Identification
HMDB Protein ID CDBP04203
Secondary Accession Numbers Not Available
Name CDK5 regulatory subunit-associated protein 1
Description Not Available
Synonyms
  1. CDK5 activator-binding protein C42
Gene Name CDK5RAP1
Protein Type Enzyme
Biological Properties
General Function Involved in catalytic activity
Specific Function Specifically inhibits CDK5 activation by CDK5R1
GO Classification
Component
cell part
intracellular part
cytoplasm
Function
transferase activity
metal cluster binding
iron-sulfur cluster binding
4 iron, 4 sulfur cluster binding
binding
catalytic activity
Process
rna metabolic process
ncrna metabolic process
trna metabolic process
trna processing
metabolic process
macromolecule metabolic process
cellular macromolecule metabolic process
rna modification
trna modification
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 20pter-q11.23
SNPs CDK5RAP1
Gene Sequence
>3606 bp
ATGCACCCTTTACAGTGTGTCCTCCAAGTGCAGAGGTCTCTGGGGTGGGGACCATTGGCC
TCTGTGTCTTGGCTGTCGCTGAGGATGTGCAGGGCACACAGCAGTCTCTCTAGTACCATG
TGTCCCAGTCCAGAGAGGCAGGAGGATGGAGCTCGGAAGGATTTCAGCTCCAGGCTGGCT
GCTGGACCGACTTTTCAACATTTTTTAAAAAGTGCCTCAGCTCCTCAGGAGAAGCTGTCT
TCAGAAGTGGAAGACCCACCTCCCTATCTCATGATGGATGAACTTCTTGGAAGGCAGAGA
AAAGTCTACCTCGAGACCTATGGCTGCCAGATGAATGTGAATGACACAGAGATAGCCTGG
TCCATCTTACAGAAGAGTGGCTACCTGCGGACCAGTAACCTCCAAGAGGCAGATGTGATT
CTCCTTGTCACATGCTCTATCAGGGAGAAGGCTGAGCAGACCATCTGGAACCGTTTACAT
CAGCTTAAAGCCTTGAAGACAAGGCGGCCCCGCTCCCGGGTTCCTCTGAGGATTGGAATT
CTAGGCTGCATGGCTGAGAGGTTGAAGGAGGAGATTCTCAACAGAGAGAAAATGGTAGAT
ATTTTGGCTGGTCCTGATGCCTACCGGGACCTTCCCCGGCTGCTGGCTGTTGCTGAGTCG
GGCCAGCAAGCTGCCAACGTGCTGCTCTCTCTGGACGAGACCTATGCTGATGTCATGCCA
GTCCAGACAAGCGCCAGTGCCACGTCTGCCTTTGTGTCAATCATGCGAGGCTGTGACAAC
ATGTGTAGCTACTGCATTGTTCCTTTCACCCGGGGCAGGGAGAGGAGTCGGCCTATTGCC
TCCATTCTAGAGGAAGTGAAGAAGCTTTCTGAGCAGGTGTTCCTCCCACCTCGGCCTCCC
AAAGTGTTGGGATTACAGGGGCTGAAAGAAGTGACACTTCTTGGTCAGAATGTTAATAGT
TTTCGGGACAATTCGGAGGTCCAGTTCAACAGTGCAGTGCCTACCAATCTCAGTCGTGGC
TTTACCACCAACTATAAAACCAAGCAAGGAGGACTTCGTTTTGCTCATCTTCTGGATCAG
GTCTCCAGAGTAGATCCTGAAATGAGGATCCGTTTTACCTCTCCCCACCCCAAGGATTTT
CCTGATGAGGTTCTGCAGCTGATTCATGAGAGAGATAACATCTGTAAACAGATCCACCTG
CCAGCCCAGAGTGGAAGCAGCCGTGTGTTGGAGGCCATGCGGAGGGGATATTCAAGAGAA
GCTTATGTGGAGTTAGTTCACCATATTAGAGAATCTATTCCAGGTGTGAGCCTCAGCAGC
GATTTCATTGCTGGCTTTTGTGGTGAGACGGAGGAAGATCACGTCCAGACAGTCTCTTTG
CTCCGGGAAGTTCAGTACAACATGGGCTTCCTCTTTGCCTACAGCATGAGACAGAAGACA
CGGGCATATCATAGGCTGAAGGATGATGTCCCGGAAGAGGTAAAATTAAGGCGTTTGGAG
GAACTCATCACTATCTTCCGAGAAGAAGCAACAAAAGCCAATCAGACCTCTGTGGGCTGT
ACCCAGTTGGTGCTAGTGGAAGGGCTCAGTAAACGCTCTGCCACTGACCTGTGTGGCAGG
AATGATGGAAACCTTAAGGTGATCTTCCCTGATGCAGAGATGGAGGATGTCAATAACCCT
GGGCTCAGGGTCAGAGCCCAGCCTGGGGACTATGTGCTGGTGAAGATCACCTCAGCCAGT
TCTCAGACACTTAGGGGACATGTTCTCTGCAGGACCACTCTGAGGGACTCTTCTGCATAT
TGCTGA
Protein Properties
Number of Residues 601
Molecular Weight 67687.9
Theoretical pI 8.28
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>CDK5 regulatory subunit-associated protein 1
MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLA
AGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAW
SILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGI
LGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMP
VQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQVFLPPRPP
KVLGLQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQ
VSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSRE
AYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKT
RAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGR
NDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAY
C
GenBank ID Protein 56205140
UniProtKB/Swiss-Prot ID Q96SZ6
UniProtKB/Swiss-Prot Entry Name CK5P1_HUMAN
PDB IDs Not Available
GenBank Gene ID AL355392
GeneCard ID CDK5RAP1
GenAtlas ID CDK5RAP1
HGNC ID HGNC:15880
References
General References Not Available