Identification |
HMDB Protein ID
| CDBP04170 |
Secondary Accession Numbers
| Not Available |
Name
| Pyruvate kinase |
Description
| Not Available |
Synonyms
|
Not Available
|
Gene Name
| Not Available |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in magnesium ion binding |
Specific Function
| ATP + pyruvate = ADP + phosphoenolpyruvate |
GO Classification
|
Function |
pyruvate kinase activity |
ion binding |
cation binding |
metal ion binding |
binding |
catalytic activity |
transferase activity |
transferase activity, transferring phosphorus-containing groups |
kinase activity |
magnesium ion binding |
alkali metal ion binding |
potassium ion binding |
Process |
metabolic process |
small molecule metabolic process |
alcohol metabolic process |
monosaccharide metabolic process |
hexose metabolic process |
glucose metabolic process |
glucose catabolic process |
glycolysis |
|
Cellular Location
|
Not Available
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Not Available |
Locus
| Not Available |
SNPs
| Not Available |
Gene Sequence
|
>1764 bp
CATTCCATGGTCCCGCAGCCCCAGGCCCACACTGAAAGCATGTCGATCCAGGAGAACATA
TCATCCCTGCAGCTTCGGTCATGGGTCTCTAAGTCCCAAAGAGACTTAGCAAAGTCCATC
CTGATTGGGGCTCCAGGAGGGCCAGCGGGGTATCTGCGGCGGGCCAGTGTGGCCCAACTG
ACCCAGGAGCTGGGCACTGCCTTCTTCCAGCAGCAGCAGCTGCCAGCTGCTATGGCAGAC
ACCTTCCTGGAACACCTCTGCCTACTGGACATTGACTCCGAGCCCGTGGCTGCTCGCAGT
ACCAGCATCATTGCCACCATCGGGCCAGCATCTCGCTCCGTGGAGCGCCTCAAGGAGATG
ATCAAGGCCGGGATGAACATTGCGCGACTCAACTTCTCCCACGGCTCCCACGAGTACCAT
GCTGAGTCCATCGCCAACGTCCGGGAGGCGGTGGAGAGCTTTGCAGGTTCCCCACTCAGC
TACCGGCCCGTGGCCATCGCCCTGGACACCAAGGGACCGGAGATCCGCACTGGGATCCTG
CAGGGGGGTCCAGAGTCGGAAGTGGAGCTGGTGAAGGGCTCCCAGGTGCTGGTGACTGTG
GACCCCGCGTTCCGGACGCGGGGGAACGCGAACACCGTGTGGGTGGACTACCCCAATATT
GTCCGGGTCGTGCCGGTGGGGGGCCGCATCTACATTGACGACGGGCTCATCTCCCTAGTG
GTCCAGAAAATCGGCCCAGAGGGACTGGTGACCCAAGTGGAGAACGGCGGCGTCCTGGGC
AGCCGGAAGGGCGTGAACTTGCCAGGGGCCCAGGTGGACTTGCCCGGGCTGTCCGAGCAG
GACGTCCGAGACCTGCGCTTCGGGGTGGAGCATGGGGTGGACATCGTCTTTGCCTCCTTT
GTGCGGAAAGCCAGCGACGTGGCTGCCGTCAGGGCTGCTCTGGGTCCGGAAGGACACGGC
ATCAAGATCATCAGCAAAATTGAGAACCACGAAGGCGTGAAGAGGTTTGATGAAATCCTG
GAGGTGAGCGACGGCATCATGGTGGCACGGGGGGACCTAGGCATCGAGATCCCAGCAGAG
AAGGTTTTCCTGGCTCAGAAGATGATGATTGGGCGCTGCAACTTGGCGGGCAAGCCTGTT
GTCTGTGCCACACAGATGCTGGAGAGCATGATTACCAAGCCCCGGCCAACGAGGGCAGAG
ACAAGCGATGTCGCCAATGCTGTGCTGGATGGGGCTGACTGCATCATGCTGTCAGGGGAG
ACTGCCAAGGGCAACTTCCCTGTGGAAGCGGTGAAGATGCAGCATGCGATTGCCCGGGAG
GCAGAGGCCGCAGTGTACCACCGGCAGCTGTTTGAGGAGCTACGTCGGGCAGCGCCACTA
AGCCGTGATCCCACTGAGGTCACCGCCATTGGTGCTGTGGAGGCTGCCTTCAAGTGCTGT
GCTGCTGCCATCATTGTGCTGACCACAACTGGCCGCTCAGCCCAGCTTCTGTCTCGGTAC
CGACCTCGGGCAGCAGTCATTGCTGTCACCCGCTCTGCCCAGGCTGCCCGCCAGGTCCAC
TTATGCCGAGGAGTCTTCCCCTTGCTTTACCGTGAACCTCCAGAAGCCATCTGGGCAGAT
GATGTAGATCGCCGGGTGCAATTTGGCATTGAAAGTGGAAAGCTCCGTGGCTTCCTCCGT
GTTGGAGACCTGGTGATTGTGGTGACAGGCTGGCGACCTGGCTCCGGCTACACCAACATC
ATGCGGGTGCTAAGCATATCCTGA
|
Protein Properties |
Number of Residues
| 587 |
Molecular Weight
| 63260.1 |
Theoretical pI
| 7.6 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>Pyruvate kinase
HSMVPQPQAHTESMSIQENISSLQLRSWVSKSQRDLAKSILIGAPGGPAGYLRRASVAQL
TQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEM
IKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGIL
QGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLV
VQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASF
VRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAE
KVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGE
TAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCC
AAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWAD
DVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSIS
|
External Links |
GenBank ID Protein
| 1230589 |
UniProtKB/Swiss-Prot ID
| Q16715 |
UniProtKB/Swiss-Prot Entry Name
| Q16715_HUMAN |
PDB IDs
|
|
GenBank Gene ID
| U47654 |
GeneCard ID
| Not Available |
GenAtlas ID
| Not Available |
HGNC ID
| HGNC:9020 |
References |
General References
| Not Available |