Identification |
HMDB Protein ID
| CDBP04097 |
Secondary Accession Numbers
| Not Available |
Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4 |
Description
| Not Available |
Synonyms
|
- Hormone-regulated proliferation-associated protein of 20 kDa
|
Gene Name
| NDUFAF4 |
Protein Type
| Enzyme |
Biological Properties |
General Function
| Involved in calmodulin binding |
Specific Function
| Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I). May be involved in cell proliferation and survival of hormone-dependent tumor cells. May be a regulator of breast tumor cell invasion |
GO Classification
|
Not Available
|
Cellular Location
|
- Mitochondrion
|
Pathways
|
Not Available
|
Gene Properties |
Chromosome Location
| Chromosome:6 |
Locus
| 6q16.1 |
SNPs
| NDUFAF4 |
Gene Sequence
|
>528 bp
ATGGGAGCACTAGTGATTCGCGGTATCAGGAATTTCAACCTAGAGAACCGAGCGGAACGG
GAAATCAGCAAGATGAAGCCCTCTGTCGCTCCCAGACACCCCTCTACCAACAGCCTCCTG
CGAGAGCAGATTAGTCTCTATCCAGAAGTTAAAGGAGAGATTGCTCGTAAAGATGAAAAG
CTGCTGTCGTTTCTAAAAGATGTGTATGTTGATTCCAAAGATCCTGTGTCTTCCTTGCAG
GTAAAAGCTGCTGAAACATGTCAAGAGCCGAAGGAATTCAGATTGCCGAAAGACCATCAT
TTTGATATGATAAATATTAAGAGCATTCCCAAAGGCAAAATTTCCATTGTAGAAGCATTG
ACACTTCTCAATAATCATAAGCTTTTCCCAGAAACCTGGACTGCTGAGAAAATAATGCAA
GAATACCAGTTAGAACAGAAAGATGTGAATTCTCTTCTTAAATATTTTGTTACTTTTGAA
GTCGAAATCTTCCCTCCTGAAGACAAGAAAGCAATACGATCAAAATGA
|
Protein Properties |
Number of Residues
| 175 |
Molecular Weight
| 20266.3 |
Theoretical pI
| 9.35 |
Pfam Domain Function
|
|
Signals
|
|
Transmembrane Regions
|
|
Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4
MGALVIRGIRNFNLENRAEREISKMKPSVAPRHPSTNSLLREQISLYPEVKGEIARKDEK
LLSFLKDVYVDSKDPVSSLQVKAAETCQEPKEFRLPKDHHFDMINIKSIPKGKISIVEAL
TLLNNHKLFPETWTAEKIMQEYQLEQKDVNSLLKYFVTFEVEIFPPEDKKAIRSK
|
External Links |
GenBank ID Protein
| 12001966 |
UniProtKB/Swiss-Prot ID
| Q9P032 |
UniProtKB/Swiss-Prot Entry Name
| NDUF4_HUMAN |
PDB IDs
|
Not Available |
GenBank Gene ID
| AF060508 |
GeneCard ID
| NDUFAF4 |
GenAtlas ID
| NDUFAF4 |
HGNC ID
| HGNC:21034 |
References |
General References
| Not Available |