Identification
HMDB Protein ID CDBP04268
Secondary Accession Numbers Not Available
Name Sodium-dependent neutral amino acid transporter B(0)AT3
Description Not Available
Synonyms
  1. Sodium- and chloride-dependent transporter XTRP2
  2. Solute carrier family 6 member 18
  3. System B(0) neutral amino acid transporter AT3
Gene Name SLC6A18
Protein Type Transporter
Biological Properties
General Function Involved in neurotransmitter:sodium symporter activity
Specific Function Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity).
GO Classification
Biological Process
amino acid transport
response to osmotic stress
transmembrane transport
Cellular Component
plasma membrane
integral to plasma membrane
Component
integral to plasma membrane
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
neurotransmitter:sodium symporter activity
transmembrane transporter activity
transporter activity
neurotransmitter transporter activity
Molecular Function
neurotransmitter:sodium symporter activity
Process
establishment of localization
transport
neurotransmitter transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein (Probable)
Pathways
Gene Properties
Chromosome Location 5
Locus 5p15.33
SNPs SLC6A18
Gene Sequence
>1887 bp
ATGGCTCATGCCCCAGAACCGGACCCGGCCGCCTGCGACCTCGGGGATGAGAGGCCCAAG
TGGGACAACAAGGCCCAGTACCTCCTGAGCTGCATTGGGTTTGCCGTGGGGCTGGGGAAC
ATTTGGCGGTTCCCATACCTGTGCCAGACCTATGGAGGAGGGGCCTTCCTCATCCCCTAC
GTCATCGCGCTGGTCTTCGAGGGGATCCCCATTTTCCACGTCGAGCTCGCCATCGGCCAG
CGGCTGCGGAAGGGCAGCGTCGGCGTGTGGACGGCCATCTCCCCGTACCTCAGTGGAGTA
GGGCTGGGCTGTGTCACGCTGTCCTTCCTGATCAGCCTGTACTACAACACCATCGTGGCG
TGGGTGCTGTGGTACCTCCTCAACTCCTTCCAGCACCCGCTGCCCTGGAGCTCCTGCCCA
CCGGACCTCAACAGAACAGGGTTTGTGGAGGAGTGCCAGGGCAGCAGCGCCGTGAGCTAC
TTCTGGTACCGGCAGACACTGAACATCACAGCCGACATCAATGACAGTGGCTCCATCCAG
TGGTGGCTGCTCATCTGCTTGGCAGCCTCCTGGGCAGTCGTGTACATGTGTGTCATCAGG
GGCATTGAGACTACAGGGAAGGTGATTTACTTCACAGCTTTGTTCCCTTACCTGGTCCTG
ACCATCTTTCTCATCAGAGGGCTGACCCTGCCAGGGGCAACAAAAGGACTCATCTACTTG
TTCACTCCCAACATGCACATTCTCCAGAACCCCCGGGTGTGGCTGGACGCAGCCACCCAG
ATATTCTTCTCTCTGTCCCTGGCCTTCGGAGGACACATCGCTTTTGCAAGTTACAACTCG
CCCAGGAATGACTGCCAGAAGGATGCGGTGGTCATCGCCCTGGTCAACAGGATGACCTCC
CTGTACGCGTCCATCGCTGTCTTCTCTGTCCTGGGGTTCAAAGCAACTAATGACTACGAG
CACTGCCTGGACAGAAACATCCTCAGCCTCATCAACGACTTTGACTTCCCAGAGCAGAGC
ATCTCCAGGGACGACTACCCAGCCGTCCTCATGCACCTGAACGCCACCTGGCCCAAGAGG
GTGGCCCAGCTCCCCCTGAAGGCCTGCCTCCTGGAAGACTTTCTGGATAAGAGTGCCTCG
GGCCCGGGCCTGGCCTTCGTCGTCTTCACGGAGACCGACCTCCACATGCCGGGGGCTCCT
GTGTGGGCCATGCTCTTCTTCGGGATGCTGTTCACCTTGGGGCTATCGACCATGTTCGGG
ACCGTGGAGGCGGTCATCACACCCCTGCTGGACGTGGGGGTCCTGCCTAGATGGGTCCCC
AAGGAGGCCCTGACTGGGCTGGTCTGCCTGGTCTGCTTCCTCTCCGCCACCTGCTTCACG
CTGCAGTCTGGGAACTACTGGCTGGAGATTTTCGACAATTTTGCCGCTTCCCTGAACCTG
CTCATGTTGGCCTTTCTCGAGGTTGTGGGTGTCGTTTATGTTTATGGAATGAAACGGTTC
TGCGATGACATTGCGTGGATGACCGGGAGGCGGCCCAGCCCCTACTGGCGGCTGACCTGG
AGGGTGGTCAGTCCCCTGCTGCTGACCATCTTTGTGGCTTACATCATCCTCCTGTTCTGG
AAGCCACTGAGATACAAGGCCTGGAACCCCAAATACGAGCTGTTCCCCTCGCGTCAGGAG
AAGCTCTACCCGGGCTGGGCGCGCGCCGCCTGTGTGCTGCTGTCCTTGCTGCCCGTGCTG
TGGGTCCCGGTGGCCGCGCTTGCTCAGCTGCTCACCCGGCGGAGGCGGACGTGGAGGGAC
AGGGACGCGCGCCCAGACACGGACATGCGCCCGGACACGGACACGCGCCCAGACACGGAC
ATGCGCCCGGACACGGACATGCGCTGA
Protein Properties
Number of Residues 628
Molecular Weight 70896.005
Theoretical pI 7.291
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence
>Sodium-dependent neutral amino acid transporter B(0)AT3
MAHAPEPDPAACDLGDERPKWDNKAQYLLSCIGFAVGLGNIWRFPYLCQTYGGGAFLIPY
VIALVFEGIPIFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVA
WVLWYLLNSFQHPLPWSSCPPDLNRTGFVEECQGSSAVSYFWYRQTLNITADINDSGSIQ
WWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYL
FTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTS
LYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKR
VAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFG
TVEAVITPLLDVGVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASLNL
LMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLTIFVAYIILLFW
KPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALAQLLTRRRRTWRD
RDARPDTDMRPDTDTRPDTDMRPDTDMR
GenBank ID Protein 16550619
UniProtKB/Swiss-Prot ID Q96N87
UniProtKB/Swiss-Prot Entry Name S6A18_HUMAN
PDB IDs Not Available
GenBank Gene ID AK055798
GeneCard ID SLC6A18
GenAtlas ID SLC6A18
HGNC ID HGNC:26441
References
General References Not Available