| Identification |
|---|
| HMDB Protein ID
| CDBP04114 |
| Secondary Accession Numbers
| Not Available |
| Name
| Dual specificity protein phosphatase 13 |
| Description
| Not Available |
| Synonyms
|
- Dual specificity phosphatase SKRP4
- Testis- and skeletal-muscle-specific DSP
|
| Gene Name
| DUSP13 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphatase activity |
| Specific Function
| May be involved in the regulation of meiosis and/or differentiation of testicular germ cells during spermatogenesis. Exhibits intrinsic phosphatase activity towards both phospho-seryl/threonyl and -tyrosyl residues of myelin basic protein, with similar specific activities in vitro.
|
| GO Classification
|
| Biological Process |
| spermatogenesis |
| meiosis |
| peptidyl-tyrosine dephosphorylation |
| Function |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| phosphoric ester hydrolase activity |
| phosphatase activity |
| protein tyrosine/serine/threonine phosphatase activity |
| phosphoprotein phosphatase activity |
| protein tyrosine phosphatase activity |
| Molecular Function |
| protein tyrosine/serine/threonine phosphatase activity |
| protein tyrosine phosphatase activity |
| Process |
| phosphorus metabolic process |
| phosphate metabolic process |
| dephosphorylation |
| protein amino acid dephosphorylation |
| metabolic process |
| cellular metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 10q22.2 |
| SNPs
| DUSP13 |
| Gene Sequence
|
>597 bp
ATGGACTCACTGCAGAAGCAGGACCTCCGGAGGCCCAAGATCCATGGGGCAGTCCAGGCA
TCTCCCTACCAGCCGCCCACATTGGCTTCGCTGCAGCGCTTGCTGTGGGTCCGTCAGGCT
GCCACACTGAACCATATCGATGAGGTCTGGCCCAGCCTCTTCCTGGGAGATGCGTACGCA
GCCCGGGACAAGAGCAAGCTGATCCAGCTGGGAATCACCCACGTTGTGAATGCCGCTGCA
GGCAAGTTCCAGGTGGACACAGGTGCCAAATTCTACCGTGGAATGTCCCTGGAGTACTAT
GGCATCGAGGCGGACGACAACCCCTTCTTCGACCTCAGTGTCTACTTTCTGCCTGTTGCT
CGATACATCCGAGCTGCCCTCAGTGTTCCCCAAGGCCGCGTGCTGGTACACTGTGCCATG
GGGGTAAGCCGCTCTGCCACACTTGTCCTGGCCTTCCTCATGATCTGTGAGAACATGACG
CTGGTAGAGGCCATCCAGACGGTGCAGGCCCACCGCAATATCTGCCCTAACTCAGGCTTC
CTCCGGCAGCTCCAGGTTCTGGACAACCGACTGGGGCGGGAGACGGGGCGGTTCTGA
|
| Protein Properties |
|---|
| Number of Residues
| 198 |
| Molecular Weight
| 20657.415 |
| Theoretical pI
| 7.505 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Dual specificity protein phosphatase 13
MDSLQKQDLRRPKIHGAVQASPYQPPTLASLQRLLWVRQAATLNHIDEVWPSLFLGDAYA
ARDKSKLIQLGITHVVNAAAGKFQVDTGAKFYRGMSLEYYGIEADDNPFFDLSVYFLPVA
RYIRAALSVPQGRVLVHCAMGVSRSATLVLAFLMICENMTLVEAIQTVQAHRNICPNSGF
LRQLQVLDNRLGRETGRF
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9UII6 |
| UniProtKB/Swiss-Prot Entry Name
| DUS13_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AB027004 |
| GeneCard ID
| DUSP13 |
| GenAtlas ID
| DUSP13 |
| HGNC ID
| HGNC:19681 |
| References |
|---|
| General References
| Not Available |