Cannabis Compound Database: Showing Protein tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial (CDBP04240)

Identification Biological properties Gene properties Protein properties External links References XML Show 2 compounds

Identification

HMDB Protein ID

CDBP04240

Secondary Accession Numbers

Not Available

Name

tRNA (adenine(58)-N(1))-methyltransferase, mitochondrial

Description

Not Available

Synonyms

Not Available

Gene Name

TRMT61B

Protein Type

Enzyme

Biological Properties

General Function

Involved in tRNA (adenine-N1-)-methyltransferase activity

Specific Function

Methyltransferase that catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in various tRNAs in mitochondrion, including tRNA(Leu) (decephering codons UUA or UUG), tRNA(Lys) and tRNA(Ser) (decephering codons UCA, UCU, UCG or UCC).

GO Classification

Biological Process
mitochondrial tRNA methylation
protein homooligomerization
Cellular Component
tRNA (m1A) methyltransferase complex
mitochondrion
Function
catalytic activity
transferase activity
rna methyltransferase activity
trna methyltransferase activity
trna (adenine) methyltransferase activity
trna (adenine-n1-)-methyltransferase activity
transferase activity, transferring one-carbon groups
methyltransferase activity
Molecular Function
tRNA (adenine-N1-)-methyltransferase activity
Process
rna metabolic process
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
rna modification
rna methylation
trna methylation

Cellular Location

Not Available

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

2p23.2

SNPs

TRMT61B

Gene Sequence

>1434 bp
ATGCTAATGGCATGGTGCCGCGGTCCTGTCTTGCTGTGCCTGCGGCAGGGGCTCGGAACC
AATTCATTCCTGCACGGCCTGGGGCAGGAGCCCTTCGAGGGAGCTCGGTCACTGTGTTGC
AGGTCCTCGCCTAGAGACCTGCGAGATGGAGAAAGAGAGCACGAGGCGGCACAAAGGAAA
GCCCCAGGAGCAGAGTCTTGCCCATCTCTCCCTCTGAGCATCTCGGACATTGGGACTGGA
TGTCTTTCGTCACTGGAAAACCTCAGACTGCCGACGCTGCGGGAAGAGTCATCCCCTCGA
GAGCTCGAGGACTCGAGCGGAGACCAGGGCCGGTGCGGTCCCACACACCAGGGATCCGAG
GATCCTTCGATGCTCTCGCAGGCCCAGTCCGCTACCGAGGTCGAAGAGCGTCACGTCTCC
CCTTCTTGTTCAACTTCCAGAGAGAGACCCTTTCAGGCTGGGGAACTGATTTTAGCTGAG
ACTGGGGAGGGAGAAACAAAATTTAAGAAATTATTTAGGTTGAACAACTTCGGACTCTTA
AATAGTAACTGGGGGGCAGTCCCGTTCGGCAAGATCGTGGGGAAGTTCCCCGGCCAGATA
CTGAGGAGTTCCTTCGGTAAGCAGTACATGCTGAGGAGGCCAGCCTTGGAAGACTATGTA
GTATTGATGAAAAGAGGGACTGCCATAACATTCCCAAAGGATATTAATATGATTCTCTCA
ATGATGGATATCAACCCAGGTGATACTGTTTTGGAAGCTGGCTCAGGCTCTGGTGGAATG
AGCTTATTTTTATCCAAAGCAGTTGGATCACAAGGACGAGTCATAAGTTTTGAGGTACGA
AAAGACCACCATGATCTGGCTAAGAAGAATTACAAACACTGGCGTGATTCATGGAAATTA
AGTCATGTAGAAGAGTGGCCAGACAATGTGGATTTTATTCATAAGGACATTTCAGGAGCA
ACCGAAGACATAAAATCTTTAACATTTGACGCAGTAGCTTTGGATATGTTAAATCCTCAT
GTTACTTTGCCTGTTTTTTACCCACATCTTAAGCATGGTGGTGTATGTGCTGTATATGTA
GTAAACATCACACAGGTTATTGAACTTTTAGATGGAATTCGCACCTGTGAACTTGCTCTT
TCATGTGAAAAGATAAGCGAGGTCATTGTCAGAGATTGGTTGGTTTGCCTTGCAAAACAG
AAAAATGGAATTTTAGCTCAAAAAGTAGAATCTAAAATCAACACAGATGTACAACTAGAT
TCTCAAGAGAAAATTGGAGTTAAAGGTGAGCTGTTTCAAGAGGATGACCATGAAGAATCG
CATTCTGATTTTCCATATGGATCATTTCCCTATGTTGCTAGACCAGTACACTGGCAACCT
GGTCATACAGCTTTTCTTGTCAAGTTGAGGAAGGTCAAACCACAACTTAACTGA

Protein Properties

Number of Residues

477

Molecular Weight

52964.87

Theoretical pI

6.626

Pfam Domain Function

GCD14 (PF08704 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Potential tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61B
MLMAWCRGPVLLCLRQGLGTNSFLHGLGQEPFEGARSLCCRSSPRDLRDGEREHEAAQRK
APGAESCPSLPLSISDIGTGCLSSLENLRLPTLREESSPRELEDSSGDQGRCGPTHQGSE
DPSMLSQAQSATEVEERHVSPSCSTSRERPFQAGELILAETGEGETKFKKLFRLNNFGLL
NSNWGAVPFGKIVGKFPGQILRSSFGKQYMLRRPALEDYVVLMKRGTAITFPKDINMILS
MMDINPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKKNYKHWRDSWKL
SHVEEWPDNVDFIHKDISGATEDIKSLTFDAVALDMLNPHVTLPVFYPHLKHGGVCAVYV
VNITQVIELLDGIRTCELALSCEKISEVIVRDWLVCLAKQKNGILAQKVESKINTDVQLD
SQEKIGVKGELFQEDDHEESHSDFPYGSFPYVARPVHWQPGHTAFLVKLRKVKPQLN

External Links

GenBank ID Protein

62988627

UniProtKB/Swiss-Prot ID

Q9BVS5

UniProtKB/Swiss-Prot Entry Name

TR61B_HUMAN

PDB IDs