGGTCATTCGGATCGAATCTCGCCTGCTTTCAATCAGTTGTTCCATTGAGAATCAGATC
CATGAAGCTTACATCGTTTCTAGACCATTAGCTGCTCTGAACACCTTTGGTAACCTGTTA
CTATATGTGGTGGTCAGCGACAACTTTCAGCAGGCTGTCTGCTCAACAGTGAGATGCAAA
GTAAGCGGGAACCTTGAGCAAGCAAAGAAAATTAGTTACTCAAACAACCCTTGA
Protein Properties
Number of Residues 337
Molecular Weight 38250.6
Theoretical pI 8.23
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["35-55", "70-90", "117-137", "152-172", "202-222", "243-263", "285-305"]
Protein Sequence
>2-oxoglutarate receptor 1
MNEPLDYLANASDFPDYAAAFGNCTDENIPLKMHYLPVIYGIIFLVGFPGNAVVISTYIF
KMRPWKSSTIIMLNLACTDLLYLTSLPFLIHYYASGENWIFGDFMCKFIRFSFHFNLYSS
ILFLTCFSIFRYCVIIHPMSCFSIHKTRCAVVACAVVWIISLVAVIPMTFLITSTNRTNR
SACLDLTSSDELNTIKWYNLILTATTFCLPLVIVTLCYTTIIHTLTHGLQTDSCLKQKAR
RLTILLLLAFYVCFLPFHILRVIRIESRLLSISCSIENQIHEAYIVSRPLAALNTFGNLL
LYVVVSDNFQQAVCSTVRCKVSGNLEQAKKISYSNNP
GenBank ID Protein 21929019
UniProtKB/Swiss-Prot ID Q96P68
UniProtKB/Swiss-Prot Entry Name OXGR1_HUMAN
PDB IDs Not Available
GenBank Gene ID AB065877
GeneCard ID OXGR1
GenAtlas ID OXGR1
HGNC ID HGNC:4531
References
General References Not Available