Cannabis Compound Database: Showing Protein Myotubularin-related protein 14 (CDBP04132)

Identification Biological properties Gene properties Protein properties External links References XML Show 0 compounds

Identification

HMDB Protein ID

CDBP04132

Secondary Accession Numbers

Not Available

Name

Myotubularin-related protein 14

Description

Not Available

Synonyms

HCV NS5A-transactivated protein 4 splice variant A-binding protein 1
NS5ATP4ABP1
hJumpy

Gene Name

MTMR14

Protein Type

Enzyme

Biological Properties

General Function

Involved in protein tyrosine phosphatase activity

Specific Function

Lipid phosphatase which efficiently dephosphorylates phosphatidylinositol 3-phosphate (PtdIns3P) and PtdIns(3,5)P2; inactive toward PtdIns4P, PtdIns(3,4)P2, PtdIns(4,5)P2 and PtdIns(3,4,5)P3

GO Classification

Function
phosphoprotein phosphatase activity
protein tyrosine phosphatase activity
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
phosphatase activity
Process
metabolic process
cellular metabolic process
phosphorus metabolic process
phosphate metabolic process
dephosphorylation

Cellular Location

Cytoplasm

Pathways

Not Available

Gene Properties

Chromosome Location

Chromosome:3

Locus

3p26

SNPs

MTMR14

Gene Sequence

>1953 bp
ATGGCCGGCGCTCGGGCCGCCGCCGCCGCTGCCTCGGCGGGGTCCTCGGCCTCTTCAGGC
AACCAGCCGCCTCAGGAGCTGGGGCTTGGGGAGCTGCTGGAGGAGTTCTCCCGGACTCAG
TACCGGGCCAAGGATGGCAGCGGGACCGGCGGCTCTAAGGTTGAGCGCATTGAGAAGAGA
TGTCTGGAGCTGTTTGGCCGAGACTACTGTTTCAGCGTGATTCCAAACACGAATGGGGAT
ATCTGTGGCCACTATCCCCGGCACATCGTGTTCCTGGAGTATGAGAGTTCTGAGAAGGAG
AAAGACACGTTTGAGAGTACCGTACAGGTGAGCAAGTTGCAAGACCTCATCCACCGCAGC
AAGATGGCCCGGTGCAGAGGACGGTTTGTCTGCCCAGTAATCCTGTTCAAGGGCAAGCAC
ATTTGCAGGTCGGCCACACTGGCTGGATGGGGAGAGCTGTATGGACGCTCAGGCTACAAC
TATTTTTTCTCAGGGGGTGCAGATGATGCCTGGGCAGATGTGGAGGACGTCACGGAGGAG
GACTGTGCTCTTCGAAGTGGTGACACGCATCTTTTTGATAAGGTCAGAGGCTATGACATC
AAGCTGCTTCGATACCTGTCAGTCAAATACATCTGTGACCTGATGGTGGAGAACAAGAAG
GTGAAGTTTGGCATGAATGTAACCTCCTCTGAGAAGGTGGACAAAGCCCAGCGCTATGCC
GACTTCACTCTCCTCTCCATCCCGTATCCAGGCTGTGAATTTTTCAAGGAATATAAAGAT
CGGGATTACATGGCAGAAGGGCTCATATTTAACTGGAAGCAGGACTACGTTGATGCCCCA
TTGAGCATCCCCGACTTCCTGACTCACTCTCTGAACATTGACTGGAGCCAGTATCAGTGT
TGGGATCTGGTGCAACAAACACAAAACTACCTGAAGCTGCTGCTTTCCTTAGTTAACAGT
GATGATGACAGCGGGCTGCTGGTACACTGTATCTCAGGCTGGGATCGGACCCCCCTCTTC
ATCTCCCTCCTGCGCCTTTCCTTGTGGGCTGATGGGCTCATCCACACGTCCCTGAAGCCC
ACTGAGATCCTCTACCTCACTGTGGCCTATGACTGGTTCCTCTTCGGGCACATGTTGGTA
GATCGGCTCAGCAAAGGGGAGGAGATTTTCTTCTTCTGCTTCAATTTTTTGAAGCATATT
ACCTCCGAGGAGTTCTCTGCTCTGAAGACCCAGAGGAGGAAGAGTTTGCCAGCCCGGGAT
GGAGGCTTCACCCTGGAAGACATCTGCATGCTGAGACGAAAGGACCGTGGCAGCACCACC
AGCCTTGGCAGCGACTTCTCCCTGGTCATGGAGAGTTCCCCAGGAGCCACTGGGAGCTTC
ACCTATGAGGCCGTGGAGCTGGTCCCAGCAGGAGCGCCAACTCAGGCAGCTTGGAGGAAG
AGCCACTCATCCTCTCCACAGAGTGTCCTCTGGAACCGGCCACAACCCTCAGAGGACCGC
TTGCCTTCCCAGCAGGGGCTGGCGGAAGCCAGGTCTTCCAGCTCCTCTTCCTCAAACCAT
TCTGATAACTTTTTCAGGATGGGTAGCAGTCCCCTGGAGGTCCCCAAACCCAGATCAGTG
GACCATCCCCTGCCCGGATCCTCTCTCTCCACAGACTATGGCAGCTGGCAGATGGTAACG
GGCTGTGGCAGTATTCAGGAGCGGGCTGTCCTGCACACAGACTCCTCTCTCCCTTTCAGC
TTCCCGGATGAGCTCCCTAACAGTTGTCTGCTTGCAGCCCTGAGTGATCGAGAGACTCGG
CTGCAGGAGGTGCGCTCAGCCTTCTTGGCTGCGTACAGCAGCACAGTGGGGCTTCGGGCA
GTAGCCCCCAGTCCTTCCGGTGCCATCGGGGGCCTGCTGGAGCAATTTGCCCGTGGTGTT
GGACTCCGGAGCATCAGCAGCAATGCCTTGTGA

Protein Properties

Number of Residues

650

Molecular Weight

72202.6

Theoretical pI

6.17

Pfam Domain Function

Not Available

Signals

["None"]

Transmembrane Regions

["None"]

Protein Sequence

>Myotubularin-related protein 14
MAGARAAAAAASAGSSASSGNQPPQELGLGELLEEFSRTQYRAKDGSGTGGSKVERIEKR
CLELFGRDYCFSVIPNTNGDICGHYPRHIVFLEYESSEKEKDTFESTVQVSKLQDLIHRS
KMARCRGRFVCPVILFKGKHICRSATLAGWGELYGRSGYNYFFSGGADDAWADVEDVTEE
DCALRSGDTHLFDKVRGYDIKLLRYLSVKYICDLMVENKKVKFGMNVTSSEKVDKAQRYA
DFTLLSIPYPGCEFFKEYKDRDYMAEGLIFNWKQDYVDAPLSIPDFLTHSLNIDWSQYQC
WDLVQQTQNYLKLLLSLVNSDDDSGLLVHCISGWDRTPLFISLLRLSLWADGLIHTSLKP
TEILYLTVAYDWFLFGHMLVDRLSKGEEIFFFCFNFLKHITSEEFSALKTQRRKSLPARD
GGFTLEDICMLRRKDRGSTTSLGSDFSLVMESSPGATGSFTYEAVELVPAGAPTQAAWRK
SHSSSPQSVLWNRPQPSEDRLPSQQGLAEARSSSSSSSNHSDNFFRMGSSPLEVPKPRSV
DHPLPGSSLSTDYGSWQMVTGCGSIQERAVLHTDSSLPFSFPDELPNSCLLAALSDRETR
LQEVRSAFLAAYSSTVGLRAVAPSPSGAIGGLLEQFARGVGLRSISSNAL

External Links

GenBank ID Protein

117938270

UniProtKB/Swiss-Prot ID

Q8NCE2

UniProtKB/Swiss-Prot Entry Name

MTMRE_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_001077525.2

GeneCard ID