Showing Protein Amiloride-sensitive cation channel 4 (CDBP04247)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 0 compounds
Identification
HMDB Protein ID CDBP04247
Secondary Accession Numbers Not Available
Name Amiloride-sensitive cation channel 4
Description Not Available
Synonyms
  1. ASIC4
  2. Acid-sensing ion channel 4
  3. Amiloride-sensitive cation channel 4, pituitary
Gene Name ACCN4
Protein Type Transporter
Biological Properties
General Function Involved in sodium channel activity
Specific Function Probable cation channel with high affinity for sodium. In vitro, has no proton-gated channel activity
GO Classification
Component
membrane
cell part
Function
transmembrane transporter activity
substrate-specific transmembrane transporter activity
ion transmembrane transporter activity
sodium channel activity
transporter activity
ion channel activity
cation channel activity
Process
monovalent inorganic cation transport
ion transport
cation transport
sodium ion transport
establishment of localization
transport
Cellular Location
  1. Membrane
  2. Multi-pass membrane protein
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q35
SNPs ACCN4
Gene Sequence 
>1944 bp
ATGCTGAGCGGAGCGGCTGGGGCTGCGCGGCGTGGCGGAGCAGCGCTCGCTCCCTCGCTC
ACTCGCTCGCTCGCAGGGACACACGCAGGGGCTGACAGCTGTGCTGGTGCTGATAAGGGA
AGCCACAAGGAGACGATCGAGGAGAGAGACAAGCGGCAGCAGAGGCAGCAGCGGCAGAGG
CAGCACCAGGGCTGCGGAGCTGCTGGGAGTGGGAGTGACTCCCCCACCTCGGGCCCCCAC
CCTGTCCCTGTCCTCTTCCCGCTTGCCCTGAGTTTAGAAGAGCAGCCGCTGCCACCACTG
CCACTCGGGAGGGCACCAGGGCTGCTGGCTAGGGAGGGACAGGGCAGGGAGGCTCTGGCC
AGTCCCAGCAGCCGGGGACAGATGCCGATCGAGATTGTGTGCAAAATCAAATTTGCTGAG
GAGGATGCGAAACCCAAGGAGAAGGAGGCAGGGGATGAGCAGAGCCTCCTCGGGGCTGTT
GCCCCTGGAGCAGCCCCCCGAGACCTGGCCACCTTTGCCAGCACCAGCACCCTGCATGGA
CTGGGCCGGGCCTGTGGCCCAGGCCCCCACGGACTGCGCAGAACCCTGTGGGCACTGGCC
CTACTCACCTCGCTGGCTGCCTTCCTGTACCAGGCGGCTGGCCTGGCCCGGGGCTACCTG
ACCCGGCCTCACCTGGTGGCAATGGACCCCGCTGCCCCAGCCCCAGTGGCGGGCTTCCCG
GCTGTCACCCTCTGCAATATCAACCGCTTCCGGCATTCGGCACTCAGCGATGCCGACATC
TTCCACCTGGCCAATCTGACAGGGCTGCCCCCCAAAGACCGGGATGGGCACCGTGCGGCT
GGCCTGCGCTACCCAGAGCCTGACATGGTAGACATCCTCAACCGCACTGGCCACCAGCTC
GCCGACATGCTTAAGAGCTGCAACTTCAGTGGGCATCACTGCTCCGCCAGCAACTTCTCT
GTGGTCTATACTCGCTATGGGAAGTGTTACACCTTCAACGCGGACCCGCGGAGCTCGCTG
CCCAGCCGGGCAGGGGGCATGGGCAGTGGCCTGGAGATCATGCTGGACATCCAGCAGGAG
GAGTACCTGCCCATCTGGAGGGAGACAAATGAGACGTCGTTTGAGGCAGGTATTCGGGTG
CAGATCCACAGCCAGGAGGAGCCGCCCTACATCCACCAGCTGGGGTTCGGGGTGTCCCCA
GGCTTCCAGACCTTTGTGTCCTGCCAGGAACAGCGGCTGACCTACCTGCCCCAGCCCTGG
GGCAACTGCCGCGCAGAGAGTGAGCTCAGGGAGCCTGAGCTTCAGGGCTACTCGGCCTAC
AGTGTGTCTGCCTGCCGGCTGCGCTGTGAAAAGGAGGCCGTGCTTCAGCGCTGCCACTGC
CGGATGGTGCACATGCCAGACTCCCTGGGTGGGGGCCCTGAGGGCCCGTGCTTCTGCCCC
ACCCCCTGCAACCTGACACGCTATGGGAAAGAGATCTCCATGGTCAGGATCCCCAACAGG
GGCTCAGCCCGGTACCTGGCGAGGAAGTACAACCGCAACGAGACCTACATACGGGAGAAC
TTCCTGGTCCTAGATGTCTTCTTTGAGGCCCTGACCTCTGAAGCCATGGAGCAGCGAGCA
GCCTATGGCCTGTCAGCCCTGCTGGGAGACCTCGGGGGACAGATGGGCCTGTTCATTGGG
GCCAGCATCCTCACGTTGCTGGAGATCCTCGACTACATCTATGAGGTGTCCTGGGATCGA
CTGAAGCGGGTATGGAGGCGTCCCAAGACCCCCCTGCGGACCTCCACTGGGGGCATCTCC
ACTTTGGGGCTTCAGGAGCTGAAGGAACAGAGTCCCTGCCCGAGCCTGGGCCGAGCGGAG
GGTGGGGGGGTCAGCAGTCTGCTCCCCAATCACCACCACCCCCACGGTCCCCCAGGAGGT
CTCTTTGAAGATTTTGCTTGCTAG
Protein Properties
Number of Residues 647
Molecular Weight 70103.9
Theoretical pI 7.87
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["196-216", "547-567"]
Protein Sequence 
>Amiloride-sensitive cation channel 4
MLSGAAGAARRGGAALAPSLTRSLAGTHAGADSCAGADKGSHKETIEERDKRQQRQQRQR
QHQGCGAAGSGSDSPTSGPHPVPVLFPLALSLEEQPLPPLPLGRAPGLLAREGQGREALA
SPSSRGQMPIEIVCKIKFAEEDAKPKEKEAGDEQSLLGAVAPGAAPRDLATFASTSTLHG
LGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVAMDPAAPAPVAGFP
AVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHRAAGLRYPEPDMVDILNRTGHQL
ADMLKSCNFSGHHCSASNFSVVYTRYGKCYTFNADPRSSLPSRAGGMGSGLEIMLDIQQE
EYLPIWRETNETSFEAGIRVQIHSQEEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPW
GNCRAESELREPELQGYSAYSVSACRLRCEKEAVLQRCHCRMVHMPDSLGGGPEGPCFCP
TPCNLTRYGKEISMVRIPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQRA
AYGLSALLGDLGGQMGLFIGASILTLLEILDYIYEVSWDRLKRVWRRPKTPLRTSTGGIS
TLGLQELKEQSPCPSRGRVEGGGVSSLLPNHHHPHGPPGGLFEDFAC
GenBank ID Protein 14714604
UniProtKB/Swiss-Prot ID Q96FT7
UniProtKB/Swiss-Prot Entry Name ACCN4_HUMAN
PDB IDs Not Available
GenBank Gene ID BC010439
GeneCard ID ACCN4
GenAtlas ID ACCN4
HGNC ID HGNC:21263
References
General References Not Available