Identification |
HMDB Protein ID
| CDBP04266 |
Secondary Accession Numbers
| Not Available |
Name
| Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5 |
Description
| Not Available |
Synonyms
|
- Solute carrier family 6 member 16
|
Gene Name
| SLC6A16 |
Protein Type
| Transporter |
Biological Properties |
General Function
| Involved in neurotransmitter:sodium symporter activity |
Specific Function
| Not Available |
GO Classification
|
Component |
integral to plasma membrane |
membrane |
cell part |
membrane part |
intrinsic to membrane |
integral to membrane |
Function |
neurotransmitter transporter activity |
neurotransmitter:sodium symporter activity |
transmembrane transporter activity |
transporter activity |
Process |
establishment of localization |
transport |
neurotransmitter transport |
|
Cellular Location
|
- Membrane
- Multi-pass membrane protein
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 19q13.1-q13.4 |
SNPs
| SLC6A16 |
Gene Sequence
|
>2211 bp
ATGAAGACAGAGGCCCAGCCTTCGACATCCTTGCTGGCAAACACCTCATGGACTGGCACA
GTGATTTCTGACAGTGTCCCAGGAAGTCAAACGTGGGAAGACAAGGGTTCATTGACCCGG
TCTGCAACATCTTGGACCTCAGAGGCCCAAGTTTCAGCAGCCCGGGTTGCAGAGGCTCAG
GCCAGGACCAGTCAGCCCAAGCAAATTTCTGTATTGGAGGCGTTAACTGCCTCAGCCCTG
AACCAGAAACCCACGCATGAGAAGGTGCAGATGACAGAGAAGAAAGAGAGTGAGGTCCTC
CTTGCCCGTCCGTTCTGGTCCAGCAAAACTGAGTATATTCTGGCTCAGGTGGGCTTCTCT
ATGAAGCCATCTTGTCTCTGGCGCTTTGCCTACCTGTGGCTTAACAGTGGAGGCTGCAGT
TTCGCTGCCATCTACATCTTCATGCTGTTCCTGGTCGGGGTTCCTCTTCTCTTCCTGGAG
ATGGCAGCTGGTCAGAGCATGCGTCAGGGTGGCATGGGTGTATGGAAGATCATTGCCCCC
TGGATTGGTGGTGTGGGGTATTCTAGCTTCATGGTGTGCTTCATCCTCGGCCTGTACTTC
AATGTGGTCAATTCCTGGATCATCTTCTACATGAGCCAGTCCTTCCAGTTTCCCGTTCCA
TGGGAGAAATGTCCCTTAACGATGAACTCTAGTGGCTTTGATCCTGAATGTGAACGGACA
ACACCCTCCATATACTTCTGGTACCAGCAGGCCTTGAAGGCCTCAGACAGAATCGAGGAT
GGCGGGTCACCAGTCTACAGTCTGGTCCTGCCCTTCTTTCTTTGCTGGTGTCTTGTTGGT
GCTTTCATGATCAATGGGCTCAAGTCCACTGGGAAGGTAATCTATGTCTTGGTACTGCTC
CCCTGTTTCATCATTGTCGGTTTCTTCATCCGGACTCTACTCCTGGAAGGGGCAAAATTT
GGCCTTCAACAGTTGGTGGTTGCCAAGATATCGGATGTGTACAATATGAGTGTGTGGTCT
CTAGCAGGGGGTCAAGTTTTGTCTAACACAGGCATAGGCCTTGGCTCCGTTGCCTCCTTA
GCCTCCTACATGCCCCAGTCCAACAACTGTCTCAGTGATGCCTTTCTCGTGTCTGTGATA
AACCTGCTCACTTTGTTGGTTTTCACATCTTTCAACTTCTGTGTCCTGGGCTTCTGGGCG
ACAGTCATCACACATCGCTGCTGTGAGAGGAATGCTGAAATACTTTTAAAGCTGATAAAC
CTAGGGAAACTGCCTCCTGATGCCAAGCCCCCTGTCAACCTGCTTTACAACCCAACCTCC
ATCTACAATGCCTGGCTCAGTGGCCTTCCCCAGCACATCAAAAGCATGGTTCTCCGCGAG
GTGACTGAGTGCAACATAGAGACTCAGTTTCTTAAGGCTAGCGAGGGCCCAAAGTTTGCA
TTCCTGTCCTTTGTTGAAGCCATGTCCTTCCTTCCTCCGTCTGTCTTCTGGTCTTTTATC
TTCTTCCTGATGTTGCTGGCCATGGGGCTGAGCAGCGCAATAGGGATTATGCAGGGCATC
ATTACTCCACTCCAGGACACCTTCTCTTTCTTCAGGAAACATACAAAGCTGCTCATAGTG
GGAGTCTTTTTGCTCATGTTCGTGTGCGGCCTCTTCTTCACTCGACCTTCAGGCAGCTAC
TTCATCAGACTGCTGAGTGACTACTGGATAGTCTTCCCCATCATCGTCGTTGTCGTATTT
GAAACCATGGCTGTATCCTGGGCCTATGGGGCCAGGAGGTTCCTTGCAGACCTGACGATC
CTGTTGGGCCACCCCATCTCTCCCATCTTTGGTTGGCTGTGGCCCCATCTGTGTCCAGTT
GTGCTGCTAATCATCTTTGTGACCATGATGGTTCATCTTTGTATGAAGCCGATCACCTAC
ATGTCCTGGGACTCAAGCACCTCAAAAGAGGTGCTTCGACCATACCCACCGTGGGCACTG
CTCTTGATGATCACCCTTTTTGCCATTGTCATCCTCCCCATCCCTGCATACTTTGTATAC
TGCCGCATACATAGGATTCCCTTCAGGCCCAAGAGCGGAGACGGGCCTATGACAGCCTCC
ACATCCCTACCCCTAAGTCACCAGCTAACACCCAGTAAAGAGGTTCAAAAGGAAGAAATT
CTACAAGTTGATGAAACAAAGTACCCATCAACTTGTAATGTGACTTCCTAA
|
Protein Properties |
Number of Residues
| 736 |
Molecular Weight
| 82199.1 |
Theoretical pI
| 8.33 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
- ["139-159", "177-197", "199-219", "264-284", "290-310", "338-358", "383-403", "496-516", "534-554", "568-588", "609-629", "659-679"]
|
Protein Sequence
|
>Orphan sodium- and chloride-dependent neurotransmitter transporter NTT5
MKTEAQPSTSLLANTSWTGTVISDSVPGSQTWEDKGSLTRSATSWTSEAQVSAARVAEAQ
ARTSQPKQISVLEALTASALNQKPTHEKVQMTEKKESEVLLARPFWSSKTEYILAQVGFS
MKPSCLWRFAYLWLNSGGCSFAAIYIFMLFLVGVPLLFLEMAAGQSMRQGGMGVWKIIAP
WIGGVGYSSFMVCFILGLYFNVVNSWIIFYMSQSFQFPVPWEKCPLTMNSSGFDPECERT
TPSIYFWYQQALKASDRIEDGGSPVYSLVLPFFLCWCLVGAFMINGLKSTGKVIYVLVLL
PCFIIVGFFIRTLLLEGAKFGLQQLVVAKISDVYNMSVWSLAGGQVLSNTGIGLGSVASL
ASYMPQSNNCLSDAFLVSVINLLTLLVFTSFNFCVLGFWATVITHRCCERNAEILLKLIN
LGKLPPDAKPPVNLLYNPTSIYNAWLSGLPQHIKSMVLREVTECNIETQFLKASEGPKFA
FLSFVEAMSFLPPSVFWSFIFFLMLLAMGLSSAIGIMQGIITPLQDTFSFFRKHTKLLIV
GVFLLMFVCGLFFTRPSGSYFIRLLSDYWIVFPIIVVVVFETMAVSWAYGARRFLADLTI
LLGHPISPIFGWLWPHLCPVVLLIIFVTMMVHLCMKPITYMSWDSSTSKEVLRPYPPWAL
LLMITLFAIVILPIPAYFVYCRIHRIPFRPKSGDGPMTASTSLPLSHQLTPSKEVQKEEI
LQVDETKYPSTCNVTS
|
External Links |
GenBank ID Protein
| 55749589 |
UniProtKB/Swiss-Prot ID
| Q9GZN6 |
UniProtKB/Swiss-Prot Entry Name
| S6A16_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_014037.2 |
GeneCard ID
| SLC6A16 |
GenAtlas ID
| SLC6A16 |
HGNC ID
| HGNC:13622 |
References |
General References
| Not Available |