Identification |
HMDB Protein ID
| CDBP04268 |
Secondary Accession Numbers
| Not Available |
Name
| Sodium-dependent neutral amino acid transporter B(0)AT3 |
Description
| Not Available |
Synonyms
|
- Sodium- and chloride-dependent transporter XTRP2
- Solute carrier family 6 member 18
- System B(0) neutral amino acid transporter AT3
|
Gene Name
| SLC6A18 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in neurotransmitter:sodium symporter activity |
Specific Function
| Functions as a sodium and chloride-dependent neutral amino acid transporter (By similarity).
|
GO Classification
|
Biological Process |
amino acid transport |
response to osmotic stress |
transmembrane transport |
Cellular Component |
plasma membrane |
integral to plasma membrane |
Component |
integral to plasma membrane |
membrane |
cell part |
membrane part |
intrinsic to membrane |
integral to membrane |
Function |
neurotransmitter:sodium symporter activity |
transmembrane transporter activity |
transporter activity |
neurotransmitter transporter activity |
Molecular Function |
neurotransmitter:sodium symporter activity |
Process |
establishment of localization |
transport |
neurotransmitter transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein (Probable)
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 5 |
Locus
| 5p15.33 |
SNPs
| SLC6A18 |
Gene Sequence
|
>1887 bp
ATGGCTCATGCCCCAGAACCGGACCCGGCCGCCTGCGACCTCGGGGATGAGAGGCCCAAG
TGGGACAACAAGGCCCAGTACCTCCTGAGCTGCATTGGGTTTGCCGTGGGGCTGGGGAAC
ATTTGGCGGTTCCCATACCTGTGCCAGACCTATGGAGGAGGGGCCTTCCTCATCCCCTAC
GTCATCGCGCTGGTCTTCGAGGGGATCCCCATTTTCCACGTCGAGCTCGCCATCGGCCAG
CGGCTGCGGAAGGGCAGCGTCGGCGTGTGGACGGCCATCTCCCCGTACCTCAGTGGAGTA
GGGCTGGGCTGTGTCACGCTGTCCTTCCTGATCAGCCTGTACTACAACACCATCGTGGCG
TGGGTGCTGTGGTACCTCCTCAACTCCTTCCAGCACCCGCTGCCCTGGAGCTCCTGCCCA
CCGGACCTCAACAGAACAGGGTTTGTGGAGGAGTGCCAGGGCAGCAGCGCCGTGAGCTAC
TTCTGGTACCGGCAGACACTGAACATCACAGCCGACATCAATGACAGTGGCTCCATCCAG
TGGTGGCTGCTCATCTGCTTGGCAGCCTCCTGGGCAGTCGTGTACATGTGTGTCATCAGG
GGCATTGAGACTACAGGGAAGGTGATTTACTTCACAGCTTTGTTCCCTTACCTGGTCCTG
ACCATCTTTCTCATCAGAGGGCTGACCCTGCCAGGGGCAACAAAAGGACTCATCTACTTG
TTCACTCCCAACATGCACATTCTCCAGAACCCCCGGGTGTGGCTGGACGCAGCCACCCAG
ATATTCTTCTCTCTGTCCCTGGCCTTCGGAGGACACATCGCTTTTGCAAGTTACAACTCG
CCCAGGAATGACTGCCAGAAGGATGCGGTGGTCATCGCCCTGGTCAACAGGATGACCTCC
CTGTACGCGTCCATCGCTGTCTTCTCTGTCCTGGGGTTCAAAGCAACTAATGACTACGAG
CACTGCCTGGACAGAAACATCCTCAGCCTCATCAACGACTTTGACTTCCCAGAGCAGAGC
ATCTCCAGGGACGACTACCCAGCCGTCCTCATGCACCTGAACGCCACCTGGCCCAAGAGG
GTGGCCCAGCTCCCCCTGAAGGCCTGCCTCCTGGAAGACTTTCTGGATAAGAGTGCCTCG
GGCCCGGGCCTGGCCTTCGTCGTCTTCACGGAGACCGACCTCCACATGCCGGGGGCTCCT
GTGTGGGCCATGCTCTTCTTCGGGATGCTGTTCACCTTGGGGCTATCGACCATGTTCGGG
ACCGTGGAGGCGGTCATCACACCCCTGCTGGACGTGGGGGTCCTGCCTAGATGGGTCCCC
AAGGAGGCCCTGACTGGGCTGGTCTGCCTGGTCTGCTTCCTCTCCGCCACCTGCTTCACG
CTGCAGTCTGGGAACTACTGGCTGGAGATTTTCGACAATTTTGCCGCTTCCCTGAACCTG
CTCATGTTGGCCTTTCTCGAGGTTGTGGGTGTCGTTTATGTTTATGGAATGAAACGGTTC
TGCGATGACATTGCGTGGATGACCGGGAGGCGGCCCAGCCCCTACTGGCGGCTGACCTGG
AGGGTGGTCAGTCCCCTGCTGCTGACCATCTTTGTGGCTTACATCATCCTCCTGTTCTGG
AAGCCACTGAGATACAAGGCCTGGAACCCCAAATACGAGCTGTTCCCCTCGCGTCAGGAG
AAGCTCTACCCGGGCTGGGCGCGCGCCGCCTGTGTGCTGCTGTCCTTGCTGCCCGTGCTG
TGGGTCCCGGTGGCCGCGCTTGCTCAGCTGCTCACCCGGCGGAGGCGGACGTGGAGGGAC
AGGGACGCGCGCCCAGACACGGACATGCGCCCGGACACGGACACGCGCCCAGACACGGAC
ATGCGCCCGGACACGGACATGCGCTGA
|
Protein Properties |
Number of Residues
| 628 |
Molecular Weight
| 70896.005 |
Theoretical pI
| 7.291 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Sodium-dependent neutral amino acid transporter B(0)AT3
MAHAPEPDPAACDLGDERPKWDNKAQYLLSCIGFAVGLGNIWRFPYLCQTYGGGAFLIPY
VIALVFEGIPIFHVELAIGQRLRKGSVGVWTAISPYLSGVGLGCVTLSFLISLYYNTIVA
WVLWYLLNSFQHPLPWSSCPPDLNRTGFVEECQGSSAVSYFWYRQTLNITADINDSGSIQ
WWLLICLAASWAVVYMCVIRGIETTGKVIYFTALFPYLVLTIFLIRGLTLPGATKGLIYL
FTPNMHILQNPRVWLDAATQIFFSLSLAFGGHIAFASYNSPRNDCQKDAVVIALVNRMTS
LYASIAVFSVLGFKATNDYEHCLDRNILSLINDFDFPEQSISRDDYPAVLMHLNATWPKR
VAQLPLKACLLEDFLDKSASGPGLAFVVFTETDLHMPGAPVWAMLFFGMLFTLGLSTMFG
TVEAVITPLLDVGVLPRWVPKEALTGLVCLVCFLSATCFTLQSGNYWLEIFDNFAASLNL
LMLAFLEVVGVVYVYGMKRFCDDIAWMTGRRPSPYWRLTWRVVSPLLLTIFVAYIILLFW
KPLRYKAWNPKYELFPSRQEKLYPGWARAACVLLSLLPVLWVPVAALAQLLTRRRRTWRD
RDARPDTDMRPDTDTRPDTDMRPDTDMR
|
External Links |
GenBank ID Protein
| 16550619 |
UniProtKB/Swiss-Prot ID
| Q96N87 |
UniProtKB/Swiss-Prot Entry Name
| S6A18_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AK055798 |
GeneCard ID
| SLC6A18 |
GenAtlas ID
| SLC6A18 |
HGNC ID
| HGNC:26441 |
References |
General References
| Not Available |