Identification
HMDB Protein ID CDBP04176
Secondary Accession Numbers Not Available
Name Pyridoxal-dependent decarboxylase domain-containing protein 1
Description Not Available
Synonyms Not Available
Gene Name PDXDC1
Protein Type Enzyme
Biological Properties
General Function Involved in carboxy-lyase activity
Specific Function Not Available
GO Classification
Function
binding
catalytic activity
lyase activity
carbon-carbon lyase activity
carboxy-lyase activity
cofactor binding
pyridoxal phosphate binding
Process
carboxylic acid metabolic process
metabolic process
cellular metabolic process
organic acid metabolic process
oxoacid metabolic process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 16p13.11
SNPs PDXDC1
Gene Sequence
>2367 bp
ATGGACGCGTCCCTGGAGAAGATAGCAGACCCCACGTTAGCTGAAATGGGAAAAAACTTG
AAGGAGGCAGTGAAGATGCTGGAGGACAGTCAGAGAAGAACAGAAGAGGAAAATGGAAAG
AAGCTCATATCCGGAGATATTCCAGGCCCACTCCAGGGCAGTGGGCAAGATATGGTGAGC
ATCCTCCAGTTAGTTCAGAATCTCATGCATGGAGATGAAGATGAGGAGCCCCAGAGCCCC
AGAATCCAAAATATTGGAGAACAAGGTCATATGGCTTTGTTGGGACATAGTCTGGGAGCT
TATATTTCAACTCTGGACAAAGAGAAGCTGAGAAAACTTACAACTAGGATACTTTCAGAT
ACCACCTTATGGCTATGCAGAATTTTCAGATATGAAAATGGGTGTGCTTATTTCCACGAA
GAGGAAAGAGAAGGACTTGCAAAGATATGTAGGCTTGCCATTCATTCTCGATATGAAGAC
TTCGTAGTGGATGGCTTCAATGTGTTATATAACAAGAAGCCTGTCATATATCTTAGTGCT
GCTGCTAGACCTGGCCTGGGCCAATACCTTTGTAATCAGCTCGGCTTGCCCTTCCCCTGC
TTGTGCCGTGTACCCTGTAACACTGTGTTTGGATCCCAGCATCAGATGGATGTTGCCTTC
CTGGAGAAACTGATTAAAGATGATATAGAGCGAGGAAGACTGCCCCTGTTGCTTGTCGCA
AATGCAGGAACGGCAGCAGTAGGACACACAGACAAGATTGGGAGATTGAAAGAACTCTGT
GAGCAGTATGGCATATGGCTTCATGTGGAGGGTGTGAATCTGGCAACATTGGCTCTGGGT
TATGTCTCCTCATCAGTGCTGGCTGCAGCCAAATGTGATAGCATGACGATGACTCCTGGC
CCGTGGCTGGGTTTGCCAGCTGTTCCTGCGGTGACACTGTATAAACACGATGACCCTGCC
TTGACTTTAGTTGCTGGTCTTACATCAAATAAGCCCACAGACAAACTCCGTGCCCTGCCT
CTGTGGTTATCTTTACAATACTTGGGACTTGATGGGTTTGTGGAGAGGATCAAGCATGCC
TGTCAACTGAGTCAACGGTTGCAGGAAAGTTTGAAGAAAGTGAATTACATCAAAATCTTG
GTGGAAGATGAGCTCAGCTCCCCAGTGGTGGTGTTCAGATTTTTCCAGGAATTACCAGGC
TCAGATCCGGTGTTTAAAGCCGTCCCAGTGCCCAACATGACACCTTCAGGAGTCGGCCGG
GAGAGGCACTCGTGTGACGCGCTGAATCGCTGGCTGGGAGAACAGCTGAAGCAGCTGGTG
CCTGCAAGCGGCCTCACAGTCATGGATCTGGAAGCTGAGGGCACGTGTTTGCGGTTCAGC
CCTTTGATGACCGCAGCAGTTTTAGGAACTCGGGGAGAGGATGTGGATCAGCTCGTAGCC
TGCATAGAAAGCAAACTGCCAGTGCTGTGCTGTACGCTCCAGTTGCGTGAAGAGTTCAAG
CAGGAAGTGGAAGCAACAGCAGGTCTCCTATATGTTGATGACCCTAACTGGTCTGGAATA
GGGGTTGTCAGGTATGAACATGCTAATGATGATAAGAGCAGTTTGAAATCAGATCCCGAA
GGGGAAAACATCCATGCTGGACTCCTGAAGAAGTTAAATGAACTGGAATCTGACCTAACC
TTTAAAATAGGCCCTGAGTATAAGAGCATGAAGAGCTGCCTTTATGTCGGCATGGCGAGC
GACAACGTCGATGCTGCTGAGCTCGTGGAGACCATTGCGGCCACAGCCCGGGAGATAGAG
GAGAACTCGAGGCTTCTGGAAAACATGACAGAAGTGGTTCGGAAAGGCATTCAGGAAGCT
CAAGTGGAGCTGCAGAAGGCAAGTGAAGAACGGCTTCTGGAAGAGGGGGTGTTGCGGCAG
ATCCCTGTAGTGGGCTCCGTGCTGAATTGGTTTTCTCCGGTCCAGGCTTTACAGAAGGGA
AGAACTTTTAACTTGACAGCAGGCTCTCTGGAGTCCACAGAACCCATATATGTCTACAAA
GCACAAGGTGCAGGAGTCACGCTGCCTCCAACGCCCTCGGGCAGTCGCACCAAGCAGAGG
CTTCCAGGCCAGAAGCCTTTTAAAAGGTCCCTGCGAGGTTCAGATGCTTTGAGTGAGACC
AGCTCAGTCAGTCACATTGAAGACTTAGAAAAGGTGGAGCGCCTATCCAGTGGGCCGGAG
CAGATCACCCTCGAGGCCAGCAGCACTGAGGGACACCCAGGGGCTCCCAGCCCTCAGCAC
ACCGACCAGACCGAGGCCTTCCAGAAAGGGGTCCCACACCCAGAAGATGACCACTCACAG
GTAGAAGGACCGGAGAGCTTAAGATGA
Protein Properties
Number of Residues 788
Molecular Weight 86706.1
Theoretical pI 5.05
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>Pyridoxal-dependent decarboxylase domain-containing protein 1
MDASLEKIADPTLAEMGKNLKEAVKMLEDSQRRTEEENGKKLISGDIPGPLQGSGQDMVS
ILQLVQNLMHGDEDEEPQSPRIQNIGEQGHMALLGHSLGAYISTLDKEKLRKLTTRILSD
TTLWLCRIFRYENGCAYFHEEEREGLAKICRLAIHSRYEDFVVDGFNVLYNKKPVIYLSA
AARPGLGQYLCNQLGLPFPCLCRVPCNTVFGSQHQMDVAFLEKLIKDDIERGRLPLLLVA
NAGTAAVGHTDKIGRLKELCEQYGIWLHVEGVNLATLALGYVSSSVLAAAKCDSMTMTPG
PWLGLPAVPAVTLYKHDDPALTLVAGLTSNKPTDKLRALPLWLSLQYLGLDGFVERIKHA
CQLSQRLQESLKKVNYIKILVEDELSSPVVVFRFFQELPGSDPVFKAVPVPNMTPSGVGR
ERHSCDALNRWLGEQLKQLVPASGLTVMDLEAEGTCLRFSPLMTAAVLGTRGEDVDQLVA
CIESKLPVLCCTLQLREEFKQEVEATAGLLYVDDPNWSGIGVVRYEHANDDKSSLKSDPE
GENIHAGLLKKLNELESDLTFKIGPEYKSMKSCLYVGMASDNVDAAELVETIAATAREIE
ENSRLLENMTEVVRKGIQEAQVELQKASEERLLEEGVLRQIPVVGSVLNWFSPVQALQKG
RTFNLTAGSLESTEPIYVYKAQGAGVTLPPTPSGSRTKQRLPGQKPFKRSLRGSDALSET
SSVSHIEDLEKVERLSSGPEQITLEASSTEGHPGAPSPQHTDQTEAFQKGVPHPEDDHSQ
VEGPESLR
GenBank ID Protein 190341074
UniProtKB/Swiss-Prot ID Q6P996
UniProtKB/Swiss-Prot Entry Name PDXD1_HUMAN
PDB IDs Not Available
GenBank Gene ID NM_015027.2
GeneCard ID PDXDC1
GenAtlas ID PDXDC1
HGNC ID HGNC:28995
References
General References Not Available