| Identification |
|---|
| HMDB Protein ID
| CDBP04287 |
| Secondary Accession Numbers
| Not Available |
| Name
| Solute carrier family 10 member 6 |
| Description
| Not Available |
| Synonyms
|
- Sodium-dependent organic anion transporter
|
| Gene Name
| SLC10A6 |
| Protein Type
| Transporter |
| Biological Properties |
|---|
| General Function
| Involved in bile acid:sodium symporter activity |
| Specific Function
| Transports sulfoconjugated steroid hormones, as well as taurolithocholic acid-3-sulfate and sulfoconjugated pyrenes in a sodium-dependent manner |
| GO Classification
|
| Component |
| cell part |
| membrane |
| Function |
| transmembrane transporter activity |
| substrate-specific transmembrane transporter activity |
| organic acid:sodium symporter activity |
| transporter activity |
| bile acid:sodium symporter activity |
| organic acid transmembrane transporter activity |
| Process |
| sodium ion transport |
| establishment of localization |
| transport |
| monovalent inorganic cation transport |
| ion transport |
| cation transport |
|
| Cellular Location
|
- Membrane
- Multi-pass membrane protein (Potential)
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:4 |
| Locus
| 4q21.3 |
| SNPs
| SLC10A6 |
| Gene Sequence
|
>1134 bp
ATGAGAGCCAATTGTTCCAGCAGCTCAGCCTGCCCTGCCAACAGTTCAGAGGAGGAGCTG
CCAGTGGGACTGGAGGTGCATGGAAACCTGGAGCTCGTTTTCACAGTGGTGTCCACTGTG
ATGATGGGGCTGCTCATGTTCTCTTTGGGATGTTCCGTGGAGATCCGGAAGCTGTGGTCG
CACATCAGGAGACCCTGGGGCATTGCTGTGGGACTGCTCTGCCAGTTTGGGCTCATGCCT
TTTACAGCTTATCTCCTGGCCATTAGCTTTTCTCTGAAGCCAGTCCAAGCTATTGCTGTT
CTCATCATGGGCTGCTGCCCGGGGGGCACCATCTCTAACATTTTCACCTTCTGGGTTGAT
GGAGATATGGATCTCAGCATCAGTATGACAACCTGTTCCACCGTGGCCGCCCTGGGAATG
ATGCCACTCTGCATTTATCTCTACACCTGGTCCTGGAGTCTTCAGCAGAATCTCACCATT
CCTTATCAGAACATAGGAATTACCCTTGTGTGCCTGACCATTCCTGTGGCCTTTGGTGTC
TATGTGAATTACAGATGGCCAAAACAATCCAAAATCATTCTCAAGATTGGGGCCGTTGTT
GGTGGGGTCCTCCTTCTGGTGGTCGCAGTTGCTGGTGTGGTCCTGGCGAAAGGATCTTGG
AATTCAGACATCACCCTTCTGACCATCAGTTTCATCTTTCCTTTGATTGGCCATGTCACG
GGTTTTCTGCTGGCACTTTTTACCCACCAGTCTTGGCAAAGGTGCAGGACAATTTCCTTA
GAAACTGGAGCTCAGAATATTCAGATGTGCATCACCATGCTCCAGTTATCTTTCACTGCT
GAGCACTTGGTCCAGATGTTGAGTTTCCCACTGGCCTATGGACTCTTCCAGCTGATAGAT
GGATTTCTTATTGTTGCAGCATATCAGACGTACAAGAGGAGATTGAAGAACAAACATGGA
AAAAAGAACTCAGGTTGCACAGAAGTCTGCCATACGAGGAAATCGACTTCTTCCAGAGAG
ACCAATGCCTTCTTGGAGGTGAATGAAGAAGGTGCCATCACTCCTGGGCCACCAGGGCCA
ATGGATTGCCACAGGGCTCTCGAGCCAGTTGGCCACATCACTTCATGTGAATAG
|
| Protein Properties |
|---|
| Number of Residues
| 377 |
| Molecular Weight
| 41258.2 |
| Theoretical pI
| 7.91 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
- ["30-50", "68-88", "98-118", "134-154", "160-180", "196-216", "227-247", "267-285", "291-311"]
|
| Protein Sequence
|
>Solute carrier family 10 member 6
MRANCSSSSACPANSSEEELPVGLEVHGNLELVFTVVSTVMMGLLMFSLGCSVEIRKLWS
HIRRPWGIAVGLLCQFGLMPFTAYLLAISFSLKPVQAIAVLIMGCCPGGTISNIFTFWVD
GDMDLSISMTTCSTVAALGMMPLCIYLYTWSWSLQQNLTIPYQNIGITLVCLTIPVAFGV
YVNYRWPKQSKIILKIGAVVGGVLLLVVAVAGVVLAKGSWNSDITLLTISFIFPLIGHVT
GFLLALFTHQSWQRCRTISLETGAQNIQMCITMLQLSFTAEHLVQMLSFPLAYGLFQLID
GFLIVAAYQTYKRRLKNKHGKKNSGCTEVCHTRKSTSSRETNAFLEVNEEGAITPGPPGP
MDCHRALEPVGHITSCE
|
| External Links |
|---|
| GenBank ID Protein
| 35208821 |
| UniProtKB/Swiss-Prot ID
| Q3KNW5 |
| UniProtKB/Swiss-Prot Entry Name
| SOAT_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AJ583502 |
| GeneCard ID
| SLC10A6 |
| GenAtlas ID
| SLC10A6 |
| HGNC ID
| HGNC:30603 |
| References |
|---|
| General References
| Not Available |