Identification |
HMDB Protein ID
| CDBP04176 |
Secondary Accession Numbers
| Not Available |
Name
| Pyridoxal-dependent decarboxylase domain-containing protein 1 |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| PDXDC1 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in carboxy-lyase activity |
Specific Function
| Not Available |
GO Classification
|
Function |
binding |
catalytic activity |
lyase activity |
carbon-carbon lyase activity |
carboxy-lyase activity |
cofactor binding |
pyridoxal phosphate binding |
Process |
carboxylic acid metabolic process |
metabolic process |
cellular metabolic process |
organic acid metabolic process |
oxoacid metabolic process |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:1 |
Locus
| 16p13.11 |
SNPs
| PDXDC1 |
Gene Sequence
|
>2367 bp
ATGGACGCGTCCCTGGAGAAGATAGCAGACCCCACGTTAGCTGAAATGGGAAAAAACTTG
AAGGAGGCAGTGAAGATGCTGGAGGACAGTCAGAGAAGAACAGAAGAGGAAAATGGAAAG
AAGCTCATATCCGGAGATATTCCAGGCCCACTCCAGGGCAGTGGGCAAGATATGGTGAGC
ATCCTCCAGTTAGTTCAGAATCTCATGCATGGAGATGAAGATGAGGAGCCCCAGAGCCCC
AGAATCCAAAATATTGGAGAACAAGGTCATATGGCTTTGTTGGGACATAGTCTGGGAGCT
TATATTTCAACTCTGGACAAAGAGAAGCTGAGAAAACTTACAACTAGGATACTTTCAGAT
ACCACCTTATGGCTATGCAGAATTTTCAGATATGAAAATGGGTGTGCTTATTTCCACGAA
GAGGAAAGAGAAGGACTTGCAAAGATATGTAGGCTTGCCATTCATTCTCGATATGAAGAC
TTCGTAGTGGATGGCTTCAATGTGTTATATAACAAGAAGCCTGTCATATATCTTAGTGCT
GCTGCTAGACCTGGCCTGGGCCAATACCTTTGTAATCAGCTCGGCTTGCCCTTCCCCTGC
TTGTGCCGTGTACCCTGTAACACTGTGTTTGGATCCCAGCATCAGATGGATGTTGCCTTC
CTGGAGAAACTGATTAAAGATGATATAGAGCGAGGAAGACTGCCCCTGTTGCTTGTCGCA
AATGCAGGAACGGCAGCAGTAGGACACACAGACAAGATTGGGAGATTGAAAGAACTCTGT
GAGCAGTATGGCATATGGCTTCATGTGGAGGGTGTGAATCTGGCAACATTGGCTCTGGGT
TATGTCTCCTCATCAGTGCTGGCTGCAGCCAAATGTGATAGCATGACGATGACTCCTGGC
CCGTGGCTGGGTTTGCCAGCTGTTCCTGCGGTGACACTGTATAAACACGATGACCCTGCC
TTGACTTTAGTTGCTGGTCTTACATCAAATAAGCCCACAGACAAACTCCGTGCCCTGCCT
CTGTGGTTATCTTTACAATACTTGGGACTTGATGGGTTTGTGGAGAGGATCAAGCATGCC
TGTCAACTGAGTCAACGGTTGCAGGAAAGTTTGAAGAAAGTGAATTACATCAAAATCTTG
GTGGAAGATGAGCTCAGCTCCCCAGTGGTGGTGTTCAGATTTTTCCAGGAATTACCAGGC
TCAGATCCGGTGTTTAAAGCCGTCCCAGTGCCCAACATGACACCTTCAGGAGTCGGCCGG
GAGAGGCACTCGTGTGACGCGCTGAATCGCTGGCTGGGAGAACAGCTGAAGCAGCTGGTG
CCTGCAAGCGGCCTCACAGTCATGGATCTGGAAGCTGAGGGCACGTGTTTGCGGTTCAGC
CCTTTGATGACCGCAGCAGTTTTAGGAACTCGGGGAGAGGATGTGGATCAGCTCGTAGCC
TGCATAGAAAGCAAACTGCCAGTGCTGTGCTGTACGCTCCAGTTGCGTGAAGAGTTCAAG
CAGGAAGTGGAAGCAACAGCAGGTCTCCTATATGTTGATGACCCTAACTGGTCTGGAATA
GGGGTTGTCAGGTATGAACATGCTAATGATGATAAGAGCAGTTTGAAATCAGATCCCGAA
GGGGAAAACATCCATGCTGGACTCCTGAAGAAGTTAAATGAACTGGAATCTGACCTAACC
TTTAAAATAGGCCCTGAGTATAAGAGCATGAAGAGCTGCCTTTATGTCGGCATGGCGAGC
GACAACGTCGATGCTGCTGAGCTCGTGGAGACCATTGCGGCCACAGCCCGGGAGATAGAG
GAGAACTCGAGGCTTCTGGAAAACATGACAGAAGTGGTTCGGAAAGGCATTCAGGAAGCT
CAAGTGGAGCTGCAGAAGGCAAGTGAAGAACGGCTTCTGGAAGAGGGGGTGTTGCGGCAG
ATCCCTGTAGTGGGCTCCGTGCTGAATTGGTTTTCTCCGGTCCAGGCTTTACAGAAGGGA
AGAACTTTTAACTTGACAGCAGGCTCTCTGGAGTCCACAGAACCCATATATGTCTACAAA
GCACAAGGTGCAGGAGTCACGCTGCCTCCAACGCCCTCGGGCAGTCGCACCAAGCAGAGG
CTTCCAGGCCAGAAGCCTTTTAAAAGGTCCCTGCGAGGTTCAGATGCTTTGAGTGAGACC
AGCTCAGTCAGTCACATTGAAGACTTAGAAAAGGTGGAGCGCCTATCCAGTGGGCCGGAG
CAGATCACCCTCGAGGCCAGCAGCACTGAGGGACACCCAGGGGCTCCCAGCCCTCAGCAC
ACCGACCAGACCGAGGCCTTCCAGAAAGGGGTCCCACACCCAGAAGATGACCACTCACAG
GTAGAAGGACCGGAGAGCTTAAGATGA
|
Protein Properties |
Number of Residues
| 788 |
Molecular Weight
| 86706.1 |
Theoretical pI
| 5.05 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Pyridoxal-dependent decarboxylase domain-containing protein 1
MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
VEGPESLR
|
External Links |
GenBank ID Protein
| 190341074 |
UniProtKB/Swiss-Prot ID
| Q6P996 |
UniProtKB/Swiss-Prot Entry Name
| PDXD1_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| NM_015027.2 |
GeneCard ID
| PDXDC1 |
GenAtlas ID
| PDXDC1 |
HGNC ID
| HGNC:28995 |
References |
General References
| Not Available |