Identification |
HMDB Protein ID
| CDBP04222 |
Secondary Accession Numbers
| Not Available |
Name
| Putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase |
Description
| Not Available |
Synonyms
|
- Protein ftsJ homolog 1
- rRNA (uridine-2'-O-)-methyltransferase
- 2'-O-ribose RNA methyltransferase TRM7 homolog
|
Gene Name
| FTSJ1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in methyltransferase activity |
Specific Function
| Methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop of substrate tRNAs (By similarity).
|
GO Classification
|
Biological Process |
RNA methylation |
rRNA processing |
Function |
binding |
catalytic activity |
transferase activity |
nucleic acid binding |
transferase activity, transferring one-carbon groups |
methyltransferase activity |
Molecular Function |
methyltransferase activity |
Process |
one-carbon metabolic process |
rrna metabolic process |
rrna processing |
methylation |
rrna modification |
rrna methylation |
rna metabolic process |
ncrna metabolic process |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
cellular metabolic process |
|
Cellular Location
|
- Cytoplasmic
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| X |
Locus
| Xp11.23 |
SNPs
| FTSJ1 |
Gene Sequence
|
>990 bp
ATGGGACGGACGTCAAAGGACAAGCGGGATGTCTACTACCGCCTGGCCAAGGAGAATGGC
TGGCGTGCTCGCAGCGCCTTCAAACTGCTACAACTGGATAAGGAATTCCAACTCTTCCAA
GGCGTGACACGGGCAGTTGACCTGTGTGCAGCCCCAGGCAGCTGGAGCCAGGTGCTGAGC
CAGAAGATCGGGGGCCAAGGGTCCGGCCACGTGGTGGCTGTGGACCTGCAGGCTATGGCT
CCACTACCAGGTGTGGTACAGATCCAGGGGGACATCACCCAGCTGTCCACTGCCAAGGAG
ATCATCCAGCACTTTAAGGGCTGCCCTGCGGACCTAGTGGTGTGTGACGGGGCTCCTGAT
GTAACCGGTCTCCATGATGTTGATGAGTATATGCAGGCCCAGCTCCTCCTAGCTGCTCTG
AACATTGCTACACATGTCCTGAAGCCAGGGGGCTGCTTTGTGGCCAAGATATTCCGAGGC
CGGGATGTGACGCTCCTCTACAGCCAGCTGCAGGTCTTCTTCTCCAGCGTGCTGTGTGCC
AAGCCCAGGAGCAGCCGGAACTCTAGCATCGAGGCCTTCGCTGTCTGTCAGGGCTATGAC
CCTCCCGAGGGCTTCATCCCGGACCTGAGCAAACCCCTGCTGGACCATTCTTACGACCCA
GATTTCAACCAGCTGGATGGTCCCACCCGCATCATTGTGCCTTTTGTGACCTGTGGGGAC
CTGAGCTCCTATGATTCGGACCGCAGTTACCCACTGGACCTAGAGGGCGGCTCAGAGTAC
AAGTACACTCCACCCACACAGCCCCCCATCTCGCCACCATACCAGGAGGCCTGCACGTTG
AAGAGGAAGGGGCAGCTGGCCAAGGAGATCCGCCCCCAGGACTGCCCCATCAGCAGAGTG
GACACGTTTCCCCAGCCCCTGGCCGCCCCTCAGTGCCACACCCTGCTGGCCCCTGAGATG
GAAGACAATGAAATGAGTTGTTCACCTTAA
|
Protein Properties |
Number of Residues
| 329 |
Molecular Weight
| 36078.76 |
Theoretical pI
| 5.695 |
Pfam Domain Function
|
|
Signals
|
Not Available
|
Transmembrane Regions
|
Not Available
|
Protein Sequence
|
>Putative ribosomal RNA methyltransferase 1
MGRTSKDKRDVYYRLAKENGWRARSAFKLLQLDKEFQLFQGVTRAVDLCAAPGSWSQVLS
QKIGGQGSGHVVAVDLQAMAPLPGVVQIQGDITQLSTAKEIIQHFKGCPADLVVCDGAPD
VTGLHDVDEYMQAQLLLAALNIATHVLKPGGCFVAKIFRGRDVTLLYSQLQVFFSSVLCA
KPRSSRNSSIEAFAVCQGYDPPEGFIPDLSKPLLDHSYDPDFNQLDGPTRIIVPFVTCGD
LSSYDSDRSYPLDLEGGSEYKYTPPTQPPISPPYQEACTLKRKGQLAKEIRPQDCPISRV
DTFPQPLAAPQCHTLLAPEMEDNEMSCSP
|
External Links |
GenBank ID Protein
| 7110661 |
UniProtKB/Swiss-Prot ID
| Q9UET6 |
UniProtKB/Swiss-Prot Entry Name
| RRMJ1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_012280.2 |
GeneCard ID
| FTSJ1 |
GenAtlas ID
| FTSJ1 |
HGNC ID
| HGNC:13254 |
References |
General References
| Not Available |