Identification |
HMDB Protein ID
| CDBP04203 |
Secondary Accession Numbers
| Not Available |
Name
| CDK5 regulatory subunit-associated protein 1 |
Description
| Not Available |
Synonyms
|
- CDK5 activator-binding protein C42
|
Gene Name
| CDK5RAP1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in catalytic activity |
Specific Function
| Specifically inhibits CDK5 activation by CDK5R1 |
GO Classification
|
Component |
cell part |
intracellular part |
cytoplasm |
Function |
transferase activity |
metal cluster binding |
iron-sulfur cluster binding |
4 iron, 4 sulfur cluster binding |
binding |
catalytic activity |
Process |
rna metabolic process |
ncrna metabolic process |
trna metabolic process |
trna processing |
metabolic process |
macromolecule metabolic process |
cellular macromolecule metabolic process |
rna modification |
trna modification |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:2 |
Locus
| 20pter-q11.23 |
SNPs
| CDK5RAP1 |
Gene Sequence
|
>3606 bp
ATGCACCCTTTACAGTGTGTCCTCCAAGTGCAGAGGTCTCTGGGGTGGGGACCATTGGCC
TCTGTGTCTTGGCTGTCGCTGAGGATGTGCAGGGCACACAGCAGTCTCTCTAGTACCATG
TGTCCCAGTCCAGAGAGGCAGGAGGATGGAGCTCGGAAGGATTTCAGCTCCAGGCTGGCT
GCTGGACCGACTTTTCAACATTTTTTAAAAAGTGCCTCAGCTCCTCAGGAGAAGCTGTCT
TCAGAAGTGGAAGACCCACCTCCCTATCTCATGATGGATGAACTTCTTGGAAGGCAGAGA
AAAGTCTACCTCGAGACCTATGGCTGCCAGATGAATGTGAATGACACAGAGATAGCCTGG
TCCATCTTACAGAAGAGTGGCTACCTGCGGACCAGTAACCTCCAAGAGGCAGATGTGATT
CTCCTTGTCACATGCTCTATCAGGGAGAAGGCTGAGCAGACCATCTGGAACCGTTTACAT
CAGCTTAAAGCCTTGAAGACAAGGCGGCCCCGCTCCCGGGTTCCTCTGAGGATTGGAATT
CTAGGCTGCATGGCTGAGAGGTTGAAGGAGGAGATTCTCAACAGAGAGAAAATGGTAGAT
ATTTTGGCTGGTCCTGATGCCTACCGGGACCTTCCCCGGCTGCTGGCTGTTGCTGAGTCG
GGCCAGCAAGCTGCCAACGTGCTGCTCTCTCTGGACGAGACCTATGCTGATGTCATGCCA
GTCCAGACAAGCGCCAGTGCCACGTCTGCCTTTGTGTCAATCATGCGAGGCTGTGACAAC
ATGTGTAGCTACTGCATTGTTCCTTTCACCCGGGGCAGGGAGAGGAGTCGGCCTATTGCC
TCCATTCTAGAGGAAGTGAAGAAGCTTTCTGAGCAGGTGTTCCTCCCACCTCGGCCTCCC
AAAGTGTTGGGATTACAGGGGCTGAAAGAAGTGACACTTCTTGGTCAGAATGTTAATAGT
TTTCGGGACAATTCGGAGGTCCAGTTCAACAGTGCAGTGCCTACCAATCTCAGTCGTGGC
TTTACCACCAACTATAAAACCAAGCAAGGAGGACTTCGTTTTGCTCATCTTCTGGATCAG
GTCTCCAGAGTAGATCCTGAAATGAGGATCCGTTTTACCTCTCCCCACCCCAAGGATTTT
CCTGATGAGGTTCTGCAGCTGATTCATGAGAGAGATAACATCTGTAAACAGATCCACCTG
CCAGCCCAGAGTGGAAGCAGCCGTGTGTTGGAGGCCATGCGGAGGGGATATTCAAGAGAA
GCTTATGTGGAGTTAGTTCACCATATTAGAGAATCTATTCCAGGTGTGAGCCTCAGCAGC
GATTTCATTGCTGGCTTTTGTGGTGAGACGGAGGAAGATCACGTCCAGACAGTCTCTTTG
CTCCGGGAAGTTCAGTACAACATGGGCTTCCTCTTTGCCTACAGCATGAGACAGAAGACA
CGGGCATATCATAGGCTGAAGGATGATGTCCCGGAAGAGGTAAAATTAAGGCGTTTGGAG
GAACTCATCACTATCTTCCGAGAAGAAGCAACAAAAGCCAATCAGACCTCTGTGGGCTGT
ACCCAGTTGGTGCTAGTGGAAGGGCTCAGTAAACGCTCTGCCACTGACCTGTGTGGCAGG
AATGATGGAAACCTTAAGGTGATCTTCCCTGATGCAGAGATGGAGGATGTCAATAACCCT
GGGCTCAGGGTCAGAGCCCAGCCTGGGGACTATGTGCTGGTGAAGATCACCTCAGCCAGT
TCTCAGACACTTAGGGGACATGTTCTCTGCAGGACCACTCTGAGGGACTCTTCTGCATAT
TGCTGA
|
Protein Properties |
Number of Residues
| 601 |
Molecular Weight
| 67687.9 |
Theoretical pI
| 8.28 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>CDK5 regulatory subunit-associated protein 1
MHPLQCVLQVQRSLGWGPLASVSWLSLRMCRAHSSLSSTMCPSPERQEDGARKDFSSRLA
AGPTFQHFLKSASAPQEKLSSEVEDPPPYLMMDELLGRQRKVYLETYGCQMNVNDTEIAW
SILQKSGYLRTSNLQEADVILLVTCSIREKAEQTIWNRLHQLKALKTRRPRSRVPLRIGI
LGCMAERLKEEILNREKMVDILAGPDAYRDLPRLLAVAESGQQAANVLLSLDETYADVMP
VQTSASATSAFVSIMRGCDNMCSYCIVPFTRGRERSRPIASILEEVKKLSEQVFLPPRPP
KVLGLQGLKEVTLLGQNVNSFRDNSEVQFNSAVPTNLSRGFTTNYKTKQGGLRFAHLLDQ
VSRVDPEMRIRFTSPHPKDFPDEVLQLIHERDNICKQIHLPAQSGSSRVLEAMRRGYSRE
AYVELVHHIRESIPGVSLSSDFIAGFCGETEEDHVQTVSLLREVQYNMGFLFAYSMRQKT
RAYHRLKDDVPEEVKLRRLEELITIFREEATKANQTSVGCTQLVLVEGLSKRSATDLCGR
NDGNLKVIFPDAEMEDVNNPGLRVRAQPGDYVLVKITSASSQTLRGHVLCRTTLRDSSAY
C
|
External Links |
GenBank ID Protein
| 56205140 |
UniProtKB/Swiss-Prot ID
| Q96SZ6 |
UniProtKB/Swiss-Prot Entry Name
| CK5P1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AL355392 |
GeneCard ID
| CDK5RAP1 |
GenAtlas ID
| CDK5RAP1 |
HGNC ID
| HGNC:15880 |
References |
General References
| Not Available |