Identification
HMDB Protein ID CDBP04266
Secondary Accession Numbers Not Available
Name Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5
Description Not Available
Synonyms
  1. Solute carrier family 6 member 16
Gene Name SLC6A16
Protein Type Transporter
Biological Properties
General Function Involved in neurotransmitter:sodium symporter activity
Specific Function Not Available
GO Classification
Component
integral to plasma membrane
membrane
cell part
membrane part
intrinsic to membrane
integral to membrane
Function
neurotransmitter transporter activity
neurotransmitter:sodium symporter activity
transmembrane transporter activity
transporter activity
Process
establishment of localization
transport
neurotransmitter transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 19q13.1-q13.4
SNPs SLC6A16
Gene Sequence
>2211 bp
ATGAAGACAGAGGCCCAGCCTTCGACATCCTTGCTGGCAAACACCTCATGGACTGGCACA
GTGATTTCTGACAGTGTCCCAGGAAGTCAAACGTGGGAAGACAAGGGTTCATTGACCCGG
TCTGCAACATCTTGGACCTCAGAGGCCCAAGTTTCAGCAGCCCGGGTTGCAGAGGCTCAG
GCCAGGACCAGTCAGCCCAAGCAAATTTCTGTATTGGAGGCGTTAACTGCCTCAGCCCTG
AACCAGAAACCCACGCATGAGAAGGTGCAGATGACAGAGAAGAAAGAGAGTGAGGTCCTC
CTTGCCCGTCCGTTCTGGTCCAGCAAAACTGAGTATATTCTGGCTCAGGTGGGCTTCTCT
ATGAAGCCATCTTGTCTCTGGCGCTTTGCCTACCTGTGGCTTAACAGTGGAGGCTGCAGT
TTCGCTGCCATCTACATCTTCATGCTGTTCCTGGTCGGGGTTCCTCTTCTCTTCCTGGAG
ATGGCAGCTGGTCAGAGCATGCGTCAGGGTGGCATGGGTGTATGGAAGATCATTGCCCCC
TGGATTGGTGGTGTGGGGTATTCTAGCTTCATGGTGTGCTTCATCCTCGGCCTGTACTTC
AATGTGGTCAATTCCTGGATCATCTTCTACATGAGCCAGTCCTTCCAGTTTCCCGTTCCA
TGGGAGAAATGTCCCTTAACGATGAACTCTAGTGGCTTTGATCCTGAATGTGAACGGACA
ACACCCTCCATATACTTCTGGTACCAGCAGGCCTTGAAGGCCTCAGACAGAATCGAGGAT
GGCGGGTCACCAGTCTACAGTCTGGTCCTGCCCTTCTTTCTTTGCTGGTGTCTTGTTGGT
GCTTTCATGATCAATGGGCTCAAGTCCACTGGGAAGGTAATCTATGTCTTGGTACTGCTC
CCCTGTTTCATCATTGTCGGTTTCTTCATCCGGACTCTACTCCTGGAAGGGGCAAAATTT
GGCCTTCAACAGTTGGTGGTTGCCAAGATATCGGATGTGTACAATATGAGTGTGTGGTCT
CTAGCAGGGGGTCAAGTTTTGTCTAACACAGGCATAGGCCTTGGCTCCGTTGCCTCCTTA
GCCTCCTACATGCCCCAGTCCAACAACTGTCTCAGTGATGCCTTTCTCGTGTCTGTGATA
AACCTGCTCACTTTGTTGGTTTTCACATCTTTCAACTTCTGTGTCCTGGGCTTCTGGGCG
ACAGTCATCACACATCGCTGCTGTGAGAGGAATGCTGAAATACTTTTAAAGCTGATAAAC
CTAGGGAAACTGCCTCCTGATGCCAAGCCCCCTGTCAACCTGCTTTACAACCCAACCTCC
ATCTACAATGCCTGGCTCAGTGGCCTTCCCCAGCACATCAAAAGCATGGTTCTCCGCGAG
GTGACTGAGTGCAACATAGAGACTCAGTTTCTTAAGGCTAGCGAGGGCCCAAAGTTTGCA
TTCCTGTCCTTTGTTGAAGCCATGTCCTTCCTTCCTCCGTCTGTCTTCTGGTCTTTTATC
TTCTTCCTGATGTTGCTGGCCATGGGGCTGAGCAGCGCAATAGGGATTATGCAGGGCATC
ATTACTCCACTCCAGGACACCTTCTCTTTCTTCAGGAAACATACAAAGCTGCTCATAGTG
GGAGTCTTTTTGCTCATGTTCGTGTGCGGCCTCTTCTTCACTCGACCTTCAGGCAGCTAC
TTCATCAGACTGCTGAGTGACTACTGGATAGTCTTCCCCATCATCGTCGTTGTCGTATTT
GAAACCATGGCTGTATCCTGGGCCTATGGGGCCAGGAGGTTCCTTGCAGACCTGACGATC
CTGTTGGGCCACCCCATCTCTCCCATCTTTGGTTGGCTGTGGCCCCATCTGTGTCCAGTT
GTGCTGCTAATCATCTTTGTGACCATGATGGTTCATCTTTGTATGAAGCCGATCACCTAC
ATGTCCTGGGACTCAAGCACCTCAAAAGAGGTGCTTCGACCATACCCACCGTGGGCACTG
CTCTTGATGATCACCCTTTTTGCCATTGTCATCCTCCCCATCCCTGCATACTTTGTATAC
TGCCGCATACATAGGATTCCCTTCAGGCCCAAGAGCGGAGACGGGCCTATGACAGCCTCC
ACATCCCTACCCCTAAGTCACCAGCTAACACCCAGTAAAGAGGTTCAAAAGGAAGAAATT
CTACAAGTTGATGAAACAAAGTACCCATCAACTTGTAATGTGACTTCCTAA
Protein Properties
Number of Residues 736
Molecular Weight 82199.1
Theoretical pI 8.33
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["139-159", "177-197", "199-219", "264-284", "290-310", "338-358", "383-403", "496-516", "534-554", "568-588", "609-629", "659-679"]
Protein Sequence
>Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5
MKTEAQPSTSLLANTSWTGTVISDSVPGSQTWEDKGSLTRSATSWTSEAQVSAARVAEAQ
ARTSQPKQISVLEALTASALNQKPTHEKVQMTEKKESEVLLARPFWSSKTEYILAQVGFS
MKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMAAGQSMRQGGMGVWKIIAP
WIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWEKCPLTMNSSGFDPECERT
TPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLL
PCFIIVGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASL
ASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWATVITHRCCERNAEILLKLIN
LGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFA
FLSFVEAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFRKHTKLLIV
GVFLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTI
LLGHPISPIFGWLWPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVLRPYPPWAL
LLMITLFAIVILPIPAYFVYCRIHRIPFRPKSGDGPMTASTSLPLSHQLTPSKEVQKEEI
LQVDETKYPSTCNVTS
GenBank ID Protein 55749589
UniProtKB/Swiss-Prot ID Q9GZN6
UniProtKB/Swiss-Prot Entry Name S6A16_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_014037.2
GeneCard ID SLC6A16
GenAtlas ID SLC6A16
HGNC ID HGNC:13622
References
General References Not Available