| Identification |
|---|
| HMDB Protein ID
| CDBP04099 |
| Secondary Accession Numbers
| Not Available |
| Name
| MOSC domain-containing protein 2, mitochondrial |
| Description
| Not Available |
| Synonyms
|
Not Available
|
| Gene Name
| MOSC2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Catalytic component of the benzamidoxime prodrug- converting complex, a complex required to reduce N-hydroxylated structures, such as benzamidoxime prodrug. Benzamidoxime is an amidine prodrug produced by N-hydroxylation which is used to enhance bioavailability and increase intestinal absorption. It is then reduced into benzamidine, its active amidine, by the benzamidoxime prodrug-converting complex |
| GO Classification
|
| Function |
| transition metal ion binding |
| cofactor binding |
| pyridoxal phosphate binding |
| molybdenum ion binding |
| ion binding |
| cation binding |
| metal ion binding |
| binding |
| catalytic activity |
|
| Cellular Location
|
- Peripheral membrane protein
- Mitochondrion outer membrane
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:1 |
| Locus
| 1q41 |
| SNPs
| MOSC2 |
| Gene Sequence
|
>1008 bp
ATGGGCGCTTCCAGCTCCTCCGCGCTGGCCCGCCTCGGCCTCCCAGCCCGGCCCTGGCCC
AGGTGGCTCGGGGTCGCCGCGCTAGGACTGGCCGCCGTGGCCCTGGGGACTGTCGCCTGG
CGCCGCGCATGGCCCAGGCGGCGCCGGCGGCTGCAGCAGGTGGGCACCGTGGCGAAGCTC
TGGATCTACCCGGTGAAATCCTGCAAAGGGGTGCCGGTGAGCGAGGCTGAGTGCACGGCC
ATGGGGCTGCGCAGCGGCAACCTGCGGGACAGGTTTTGGCTGGTGATTAAGGAAGATGGA
CACATGGTCACTGCCCGACAGGAGCCTCGCCTCGTGCTCATCTCCATCATTTATGAGAAT
AACTGCCTGATCTTCAGGGCTCCAGACATGGACCAGCTGGTTTTGCCTAGCAAGCAGCCT
TCCTCAAACAAACTCCACAACTGCAGGATATTTGGCCTTGACATTAAAGGCAGAGACTGT
GGCAATGAGGCAGCTAAGTGGTTCACCAACTTCTTGAAAACTGAAGCGTATAGATTGGTT
CAATTTGAGACAAACATGAAGGGAAGAACATCAAGAAAACTTCTCCCCACTCTTGATCAG
AATTTCCAGGTGGCCTACCCAGACTACTGCCCGCTCCTGATCATGACAGATGCCTCCCTG
GTAGATTTGAATACCAGGATGGAGAAGAAAATGAAAATGGAGAATTTCAGGCCAAATATT
GTGGTGACCGGCTGTGATGCTTTTGAGGAGGATACCTGGGATGAACTCCTAATTGGTAGT
GTAGAAGTGAAAAAGGTAATGGCATGCCCCAGGTGTATTTTGACAACGGTGGACCCAGAC
ACTGGAGTCATAGACAGGAAACAGCCACTGGACACCCTGAAGAGCTACCGCCTGTGTGAT
CCTTCTGAGAGGGAATTGTACAAGTTGTCTCCACTTTTTGGGATCTATTATTCAGTGGAA
AAAATTGGAAGCCTGAGAGTTGGTGACCCTGTGTATCGGATGGTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 335 |
| Molecular Weight
| 38023.0 |
| Theoretical pI
| 9.5 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>MOSC domain-containing protein 2, mitochondrial
MGASSSSALARLGLPARPWPRWLGVAALGLAAVALGTVAWRRAWPRRRRRLQQVGTVAKL
WIYPVKSCKGVPVSEAECTAMGLRSGNLRDRFWLVIKEDGHMVTARQEPRLVLISIIYEN
NCLIFRAPDMDQLVLPSKQPSSNKLHNCRIFGLDIKGRDCGNEAAKWFTNFLKTEAYRLV
QFETNMKGRTSRKLLPTLDQNFQVAYPDYCPLLIMTDASLVDLNTRMEKKMKMENFRPNI
VVTGCDAFEEDTWDELLIGSVEVKKVMACPRCILTTVDPDTGVIDRKQPLDTLKSYRLCD
PSERELYKLSPLFGIYYSVEKIGSLRVGDPVYRMV
|
| External Links |
|---|
| GenBank ID Protein
| 31542713 |
| UniProtKB/Swiss-Prot ID
| Q969Z3 |
| UniProtKB/Swiss-Prot Entry Name
| MOSC2_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| NM_017898.3 |
| GeneCard ID
| MOSC2 |
| GenAtlas ID
| MOSC2 |
| HGNC ID
| HGNC:26064 |
| References |
|---|
| General References
| Not Available |