Identification |
HMDB Protein ID
| CDBP04206 |
Secondary Accession Numbers
| Not Available |
Name
| rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| FBLL1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in RNA binding |
Specific Function
| Involved in pre-rRNA processing. Utilizes the methyl donor S-adenosyl-L-methionine to catalyze the site-specific 2'- hydroxyl methylation of ribose moieties in pre-ribosomal RNA |
GO Classification
|
Function |
transferase activity, transferring one-carbon groups |
methyltransferase activity |
rna binding |
binding |
catalytic activity |
transferase activity |
nucleic acid binding |
Process |
rna metabolic process |
ncrna metabolic process |
trna metabolic process |
trna processing |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
rrna metabolic process |
rrna processing |
|
Cellular Location
|
- Nucleus
- nucleolus
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:5 |
Locus
| 5q34 |
SNPs
| FBLL1 |
Gene Sequence
|
Not Available
|
Protein Properties |
Number of Residues
| 333 |
Molecular Weight
| 34675.1 |
Theoretical pI
| 10.95 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>rRNA/tRNA 2'-O-methyltransferase fibrillarin-like protein 1
MKSAASSRGGGGGGRGGGGWGSWGGGRGGGGGAGKGGGGDGGGQGGKGGFGARARGFGGG
GRGRGRGGGDGKDRGGGGQRRGGVAKSKSRRRKGAMVVSVEPHRHEGVFIYRGAEDALVT
LNMVPGQSVYGERRVTVTEGGVKQEYRTWNPFRSKLAAAILGGVDQIHIKPKSKVLYLGA
ASGTTVSHVSDIIGPDGLVYAVEFSHRAGRDLVNVAKKRTNIIPVLEDARHPLKYRMLIG
MVDVIFADVAQPDQSRIVALNAHTFLRNGGHFLISIKANCIDSTASAEAVFASEVRKLQQ
ENLKPQEQLTLEPYERDHAVVVGVYRPLPKSSS
|
External Links |
GenBank ID Protein
| Not Available |
UniProtKB/Swiss-Prot ID
| A6NHQ2 |
UniProtKB/Swiss-Prot Entry Name
| FBLL1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| Not Available |
GeneCard ID
| FBLL1 |
GenAtlas ID
| FBLL1 |
HGNC ID
| HGNC:35458 |
References |
General References
| Not Available |