Identification |
HMDB Protein ID
| CDBP04238 |
Secondary Accession Numbers
| Not Available |
Name
| tRNA (adenine(58)-N(1))-methyltransferase catalytic subunit TRMT61A |
Description
| Not Available |
Synonyms
|
- tRNA(m1A58)-methyltransferase subunit TRMT61A
- tRNA(m1A58)MTase subunit TRMT61A
|
Gene Name
| TRMT61A |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in tRNA (adenine-N1-)-methyltransferase activity |
Specific Function
| Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA.
|
GO Classification
|
Cellular Component |
tRNA (m1A) methyltransferase complex |
nucleus |
Function |
catalytic activity |
transferase activity |
rna methyltransferase activity |
trna methyltransferase activity |
trna (adenine) methyltransferase activity |
trna (adenine-n1-)-methyltransferase activity |
transferase activity, transferring one-carbon groups |
methyltransferase activity |
Molecular Function |
tRNA (adenine-N1-)-methyltransferase activity |
Process |
rna methylation |
trna methylation |
rna metabolic process |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
rna modification |
|
Cellular Location
|
- Nucleus
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| 14 |
Locus
| 14q32 |
SNPs
| TRMT61A |
Gene Sequence
|
>870 bp
ATGAGCTTCGTGGCATACGAGGAGCTGATCAAGGAGGGTGACACGGCCATCCTGTCACTG
GGCCATGGTGCAATGGTGGCAGTGCGTGTGCAGCGTGGGGCACAGACCCAGACCCGGCAT
GGTGTCCTGCGGCACTCAGTTGACCTTATCGGCCGCCCCTTCGGCTCCAAGGTGACGTGC
GGCCGAGGTGGCTGGGTGTATGTGCTGCACCCCACGCCCGAGCTCTGGACGCTGAACCTG
CCGCACCGCACGCAGATCCTCTACTCCACAGACATCGCCCTCATCACCATGATGTTGGAG
CTTCGGCCCGGCTCTGTGGTCTGTGAGTCTGGCACCGGCAGTGGCTCTGTGTCCCACGCC
ATCATCCGCACCATTGCACCCACGGGTCACCTGCACACGGTGGAGTTCCACCAGCAGCGG
GCAGAGAAGGCCCGGGAGGAGTTCCAGGAGCACCGTGTGGGCCGCTGGGTGACTGTGCGC
ACCCAGGACGTGTGCCGCAGTGGCTTTGGCGTGAGCCACGTGGCCGACGCCGTCTTCCTG
GACATCCCATCACCCTGGGAGGCCGTGGGCCACGCCTGGGACGCCCTCAAGGTCGAAGGC
GGGCGCTTCTGCTCCTTCTCACCGTGCATCGAGCAGGTGCAACGCACATGCCAGGCGCTG
GCAGCGCGCGGCTTCTCAGAGCTGAGCACCCTGGAGGTGCTGCCACAGGTCTACAACGTG
CGCACTGTCAGCCTGCCACCGCCCGACCTGGGCACAGGCACAGATGGCCCTGCCGGCTCC
GACACCAGCCCCTTCCGCAGCGGCACGCCCATGAAGGAGGCCGTGGGCCACACCGGCTAC
CTGACCTTCGCCACCAAGACCCCAGGCTAG
|
Protein Properties |
Number of Residues
| 289 |
Molecular Weight
| 31381.48 |
Theoretical pI
| 7.358 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>tRNA (adenine-N(1)-)-methyltransferase catalytic subunit TRMT61A
MSFVAYEELIKEGDTAILSLGHGAMVAVRVQRGAQTQTRHGVLRHSVDLIGRPFGSKVTC
GRGGWVYVLHPTPELWTLNLPHRTQILYSTDIALITMMLELRPGSVVCESGTGSGSVSHA
IIRTIAPTGHLHTVEFHQQRAEKAREEFQEHRVGRWVTVRTQDVCRSGFGVSHVADAVFL
DIPSPWEAVGHAWDALKVEGGRFCSFSPCIEQVQRTCQALAARGFSELSTLEVLPQVYNV
RTVSLPPPDLGTGTDGPAGSDTSPFRSGTPMKEAVGHTGYLTFATKTPG
|
External Links |
GenBank ID Protein
| 123173772 |
UniProtKB/Swiss-Prot ID
| Q96FX7 |
UniProtKB/Swiss-Prot Entry Name
| TRM61_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_152307.2 |
GeneCard ID
| TRMT61A |
GenAtlas ID
| TRMT61A |
HGNC ID
| HGNC:23790 |
References |
General References
| Not Available |