Identification
HMDB Protein ID CDBP04097
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
Description Not Available
Synonyms
  1. Hormone-regulated proliferation-associated protein of 20 kDa
Gene Name NDUFAF4
Protein Type Enzyme
Biological Properties
General Function Involved in calmodulin binding
Specific Function Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion
GO Classification Not Available
Cellular Location
  1. Mitochondrion
Pathways
Gene Properties
Chromosome Location Chromosome:6
Locus 6q16.1
SNPs NDUFAF4
Gene Sequence
>528 bp
ATGGGAGCACTAGTGATTCGCGGTATCAGGAATTTCAACCTAGAGAACCGAGCGGAACGG
GAAATCAGCAAGATGAAGCCCTCTGTCGCTCCCAGACACCCCTCTACCAACAGCCTCCTG
CGAGAGCAGATTAGTCTCTATCCAGAAGTTAAAGGAGAGATTGCTCGTAAAGATGAAAAG
CTGCTGTCGTTTCTAAAAGATGTGTATGTTGATTCCAAAGATCCTGTGTCTTCCTTGCAG
GTAAAAGCTGCTGAAACATGTCAAGAGCCGAAGGAATTCAGATTGCCGAAAGACCATCAT
TTTGATATGATAAATATTAAGAGCATTCCCAAAGGCAAAATTTCCATTGTAGAAGCATTG
ACACTTCTCAATAATCATAAGCTTTTCCCAGAAACCTGGACTGCTGAGAAAATAATGCAA
GAATACCAGTTAGAACAGAAAGATGTGAATTCTCTTCTTAAATATTTTGTTACTTTTGAA
GTCGAAATCTTCCCTCCTGAAGACAAGAAAGCAATACGATCAAAATGA
Protein Properties
Number of Residues 175
Molecular Weight 20266.3
Theoretical pI 9.35
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
MGALVIRGIRNFNLENRAEREISKMKPSVAPRHPSTNSLLREQISLYPEVKGEIARKDEK
LLSFLKDVYVDSKDPVSSLQVKAAETCQEPKEFRLPKDHHFDMINIKSIPKGKISIVEAL
TLLNNHKLFPETWTAEKIMQEYQLEQKDVNSLLKYFVTFEVEIFPPEDKKAIRSK
GenBank ID Protein 12001966
UniProtKB/Swiss-Prot ID Q9P032
UniProtKB/Swiss-Prot Entry Name NDUF4_HUMAN
PDB IDs Not Available
GenBank Gene ID AF060508
GeneCard ID NDUFAF4
GenAtlas ID NDUFAF4
HGNC ID HGNC:21034
References
General References Not Available